Runx2 runt related transcription factor 2 (12393)

Symbol Product Feature Type Strand Chr
12393 Runx2 runt related transcription factor 2 protein-coding 17
Synonyms
AML3 | Cbf | Cbfa-1 | Cbfa1 | LS3 | Osf2 | PEBP2aA | Pebp2a1 | Pebpa2a
GO ID Category Definition Evidence
  • nuclear chromatin
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding
  • RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
  • skeletal system development
  • osteoblast differentiation
  • endochondral ossification
  • osteoblast fate commitment
  • chondrocyte differentiation
  • chondrocyte development
  • osteoblast development
  • DNA binding
  • chromatin binding
  • sequence-specific DNA binding transcription factor activity
  • protein binding
  • ATP binding
  • nucleus
  • transcription factor complex
  • cytoplasm
  • transcription, DNA-templated
  • regulation of transcription, DNA-templated
  • transcription factor binding
  • positive regulation of cell proliferation
  • protein domain specific binding
  • T cell differentiation
  • regulation of ossification
  • BMP signaling pathway
  • positive regulation of chondrocyte differentiation
  • embryonic forelimb morphogenesis
  • regulation of fibroblast growth factor receptor signaling pathway
  • odontogenesis of dentin-containing tooth
  • regulation of odontogenesis of dentin-containing tooth
  • bHLH transcription factor binding
  • transcription regulatory region DNA binding
  • regulation of osteoblast differentiation
  • positive regulation of osteoblast differentiation
  • positive regulation of ossification
  • negative regulation of smoothened signaling pathway
  • negative regulation of transcription, DNA-templated
  • positive regulation of transcription, DNA-templated
  • positive regulation of transcription from RNA polymerase II promoter
  • cell maturation
  • embryonic cranial skeleton morphogenesis
  • skeletal system morphogenesis
  • stem cell differentiation
  • repressing transcription factor binding
  • cellular response to BMP stimulus
  • positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus
Motif 1 Motif 2 Residual
PITA_116 |
Residual: 
0.28
0.28
PITA_56 |
Residual: 
0.20
0.20
TargetScan_124 |
Residual: 
0.22
0.22
TargetScan_161 |
Residual: 
0.20
0.20
TargetScan_228 |
Residual: 
0.25
0.25
TargetScan_57 |
Residual: 
0.21
0.21
Displaying 1 - 6 of 6
Entrez ID STRINGS Network
STRING
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