PITA_87 megaCluster: 7 Residual: 0.18

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
PITA_87 7 0.18 15 0 0.937286 0

Members

Displaying 1 - 36 of 36
19364 RAD51 homolog D

Details for RP23-169P3.1 - RAD51 homolog D

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19364

Tuberculist Genomic Region

216445 Rho GTPase activating protein 9

Details for - - Rho GTPase activating protein 9

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 216445

Tuberculist Genomic Region

226151 family with sequence similarity 178, member A

Details for - - family with sequence similarity 178, member A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 226151

Tuberculist Genomic Region

229603 OTU domain containing 7B

Details for - - OTU domain containing 7B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 229603

Tuberculist Genomic Region

236794 solute carrier family 9 (sodium/hydrogen exchanger), member 6

Details for RP23-105E2.4 - solute carrier family 9 (sodium/hydrogen exchanger), member 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 236794

Tuberculist Genomic Region

245638 TBC1 domain family, member 8B

Details for - - TBC1 domain family, member 8B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 245638

Tuberculist Genomic Region

245866 intraflagellar transport 52

Details for RP23-335N12.4 - intraflagellar transport 52

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 245866

Tuberculist Genomic Region

327762 DNA replication helicase 2 homolog (yeast)

Details for - - DNA replication helicase 2 homolog (yeast)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 327762

Tuberculist Genomic Region

53951 G patch domain containing 11

Details for - - G patch domain containing 11

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 53951

Tuberculist Genomic Region

545938 zinc finger proten 607

Details for - - zinc finger proten 607

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 545938

Tuberculist Genomic Region

67422 dehydrodolichyl diphosphate synthase

Details for RP23-256C7.6 - dehydrodolichyl diphosphate synthase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67422

Tuberculist Genomic Region

69962 methyltransferase like 18

Details for - - methyltransferase like 18

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69962

Tuberculist Genomic Region

72144 solute carrier family 37 (glycerol-3-phosphate transporter), member 3

Details for - - solute carrier family 37 (glycerol-3-phosphate transporter), member 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 72144

Tuberculist Genomic Region

98193 DDB1 and CUL4 associated factor 8

Details for - - DDB1 and CUL4 associated factor 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 98193

Tuberculist Genomic Region

100972 RAB28, member RAS oncogene family

Details for - - RAB28, member RAS oncogene family

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100972

Tuberculist Genomic Region

17347 MAP kinase-interacting serine/threonine kinase 2

Details for - - MAP kinase-interacting serine/threonine kinase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 17347

Tuberculist Genomic Region

192169 UFM1-specific peptidase 2

Details for - - UFM1-specific peptidase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 192169

Tuberculist Genomic Region

217695 zinc finger, FYVE domain containing 1

Details for - - zinc finger, FYVE domain containing 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 217695

Tuberculist Genomic Region

22225 ubiquitin specific peptidase 5 (isopeptidase T)

Details for - - ubiquitin specific peptidase 5 (isopeptidase T)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22225

Tuberculist Genomic Region

228913 zinc finger protein 217

Details for RP23-233M15.1 - zinc finger protein 217

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 228913

Tuberculist Genomic Region

237082 nuclear transport factor 2-like export factor 2

Details for RP23-161L11.3 - nuclear transport factor 2-like export factor 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 237082

Tuberculist Genomic Region

54607 suppressor of cytokine signaling 6

Details for - - suppressor of cytokine signaling 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 54607

Tuberculist Genomic Region

60365 RNA binding motif protein 8a

Details for - - RNA binding motif protein 8a

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 60365

Tuberculist Genomic Region

66559 methionyl aminopeptidase type 1D (mitochondrial)

Details for RP23-419H3.1 - methionyl aminopeptidase type 1D (mitochondrial)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66559

Tuberculist Genomic Region

66822 F-box protein 25

Details for - - F-box protein 25

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 66822

Tuberculist Genomic Region

67013 OMA1 homolog, zinc metallopeptidase (S. cerevisiae)

Details for RP23-47A6.4 - OMA1 homolog, zinc metallopeptidase (S. cerevisiae)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67013

Tuberculist Genomic Region

69871 protein phosphatase 1, regulatory subunit 35

Details for - - protein phosphatase 1, regulatory subunit 35

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69871

Tuberculist Genomic Region

74159 acyl-Coenzyme A binding domain containing 5

Details for RP23-280K4.2 - acyl-Coenzyme A binding domain containing 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74159

Tuberculist Genomic Region

65099 interleukin-1 receptor-associated kinase 1 binding protein 1

Details for - - interleukin-1 receptor-associated kinase 1 binding protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 65099

Tuberculist Genomic Region

80743 vacuolar protein sorting 16 (yeast)

Details for RP23-29K12.8 - vacuolar protein sorting 16 (yeast)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 80743

Tuberculist Genomic Region

105513 charged multivesicular body protein 7

Details for - - charged multivesicular body protein 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 105513

Tuberculist Genomic Region

230514 leptin receptor overlapping transcript

Details for RP23-31K16.1 - leptin receptor overlapping transcript

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 230514

Tuberculist Genomic Region

56357 isovaleryl coenzyme A dehydrogenase

Details for RP23-172B16.1 - isovaleryl coenzyme A dehydrogenase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56357

Tuberculist Genomic Region

26889 ceroid-lipofuscinosis, neuronal 8

Details for - - ceroid-lipofuscinosis, neuronal 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 26889

Tuberculist Genomic Region

235339 dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)

Details for - - dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 235339

Tuberculist Genomic Region

69596 adaptor-related protein 5 complex, sigma 1 subunit

Details for RP23-387C21.2 - adaptor-related protein 5 complex, sigma 1 subunit

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 69596

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
NA

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.000046 GGGGGCGGGGST SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$SP1_Q2_01_M00933, V$SP1_Q4_01_M00932, V$SP1_03_M02281, V$GC_01_M00255, V$ZFP281_01_M01597, V$SP1_02_M01303, V$ZBP89_Q4_M01816, V$EGR1_Q6_M01873, V$UF1H3BETA_Q6_M01068, V$SP4_03_M02810, V$CKROX_Q2_M01175, V$ZFP281_04_M02831, V$KLF7_03_M02773, V$GKLF_02_M01588, V$EGR1_06_M02744, V$KROX_Q6_M00982, V$MAZR_01_M00491, V$BCL6B_04_M02844, V$SP1SP3_Q4_M01219, V$ETF_Q6_M00695, V$MAZ_Q6_M00649, V$WT1_Q6_01_M02036, V$SP1_01_M00008, V$ZNF219_01_M01122, V$MAZ_Q6_01_M02023, V$CACBINDINGPROTEIN_Q6_M00720, V$SMAD4_04_M02898, V$SP2_01_M01783, V$EGR_Q6_M00807, V$FKLF_Q5_M01837, V$E2F3_Q6_M02089, V$CACD_01_M01113, V$ZFP740_03_M02834, V$NGFIC_01_M00244, V$EGR1_02_M01972, V$WT1_Q6_M01118, V$ZFP410_04_M02936, V$EKLF_Q5_M01874, V$RNF96_01_M01199, V$FPM315_01_M01587, V$GLI3_Q5_01_M01657, V$KLF15_Q2_M01714, V$EGR2_Q6_M02092, V$EGR1_01_M00243, Sp4.1, Zfp281.2, Egr1.1, Klf7.1, Bcl6b.2, Smad3.1, Zfp740.1, Zif268.1, Zfp410.1, Ascl2.2, Sox13.2, Egr1.2, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1, KLF14_C2H2_DBD_monomeric_14_1, Zfp740_C2H2_DBD_monomeric_10_1, KLF13_C2H2_full_monomeric_18_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, EGR2_C2H2_full_monomeric_15_1 0.027 AAAMARAMMAAC NA

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.1 TGGCGG V$SMAD4_04_M02898, Smad3.1, E2F8_E2F_DBD_dimeric_12_1, YY2_C2H2_full_dimeric_12_1, YY2_C2H2_full_monomeric_11_1 1.28 CGRCGCGT NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.5 TACTGNNC NA NA NA NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-3071 0.46875 0.0000263

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