PITA_71 megaCluster: 2 Residual: 0.15 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_71	2	0.15	15	0	0.956303	0

Members

Displaying 1 - 28 of 28

100040462 myeloid nuclear differentiation antigen like Details for - - myeloid nuclear differentiation antigen like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100040462 Tuberculist Genomic Region	108673 coiled-coil domain containing 86 Details for MNCb-4327 - coiled-coil domain containing 86 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108673 Tuberculist Genomic Region
12389 caveolin 1, caveolae protein Details for - - caveolin 1, caveolae protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12389 Tuberculist Genomic Region	12494 CD38 antigen Details for - - CD38 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12494 Tuberculist Genomic Region
15958 interferon-induced protein with tetratricopeptide repeats 2 Details for - - interferon-induced protein with tetratricopeptide repeats 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15958 Tuberculist Genomic Region	16816 lecithin cholesterol acyltransferase Details for - - lecithin cholesterol acyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16816 Tuberculist Genomic Region
170768 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Details for RP23-428M4.3 - 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170768 Tuberculist Genomic Region	19024 PTPRF interacting protein, binding protein 2 (liprin beta 2) Details for - - PTPRF interacting protein, binding protein 2 (liprin beta 2) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19024 Tuberculist Genomic Region
19106 eukaryotic translation initiation factor 2-alpha kinase 2 Details for - - eukaryotic translation initiation factor 2-alpha kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19106 Tuberculist Genomic Region	19124 protein C receptor, endothelial Details for RP23-388H13.2 - protein C receptor, endothelial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19124 Tuberculist Genomic Region
19252 dual specificity phosphatase 1 Details for - - dual specificity phosphatase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19252 Tuberculist Genomic Region	22146 tubulin, alpha 1C Details for - - tubulin, alpha 1C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22146 Tuberculist Genomic Region
22169 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial Details for - - cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22169 Tuberculist Genomic Region	240327 predicted gene 4951 Details for - - predicted gene 4951 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240327 Tuberculist Genomic Region
269181 mannoside acetylglucosaminyltransferase 4, isoenzyme A Details for - - mannoside acetylglucosaminyltransferase 4, isoenzyme A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 269181 Tuberculist Genomic Region	319765 insulin-like growth factor 2 mRNA binding protein 2 Details for RP23-50H13.1 - insulin-like growth factor 2 mRNA binding protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 319765 Tuberculist Genomic Region
59027 nicotinamide phosphoribosyltransferase Details for - - nicotinamide phosphoribosyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 59027 Tuberculist Genomic Region	60440 interferon inducible GTPase 1 Details for - - interferon inducible GTPase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60440 Tuberculist Genomic Region
631323 predicted gene 12250 Details for - - predicted gene 12250 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 631323 Tuberculist Genomic Region	71586 interferon induced with helicase C domain 1 Details for RP23-34J8.2 - interferon induced with helicase C domain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71586 Tuberculist Genomic Region
76199 mediator complex subunit 13-like Details for - - mediator complex subunit 13-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76199 Tuberculist Genomic Region	209200 deltex 3-like (Drosophila) Details for - - deltex 3-like (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 209200 Tuberculist Genomic Region
22040 three prime repair exonuclease 1 Details for - - three prime repair exonuclease 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22040 Tuberculist Genomic Region	327978 schlafen 5 Details for RP23-392I13.5 - schlafen 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 327978 Tuberculist Genomic Region
667370 RIKEN cDNA I830012O16 gene Details for - - RIKEN cDNA I830012O16 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 667370 Tuberculist Genomic Region	20779 Rous sarcoma oncogene Details for RP23-169M4.1 - Rous sarcoma oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20779 Tuberculist Genomic Region
241447 ceramide synthase 6 Details for RP23-431D4.1 - ceramide synthase 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241447 Tuberculist Genomic Region	80750 NEDD4 binding protein 1 Details for - - NEDD4 binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 80750 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
Isgf3g.1	0.321429	0.0000000101

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000002	ANGAAASWGAAA	STAT1_MA0137.1, IRF1_MA0050.1, IRF2_MA0051.1, V$IRF1_Q6_M00747, V$IRF2_Q6_M01882, V$IRF_Q6_01_M00972, V$IRF1_Q6_01_M01881, V$IRF7_Q3_M01884, V$ISRE_01_M00258, V$IRF7_01_M00453, V$IRF_Q6_M00772, IRF7_IRF_DBD_dimeric_14_1, IRF9_IRF_full_trimeric_15_1, PRDM1_C2H2_full_monomeric-or-dimeric_15_1, IRF3_IRF_full_trimeric_21_1, IRF8_IRF_full_dimeric_14_1, IRF4_IRF_full_dimeric_15_1	0.0083	AGARNNAGRAA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
0.9	CGAGCC	NA	0.96	CTGGCTCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.49	NGACTT	NA	NA	0.58	TCAAGTAC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-539	0.944444	0.00000341

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-383	0.478261	0.000000596

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