TargetScan_142 megaCluster: 8 Residual: 0.19 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_142	8	0.19	15	0	0.936838	0

Members

Displaying 1 - 35 of 35

100036521 predicted gene 16039 Details for - - predicted gene 16039 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100036521 Tuberculist Genomic Region	17193 methyl-CpG binding domain protein 4 Details for - - methyl-CpG binding domain protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17193 Tuberculist Genomic Region
18642 phosphofructokinase, muscle Details for - - phosphofructokinase, muscle GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18642 Tuberculist Genomic Region	20492 stem-loop binding protein Details for - - stem-loop binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20492 Tuberculist Genomic Region
210035 transmembrane protein 194 Details for - - transmembrane protein 194 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 210035 Tuberculist Genomic Region	216724 RUN and FYVE domain containing 1 Details for RP23-121P11.2 - RUN and FYVE domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216724 Tuberculist Genomic Region
223776 selenoprotein O Details for - - selenoprotein O GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223776 Tuberculist Genomic Region	231803 methylphosphate capping enzyme Details for - - methylphosphate capping enzyme GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231803 Tuberculist Genomic Region
66578 MIS18 kinetochore protein homolog A (S. pombe) Details for - - MIS18 kinetochore protein homolog A (S. pombe) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66578 Tuberculist Genomic Region	75735 pantothenate kinase 1 Details for - - pantothenate kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75735 Tuberculist Genomic Region
100532 RELT-like 1 Details for - - RELT-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100532 Tuberculist Genomic Region	101739 PC4 and SFRS1 interacting protein 1 Details for RP23-311B24.4 - PC4 and SFRS1 interacting protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 101739 Tuberculist Genomic Region
12892 coproporphyrinogen oxidase Details for - - coproporphyrinogen oxidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12892 Tuberculist Genomic Region	21749 telomeric repeat binding factor 1 Details for - - telomeric repeat binding factor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21749 Tuberculist Genomic Region
22594 X-ray repair complementing defective repair in Chinese hamster cells 1 Details for - - X-ray repair complementing defective repair in Chinese hamster cells 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22594 Tuberculist Genomic Region	234736 ring finger and WD repeat domain 3 Details for - - ring finger and WD repeat domain 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234736 Tuberculist Genomic Region
319190 histone cluster 2, H2be Details for - - histone cluster 2, H2be GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 319190 Tuberculist Genomic Region	66953 cell division cycle associated 7 Details for RP23-146F24.2 - cell division cycle associated 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66953 Tuberculist Genomic Region
67397 endoplasmic reticulum protein 29 Details for - - endoplasmic reticulum protein 29 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67397 Tuberculist Genomic Region	67872 non-SMC element 4 homolog A (S. cerevisiae) Details for - - non-SMC element 4 homolog A (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67872 Tuberculist Genomic Region
68201 coiled-coil domain containing 34 Details for RP23-300M9.1 - coiled-coil domain containing 34 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68201 Tuberculist Genomic Region	69270 GINS complex subunit 1 (Psf1 homolog) Details for RP23-193L22.1 - GINS complex subunit 1 (Psf1 homolog) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69270 Tuberculist Genomic Region
70238 ring finger protein 168 Details for - - ring finger protein 168 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70238 Tuberculist Genomic Region	70804 progesterone receptor membrane component 2 Details for - - progesterone receptor membrane component 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70804 Tuberculist Genomic Region
71876 centromere protein U Details for - - centromere protein U GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71876 Tuberculist Genomic Region	78412 RIKEN cDNA 3110062M04 gene Details for - - RIKEN cDNA 3110062M04 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78412 Tuberculist Genomic Region
16319 inner centromere protein Details for - - inner centromere protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16319 Tuberculist Genomic Region	67492 zinc finger, AN1-type domain 4 Details for - - zinc finger, AN1-type domain 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67492 Tuberculist Genomic Region
69069 RIKEN cDNA 1810011H11 gene Details for - - RIKEN cDNA 1810011H11 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69069 Tuberculist Genomic Region	71085 Rho GTPase activating protein 19 Details for - - Rho GTPase activating protein 19 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71085 Tuberculist Genomic Region
17688 mutS homolog 6 (E. coli) Details for - - mutS homolog 6 (E. coli) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17688 Tuberculist Genomic Region	216445 Rho GTPase activating protein 9 Details for - - Rho GTPase activating protein 9 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216445 Tuberculist Genomic Region
227099 postmeiotic segregation increased 1 (S. cerevisiae) Details for - - postmeiotic segregation increased 1 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227099 Tuberculist Genomic Region	327762 DNA replication helicase 2 homolog (yeast) Details for - - DNA replication helicase 2 homolog (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 327762 Tuberculist Genomic Region
56424 STIP1 homology and U-Box containing protein 1 Details for - - STIP1 homology and U-Box containing protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56424 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_ZFX_01_M01593	0.941176	0.0000125

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000000012	WARAAANAARMA	NA	0.056	CCCCGCCCCNC	SP1_MA0079.2, Klf4_MA0039.2, SP1_MA0079.1, V$SP1_02_M01303, V$SP4_Q5_M01273, V$KLF7_03_M02773, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$GKLF_02_M01588, V$ZFP281_01_M01597, V$CKROX_Q2_M01175, V$SP1_Q4_01_M00932, V$MAZR_01_M00491, V$SP1_03_M02281, V$UF1H3BETA_Q6_M01068, V$GC_01_M00255, V$MAZ_Q6_M00649, V$BCL6B_04_M02844, V$ZFP281_04_M02831, V$CACD_01_M01113, V$KROX_Q6_M00982, V$ZNF219_01_M01122, V$KLF15_Q2_M01714, V$SMAD4_04_M02898, V$ZBP89_Q4_M01816, V$SP1_01_M00008, V$SP1SP3_Q4_M01219, V$SP2_01_M01783, V$ETF_Q6_M00695, V$FKLF_Q5_M01837, V$ZFP410_04_M02936, V$EKLF_Q5_M01874, V$E2F3_Q6_M02089, V$MAZ_Q6_01_M02023, V$NFE4_Q5_M02105, V$SP4_03_M02810, V$CACBINDINGPROTEIN_Q6_M00720, V$ZFP740_03_M02834, V$CACCCBINDINGFACTOR_Q6_M00721, V$EGR1_Q6_M01873, V$MZF1_01_M00083, Klf7.1, Bcl6b.2, Zfp281.2, Smad3.1, Zfp410.1, Sp4.1, Zfp740.1, Egr1.1, Ascl2.2, Sox13.2, ZNF740_C2H2_full_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, KLF14_C2H2_DBD_monomeric_14_1, FOXO6_forkhead_DBD_putatively-multimeric_14_1, KLF13_C2H2_full_monomeric_18_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.49	TCGCGG	NA	1.72	CTCGCGGT

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.56	TGCTAC	NA	NA	0.59	AGGTTGCT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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