TargetScan_124 megaCluster: 3 Residual: 0.22 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_124	3	0.22	15	0	0.908563	0

Members

Displaying 1 - 22 of 22

12393 runt related transcription factor 2 Details for - - runt related transcription factor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12393 Tuberculist Genomic Region	14284 fos-like antigen 2 Details for - - fos-like antigen 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14284 Tuberculist Genomic Region
20218 KH domain containing, RNA binding, signal transduction associated 1 Details for RP23-151A15.11-002 - KH domain containing, RNA binding, signal transduction associated 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20218 Tuberculist Genomic Region	27215 5-azacytidine induced gene 2 Details for - - 5-azacytidine induced gene 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27215 Tuberculist Genomic Region
53376 ubiquitin specific peptidase 2 Details for MNCb-0190 - ubiquitin specific peptidase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53376 Tuberculist Genomic Region	54216 protocadherin 7 Details for - - protocadherin 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54216 Tuberculist Genomic Region
54616 exostoses (multiple)-like 3 Details for - - exostoses (multiple)-like 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54616 Tuberculist Genomic Region	75379 RIKEN cDNA 4930599N23 gene Details for - - RIKEN cDNA 4930599N23 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75379 Tuberculist Genomic Region
100198 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) Details for RP23-169H13.3 - hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100198 Tuberculist Genomic Region	13051 fatty acid binding protein 7, brain Details for - - fatty acid binding protein 7, brain GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12140 Tuberculist Genomic Region
16408 chemokine (C-X3-C motif) receptor 1 Details for - - chemokine (C-X3-C motif) receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13051 Tuberculist Genomic Region	170676 integrin alpha L Details for - - integrin alpha L GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16408 Tuberculist Genomic Region
20393 paternally expressed 10 Details for - - paternally expressed 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170676 Tuberculist Genomic Region	22146 serum/glucocorticoid regulated kinase 1 Details for - - serum/glucocorticoid regulated kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20393 Tuberculist Genomic Region
667597 tubulin, alpha 1C Details for - - tubulin, alpha 1C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22146 Tuberculist Genomic Region	67399 cDNA sequence BC023105 Details for - - cDNA sequence BC023105 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 667597 Tuberculist Genomic Region
67916 PDZ and LIM domain 7 Details for RP23-211O9.2 - PDZ and LIM domain 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67399 Tuberculist Genomic Region	71254 phosphatidic acid phosphatase type 2B Details for RP23-104G20.1 - phosphatidic acid phosphatase type 2B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67916 Tuberculist Genomic Region
76800 nuclear apoptosis inducing factor 1 Details for RP23-255P20.2 - nuclear apoptosis inducing factor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71254 Tuberculist Genomic Region	13518 ubiquitin specific peptidase 42 Details for - - ubiquitin specific peptidase 42 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76800 Tuberculist Genomic Region
20779 dystonin Details for - - dystonin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13518 Tuberculist Genomic Region	Details for RP23-169M4.1 - Rous sarcoma oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20779 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
Zfp281.2, SP1_MA0079.2, V_SP1_03_M02281, V_UF1H3BETA_Q6_M01068, V_MAZ_Q6_01_M02023, Ascl2.2, V_CKROX_Q2_M01175, V_SP4_Q5_M01273, V_CACBINDINGPROTEIN_Q6_M00720, V_ASCL2_04_M02841, V_ZFP281_01_M01597, V_ZFP281_04_M02831, V_SP1_Q2_01_M00933	1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000032	MTTTYTTTTTYT	NA	1.6	GGGSGKGGRGGR	Klf4_MA0039.2, V$MAZ_Q6_01_M02023, V$ZFP281_04_M02831, V$CACD_01_M01113, V$KLF7_03_M02773, V$ZBP89_Q4_M01816, V$EKLF_Q5_M01874, V$SP1_02_M01303, V$ZFP281_01_M01597, V$GKLF_02_M01588, V$ZFP740_03_M02834, V$SP1SP3_Q4_M01219, V$MAZR_01_M00491, V$SP4_Q5_M01273, V$KROX_Q6_M00982, V$CKROX_Q2_M01175, V$UF1H3BETA_Q6_M01068, V$SP1_03_M02281, V$SP1_Q2_01_M00933, V$MAZ_Q6_M00649, V$ZNF219_01_M01122, V$SP1_Q6_01_M00931, V$FKLF_Q5_M01837, V$EGR1_Q6_M01873, V$FPM315_01_M01587, V$EGR2_Q6_M02092, V$WT1_Q6_01_M02036, V$CACCCBINDINGFACTOR_Q6_M00721, V$SP1_Q4_01_M00932, V$ETF_Q6_M00695, V$EGR_Q6_M00807, V$SP1_Q6_M00196, V$EGR1_06_M02744, V$KID3_01_M01160, Zfp281.2, Klf7.1, Zfp740.1, Egr1.1, Sp4.1, Ascl2.2, Smad3.1, Bcl6b.2, Zfp410.1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP4_C2H2_full_monomeric_17_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.14	CGCGGA	NA	1.45	GCGAGAGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.69	CCCCGT	NA	NA	0.93	GTCTCNAC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-673-3p	0.647059	0.0000524

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-3096b-5p	0.611111	0.00000183

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