TargetScan_130 megaCluster: 11 Residual: 0.17 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_130	11	0.17	15	0	0.949701	0

Members

Displaying 1 - 35 of 35

13194 damage specific DNA binding protein 1 Details for - - damage specific DNA binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13194 Tuberculist Genomic Region	13205 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked Details for RP23-158L19.4 - DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13205 Tuberculist Genomic Region
14661 glutamate dehydrogenase 1 Details for - - glutamate dehydrogenase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14661 Tuberculist Genomic Region	15473 heat-responsive protein 12 Details for - - heat-responsive protein 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15473 Tuberculist Genomic Region
16211 karyopherin (importin) beta 1 Details for RP23-81D2.3 - karyopherin (importin) beta 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16211 Tuberculist Genomic Region	22643 zinc finger protein 101 Details for - - zinc finger protein 101 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22643 Tuberculist Genomic Region
231123 HAUS augmin-like complex, subunit 3 Details for - - HAUS augmin-like complex, subunit 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231123 Tuberculist Genomic Region	52715 coiled-coil domain containing 43 Details for RP23-57F11.7 - coiled-coil domain containing 43 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52715 Tuberculist Genomic Region
75296 Fgfr1 oncogene partner Details for - - Fgfr1 oncogene partner GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75296 Tuberculist Genomic Region	78894 acetoacetyl-CoA synthetase Details for - - acetoacetyl-CoA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78894 Tuberculist Genomic Region
83409 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Details for - - late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 83409 Tuberculist Genomic Region	100233175 cDNA sequence AK010878 Details for - - cDNA sequence AK010878 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100233175 Tuberculist Genomic Region
13018 CCCTC-binding factor Details for - - CCCTC-binding factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13018 Tuberculist Genomic Region	18020 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein Details for - - nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18020 Tuberculist Genomic Region
225995 RIKEN cDNA D030056L22 gene Details for - - RIKEN cDNA D030056L22 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225995 Tuberculist Genomic Region	237823 phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) Details for RP23-153N12.1 - phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 237823 Tuberculist Genomic Region
30045 DnaJ (Hsp40) homolog, subfamily C, member 12 Details for - - DnaJ (Hsp40) homolog, subfamily C, member 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30045 Tuberculist Genomic Region	381101 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 Details for - - 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381101 Tuberculist Genomic Region
53861 zinc finger, RAN-binding domain containing 2 Details for - - zinc finger, RAN-binding domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53861 Tuberculist Genomic Region	53951 G patch domain containing 11 Details for - - G patch domain containing 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53951 Tuberculist Genomic Region
56040 ribosomal protein, large, P1 Details for - - ribosomal protein, large, P1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56040 Tuberculist Genomic Region	67139 MIS12 homolog (yeast) Details for DN-393H17.5 - MIS12 homolog (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67139 Tuberculist Genomic Region
67203 nuclear distribution gene E homolog 1 (A nidulans) Details for - - nuclear distribution gene E homolog 1 (A nidulans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67203 Tuberculist Genomic Region	67959 poly-U binding splicing factor 60 Details for - - poly-U binding splicing factor 60 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67959 Tuberculist Genomic Region
78372 small nuclear ribonucleoprotein 25 (U11/U12) Details for RP23-177M10.3 - small nuclear ribonucleoprotein 25 (U11/U12) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78372 Tuberculist Genomic Region	12757 clathrin, light polypeptide (Lca) Details for RP23-209M8.4 - clathrin, light polypeptide (Lca) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12757 Tuberculist Genomic Region
13666 eukaryotic translation initiation factor 2 alpha kinase 3 Details for - - eukaryotic translation initiation factor 2 alpha kinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13666 Tuberculist Genomic Region	53975 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 Details for - - DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53975 Tuberculist Genomic Region
66868 major facilitator superfamily domain containing 1 Details for - - major facilitator superfamily domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66868 Tuberculist Genomic Region	109900 argininosuccinate lyase Details for - - argininosuccinate lyase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109900 Tuberculist Genomic Region
14375 X-ray repair complementing defective repair in Chinese hamster cells 6 Details for - - X-ray repair complementing defective repair in Chinese hamster cells 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14375 Tuberculist Genomic Region	20833 structure specific recognition protein 1 Details for RP23-232L15.5 - structure specific recognition protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20833 Tuberculist Genomic Region
217558 G2/M-phase specific E3 ubiquitin ligase Details for - - G2/M-phase specific E3 ubiquitin ligase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217558 Tuberculist Genomic Region	76687 signal peptidase complex subunit 3 homolog (S. cerevisiae) Details for - - signal peptidase complex subunit 3 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76687 Tuberculist Genomic Region
99167 synovial sarcoma, X breakpoint 2 interacting protein Details for - - synovial sarcoma, X breakpoint 2 interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99167 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_MUSCLE_INI_B_M00321	0.971429	0.0000132

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.079	NGCCCCGCCCC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_Q6_01_M00931, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP1_Q2_01_M00933, V$UF1H3BETA_Q6_M01068, V$SP1_03_M02281, V$ZFP281_01_M01597, V$SP1_02_M01303, V$SP2_01_M01783, V$KLF7_03_M02773, V$MAZR_01_M00491, V$CKROX_Q2_M01175, V$ETF_Q6_M00695, V$GKLF_02_M01588, V$MAZ_Q6_M00649, V$SP1_01_M00008, V$ZFP281_04_M02831, V$BCL6B_04_M02844, V$SP4_03_M02810, V$E2F3_Q6_M02089, V$CACD_01_M01113, V$ZFP410_04_M02936, V$SMAD4_04_M02898, V$SP1SP3_Q4_M01219, V$ZBP89_Q4_M01816, V$EGR1_Q6_M01873, V$MAZ_Q6_01_M02023, V$KLF15_Q2_M01714, V$KROX_Q6_M00982, V$ZNF219_01_M01122, V$SP4_04_M02914, V$EGR1_06_M02744, Klf7.1, Zfp281.2, Bcl6b.2, Sp4.1, Zfp410.1, Smad3.1, Egr1.1, Sp4.2, Zfp740.1, Ascl2.2, SP1_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP8_C2H2_DBD_monomeric_12_1, KLF13_C2H2_full_monomeric_18_1, ZNF740_C2H2_full_monomeric_10_1	180	TTTTGAAWKKTG	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.6	CGCGAA	V$E2F1_Q6_01_M00940, V$E2F_Q6_M00427, V$E2F1_Q6_M00431, V$E2F_01_M00024, V$E2F_Q3_M00425, V$E2F_03_M00516, V$E2F_Q4_M00426, V$E2F_Q3_01_M00918, V$E2F4DP1_01_M00738, V$E2F_Q4_02_M00939, V$E2F_Q6_01_M00920, V$E2F1DP1RB_01_M00740, V$E2F_02_M00050, V$E2F_Q4_01_M00919	1.63	GCGGNNCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.41	GTCGCG	NA	NA	0.52	GCNTTGCA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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