PITA_86 megaCluster: 11 Residual: 0.17

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_86	11	0.17	15	0	0.945903	0

Members

Displaying 1 - 43 of 43

TFBS DB TF

TFs	percTargets	pValue
E2F3_E2F_DBD_dimeric_18_2	0.116279	0.0000122

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000023	ANAAARAAAAA	NA	0.056	GCCCCGCCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$SP1_03_M02281, V$SP1_Q2_01_M00933, V$UF1H3BETA_Q6_M01068, V$GC_01_M00255, V$SP4_03_M02810, V$ZFP281_01_M01597, V$GKLF_02_M01588, V$KLF7_03_M02773, V$EGR1_Q6_M01873, V$SP2_01_M01783, V$KROX_Q6_M00982, V$EGR1_06_M02744, V$ZNF219_01_M01122, V$SP1_02_M01303, V$E2F3_Q6_M02089, V$MAZR_01_M00491, V$CKROX_Q2_M01175, V$MAZ_Q6_M00649, V$ZBP89_Q4_M01816, V$ZFP281_04_M02831, V$CACD_01_M01113, V$SMAD4_04_M02898, V$WT1_Q6_01_M02036, V$SP1_01_M00008, V$MAZ_Q6_01_M02023, V$CACBINDINGPROTEIN_Q6_M00720, V$E2F_Q2_M00803, V$EKLF_Q5_M01874, V$EGR_Q6_M00807, V$SP1SP3_Q4_M01219, Sp4.1, Klf7.1, Egr1.1, Zfp281.2, Smad3.1, Bcl6b.2, Zfp410.1, Zif268.1, Zfp740.1, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, Klf12_C2H2_DBD_monomeric_15_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.43	CGCGAA	V$E2F1_Q6_01_M00940, V$E2F_Q6_M00427, V$E2F1_Q6_M00431, V$E2F_01_M00024, V$E2F_Q4_M00426, V$E2F_Q3_01_M00918, V$E2F_Q4_02_M00939, V$E2F_Q3_M00425, V$E2F4DP1_01_M00738, V$E2F_03_M00516, V$E2F_Q4_01_M00919, V$E2F_Q6_01_M00920, V$E2F_02_M00050, V$E2F1DP1RB_01_M00740	1.42	CGAACCGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.44	CGTCGG	NA	NA	0.64	GTCNGTCC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

13476 receptor accessory protein 5 Details for - - receptor accessory protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13476 Tuberculist Genomic Region	13864 nuclear receptor subfamily 2, group F, member 6 Details for - - nuclear receptor subfamily 2, group F, member 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13864 Tuberculist Genomic Region
14590 gamma-glutamyl hydrolase Details for RP23-259B18.3 - gamma-glutamyl hydrolase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14590 Tuberculist Genomic Region	21856 translocase of inner mitochondrial membrane 44 Details for - - translocase of inner mitochondrial membrane 44 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21856 Tuberculist Genomic Region
226594 RCSD domain containing 1 Details for - - RCSD domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226594 Tuberculist Genomic Region	228033 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) Details for RP23-146O7.1 - ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228033 Tuberculist Genomic Region
59001 polymerase (DNA directed), epsilon 3 (p17 subunit) Details for RP24-189G18.8 - polymerase (DNA directed), epsilon 3 (p17 subunit) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 59001 Tuberculist Genomic Region	67872 non-SMC element 4 homolog A (S. cerevisiae) Details for - - non-SMC element 4 homolog A (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67872 Tuberculist Genomic Region
68047 MPN domain containing Details for RP23-65P17.2 - MPN domain containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68047 Tuberculist Genomic Region	68598 DnaJ (Hsp40) homolog, subfamily C, member 8 Details for RP23-63D8.7 - DnaJ (Hsp40) homolog, subfamily C, member 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68598 Tuberculist Genomic Region
69029 single-pass membrane protein with aspartate rich tail 1 Details for - - single-pass membrane protein with aspartate rich tail 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69029 Tuberculist Genomic Region	70454 centromere protein L Details for - - centromere protein L GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70454 Tuberculist Genomic Region
71735 leucine-rich repeats and WD repeat domain containing 1 Details for - - leucine-rich repeats and WD repeat domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71735 Tuberculist Genomic Region	77252 RIKEN cDNA 9430038I01 gene Details for - - RIKEN cDNA 9430038I01 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77252 Tuberculist Genomic Region
77605 H2A histone family, member V Details for RP23-74L9.1 - H2A histone family, member V GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77605 Tuberculist Genomic Region	12850 demethyl-Q 7 Details for - - demethyl-Q 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12850 Tuberculist Genomic Region
225995 RIKEN cDNA D030056L22 gene Details for - - RIKEN cDNA D030056L22 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225995 Tuberculist Genomic Region	233876 HIRA interacting protein 3 Details for - - HIRA interacting protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233876 Tuberculist Genomic Region
28080 ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit Details for - - ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 28080 Tuberculist Genomic Region	56350 ADP-ribosylation factor-like 3 Details for - - ADP-ribosylation factor-like 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56350 Tuberculist Genomic Region
67196 ubiquitin-conjugating enzyme E2T (putative) Details for - - ubiquitin-conjugating enzyme E2T (putative) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67196 Tuberculist Genomic Region	73419 RIKEN cDNA 1700052N19 gene Details for - - RIKEN cDNA 1700052N19 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73419 Tuberculist Genomic Region
12531 cell division cycle 25B Details for RP23-387C21.1 - cell division cycle 25B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12531 Tuberculist Genomic Region	13666 eukaryotic translation initiation factor 2 alpha kinase 3 Details for - - eukaryotic translation initiation factor 2 alpha kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13666 Tuberculist Genomic Region
140500 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 Details for RP23-242K15.11-002 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 140500 Tuberculist Genomic Region	26886 centromere protein H Details for - - centromere protein H GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26886 Tuberculist Genomic Region
381318 NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) Details for - - NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381318 Tuberculist Genomic Region	65098 zinc finger, AN1-type domain 6 Details for - - zinc finger, AN1-type domain 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65098 Tuberculist Genomic Region
66578 MIS18 kinetochore protein homolog A (S. pombe) Details for - - MIS18 kinetochore protein homolog A (S. pombe) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66578 Tuberculist Genomic Region	68183 breast carcinoma amplified sequence 2 Details for - - breast carcinoma amplified sequence 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68183 Tuberculist Genomic Region
110006 glucuronidase, beta Details for - - glucuronidase, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110006 Tuberculist Genomic Region	12412 chromobox 1 Details for RP23-353J21.1 - chromobox 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12412 Tuberculist Genomic Region
14375 X-ray repair complementing defective repair in Chinese hamster cells 6 Details for - - X-ray repair complementing defective repair in Chinese hamster cells 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14375 Tuberculist Genomic Region	19355 RAD1 homolog (S. pombe) Details for - - RAD1 homolog (S. pombe) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19355 Tuberculist Genomic Region
224111 UBX domain protein 7 Details for - - UBX domain protein 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 224111 Tuberculist Genomic Region	225745 HAUS augmin-like complex, subunit 1 Details for - - HAUS augmin-like complex, subunit 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225745 Tuberculist Genomic Region
381306 cDNA sequence BC055324 Details for - - cDNA sequence BC055324 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381306 Tuberculist Genomic Region	67141 F-box protein 5 Details for - - F-box protein 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67141 Tuberculist Genomic Region
83409 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Details for - - late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 83409 Tuberculist Genomic Region	109778 biliverdin reductase A Details for RP23-26A12.2 - biliverdin reductase A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109778 Tuberculist Genomic Region
26385 G protein-coupled receptor kinase 6 Details for - - G protein-coupled receptor kinase 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26385 Tuberculist Genomic Region	66455 canopy 4 homolog (zebrafish) Details for - - canopy 4 homolog (zebrafish) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66455 Tuberculist Genomic Region
20833 structure specific recognition protein 1 Details for RP23-232L15.5 - structure specific recognition protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20833 Tuberculist Genomic Region

Summary

Members

Details for - - receptor accessory protein 5

Details for - - nuclear receptor subfamily 2, group F, member 6

Details for RP23-259B18.3 - gamma-glutamyl hydrolase

Details for - - translocase of inner mitochondrial membrane 44

Details for - - RCSD domain containing 1

Details for RP23-146O7.1 - ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

Details for RP24-189G18.8 - polymerase (DNA directed), epsilon 3 (p17 subunit)

Details for - - non-SMC element 4 homolog A (S. cerevisiae)

Details for RP23-65P17.2 - MPN domain containing

Details for RP23-63D8.7 - DnaJ (Hsp40) homolog, subfamily C, member 8

Details for - - single-pass membrane protein with aspartate rich tail 1

Details for - - centromere protein L

Details for - - leucine-rich repeats and WD repeat domain containing 1

Details for - - RIKEN cDNA 9430038I01 gene

Details for RP23-74L9.1 - H2A histone family, member V

Details for - - demethyl-Q 7

Details for - - RIKEN cDNA D030056L22 gene

Details for - - HIRA interacting protein 3

Details for - - ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit

Details for - - ADP-ribosylation factor-like 3

Details for - - ubiquitin-conjugating enzyme E2T (putative)

Details for - - RIKEN cDNA 1700052N19 gene

Details for RP23-387C21.1 - cell division cycle 25B

Details for - - eukaryotic translation initiation factor 2 alpha kinase 3

Details for RP23-242K15.11-002 - ArfGAP with coiled-coil, ankyrin repeat and PH domains 3

Details for - - centromere protein H

Details for - - NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

Details for - - zinc finger, AN1-type domain 6

Details for - - MIS18 kinetochore protein homolog A (S. pombe)

Details for - - breast carcinoma amplified sequence 2

Details for - - glucuronidase, beta

Details for RP23-353J21.1 - chromobox 1

Details for - - X-ray repair complementing defective repair in Chinese hamster cells 6

Details for - - RAD1 homolog (S. pombe)

Details for - - UBX domain protein 7

Details for - - HAUS augmin-like complex, subunit 1

Details for - - cDNA sequence BC055324

Details for - - F-box protein 5

Details for - - late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

Details for RP23-26A12.2 - biliverdin reductase A

Details for - - G protein-coupled receptor kinase 6

Details for - - canopy 4 homolog (zebrafish)

Details for RP23-232L15.5 - structure specific recognition protein 1

GO Terms

3p UTR PITA