TargetScan_158 megaCluster: 4 Residual: 0.28

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_158	4	0.28	14	0	0.837243	0

Members

Displaying 1 - 44 of 44

TFBS DB TF

TFs	percTargets	pValue
Sp4.1	1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000025	AAARRAAAAAAA	NA	0.0000011	RGKGGGCGGGGC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$SP1_03_M02281, V$SP1_Q6_01_M00931, V$GC_01_M00255, V$SP1_Q2_01_M00933, V$SP2_01_M01783, V$KLF7_03_M02773, V$MAZR_01_M00491, V$GKLF_02_M01588, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$SP4_03_M02810, V$ZNF219_01_M01122, V$SP1_02_M01303, V$CKROX_Q2_M01175, V$SMAD4_04_M02898, V$E2F3_Q6_M02089, V$SP1SP3_Q4_M01219, V$SP1_01_M00008, V$KROX_Q6_M00982, V$EGR_Q6_M00807, V$ZBP89_Q4_M01816, V$CACD_01_M01113, V$MAZ_Q6_01_M02023, V$ZFP740_03_M02834, V$EGR1_Q6_M01873, V$EKLF_Q5_M01874, V$MAZ_Q6_M00649, V$EGR1_06_M02744, V$CACBINDINGPROTEIN_Q6_M00720, V$ZFP281_04_M02831, V$WT1_Q6_01_M02036, V$FKLF_Q5_M01837, Klf7.1, Sp4.1, Smad3.1, Zfp740.1, Egr1.1, Zfp281.2, Sp4.2, Bcl6b.2, Zfp410.1, Ascl2.2, Zif268.1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, KLF14_C2H2_DBD_monomeric_14_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, KLF13_C2H2_full_monomeric_18_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, Zfp740_C2H2_DBD_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.31	CGGCGA	NA	1.53	CCGCCGGA	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.43	CGTGAG	NA	NA	0.56	AACTTGTT	mmu-mir-7a-2-3p, mmu-mir-7b-3p	7mer_a1

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-188-3p	0.65625	0.0000554

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-203	0.558824	0.000000549

100503785 insulin-like growth factor 1, intronic transcript Details for - - insulin-like growth factor 1, intronic transcript GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503785 Tuberculist Genomic Region	241621 predicted gene 13981 Details for - - predicted gene 13981 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241621 Tuberculist Genomic Region
52118 poliovirus receptor Details for - - poliovirus receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52118 Tuberculist Genomic Region	546695 ribosomal protein L12 pseudogene Details for - - ribosomal protein L12 pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 546695 Tuberculist Genomic Region
66580 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) Details for RP23-324H1.4 - ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66580 Tuberculist Genomic Region	71844 nucleoporin like 1 Details for - - nucleoporin like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71844 Tuberculist Genomic Region
74769 phosphatidylinositol 3-kinase, catalytic, beta polypeptide Details for - - phosphatidylinositol 3-kinase, catalytic, beta polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74769 Tuberculist Genomic Region	100040823 ribosomal protein L35 pseudogene Details for - - ribosomal protein L35 pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100040823 Tuberculist Genomic Region
100125262 T cell receptor beta, constant region 1 Details for - - T cell receptor beta, constant region 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100125262 Tuberculist Genomic Region	100503626 predicted gene, 19803 Details for - - predicted gene, 19803 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503626 Tuberculist Genomic Region
105722 anoctamin 6 Details for - - anoctamin 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 105722 Tuberculist Genomic Region	107513 signal sequence receptor, alpha Details for - - signal sequence receptor, alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107513 Tuberculist Genomic Region
110109 NOP2 nucleolar protein Details for - - NOP2 nucleolar protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110109 Tuberculist Genomic Region	16410 integrin alpha V Details for RP23-111F12.3 - integrin alpha V GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16410 Tuberculist Genomic Region
18442 purinergic receptor P2Y, G-protein coupled 2 Details for - - purinergic receptor P2Y, G-protein coupled 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18442 Tuberculist Genomic Region	19248 protein tyrosine phosphatase, non-receptor type 12 Details for - - protein tyrosine phosphatase, non-receptor type 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19248 Tuberculist Genomic Region
20375 spleen focus forming virus (SFFV) proviral integration oncogene Details for RP23-20F9.1 - spleen focus forming virus (SFFV) proviral integration oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20375 Tuberculist Genomic Region	22224 ubiquitin specific peptidase 10 Details for - - ubiquitin specific peptidase 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22224 Tuberculist Genomic Region
226169 peroxisome proliferative activated receptor, gamma, coactivator-related 1 Details for - - peroxisome proliferative activated receptor, gamma, coactivator-related 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226169 Tuberculist Genomic Region	244418 DNA segment, Chr 8, ERATO Doi 82, expressed Details for - - DNA segment, Chr 8, ERATO Doi 82, expressed GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 244418 Tuberculist Genomic Region
270118 mastermind like 2 (Drosophila) Details for - - mastermind like 2 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 270118 Tuberculist Genomic Region	331401 THO complex 2 Details for RP23-300D2.1 - THO complex 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 331401 Tuberculist Genomic Region
434394 ribosomal protein L36 pseudogene Details for - - ribosomal protein L36 pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 434394 Tuberculist Genomic Region	52857 GRAM domain containing 1A Details for - - GRAM domain containing 1A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52857 Tuberculist Genomic Region
54446 nuclear factor of activated T cells 5 Details for - - nuclear factor of activated T cells 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54446 Tuberculist Genomic Region	57753 nucleolar complex associated 3 homolog (S. cerevisiae) Details for - - nucleolar complex associated 3 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57753 Tuberculist Genomic Region
58182 prokineticin receptor 1 Details for - - prokineticin receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 58182 Tuberculist Genomic Region	67149 Na+/K+ transporting ATPase interacting 1 Details for - - Na+/K+ transporting ATPase interacting 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67149 Tuberculist Genomic Region
67263 zinc finger SWIM-type containing 6 Details for - - zinc finger SWIM-type containing 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67263 Tuberculist Genomic Region	70425 casein kinase 1, gamma 3 Details for - - casein kinase 1, gamma 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70425 Tuberculist Genomic Region
75901 DCP1 decapping enzyme homolog A (S. cerevisiae) Details for - - DCP1 decapping enzyme homolog A (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75901 Tuberculist Genomic Region	78825 desumoylating isopeptidase 2 Details for - - desumoylating isopeptidase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78825 Tuberculist Genomic Region
93736 AF4/FMR2 family, member 4 Details for RP23-226J16.7 - AF4/FMR2 family, member 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 93736 Tuberculist Genomic Region	109754 cytochrome b5 reductase 3 Details for - - cytochrome b5 reductase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109754 Tuberculist Genomic Region
231713 N(alpha)-acetyltransferase 25, NatB auxiliary subunit Details for - - N(alpha)-acetyltransferase 25, NatB auxiliary subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231713 Tuberculist Genomic Region	52348 vacuolar protein sorting 37A (yeast) Details for - - vacuolar protein sorting 37A (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52348 Tuberculist Genomic Region
18689 per-hexamer repeat gene 4 Details for - - per-hexamer repeat gene 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18689 Tuberculist Genomic Region	18787 serine (or cysteine) peptidase inhibitor, clade E, member 1 Details for - - serine (or cysteine) peptidase inhibitor, clade E, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18787 Tuberculist Genomic Region
192657 elongation factor RNA polymerase II 2 Details for - - elongation factor RNA polymerase II 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192657 Tuberculist Genomic Region	21353 TRAF family member-associated Nf-kappa B activator Details for RP23-1O11.1 - TRAF family member-associated Nf-kappa B activator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21353 Tuberculist Genomic Region
225929 protein associated with topoisomerase II homolog 1 (yeast) Details for - - protein associated with topoisomerase II homolog 1 (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225929 Tuberculist Genomic Region	53621 CCR4-NOT transcription complex, subunit 4 Details for - - CCR4-NOT transcription complex, subunit 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53621 Tuberculist Genomic Region
67154 metadherin Details for - - metadherin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67154 Tuberculist Genomic Region	68473 MOB kinase activator 1B Details for - - MOB kinase activator 1B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68473 Tuberculist Genomic Region

TargetScan_158 megaCluster: 4 Residual: 0.28

Summary

Members

Details for - - insulin-like growth factor 1, intronic transcript

Details for - - predicted gene 13981

Details for - - poliovirus receptor

Details for - - ribosomal protein L12 pseudogene

Details for RP23-324H1.4 - ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)

Details for - - nucleoporin like 1

Details for - - phosphatidylinositol 3-kinase, catalytic, beta polypeptide

Details for - - ribosomal protein L35 pseudogene

Details for - - T cell receptor beta, constant region 1

Details for - - predicted gene, 19803

Details for - - anoctamin 6

Details for - - signal sequence receptor, alpha

Details for - - NOP2 nucleolar protein

Details for RP23-111F12.3 - integrin alpha V

Details for - - purinergic receptor P2Y, G-protein coupled 2

Details for - - protein tyrosine phosphatase, non-receptor type 12

Details for RP23-20F9.1 - spleen focus forming virus (SFFV) proviral integration oncogene

Details for - - ubiquitin specific peptidase 10

Details for - - peroxisome proliferative activated receptor, gamma, coactivator-related 1

Details for - - DNA segment, Chr 8, ERATO Doi 82, expressed

Details for - - mastermind like 2 (Drosophila)

Details for RP23-300D2.1 - THO complex 2

Details for - - ribosomal protein L36 pseudogene

Details for - - GRAM domain containing 1A

Details for - - nuclear factor of activated T cells 5

Details for - - nucleolar complex associated 3 homolog (S. cerevisiae)

Details for - - prokineticin receptor 1

Details for - - Na+/K+ transporting ATPase interacting 1

Details for - - zinc finger SWIM-type containing 6

Details for - - casein kinase 1, gamma 3

Details for - - DCP1 decapping enzyme homolog A (S. cerevisiae)

Details for - - desumoylating isopeptidase 2

Details for RP23-226J16.7 - AF4/FMR2 family, member 4

Details for - - cytochrome b5 reductase 3

Details for - - N(alpha)-acetyltransferase 25, NatB auxiliary subunit

Details for - - vacuolar protein sorting 37A (yeast)

Details for - - per-hexamer repeat gene 4

Details for - - serine (or cysteine) peptidase inhibitor, clade E, member 1

Details for - - elongation factor RNA polymerase II 2

Details for RP23-1O11.1 - TRAF family member-associated Nf-kappa B activator

Details for - - protein associated with topoisomerase II homolog 1 (yeast)

Details for - - CCR4-NOT transcription complex, subunit 4

Details for - - metadherin

Details for - - MOB kinase activator 1B

GO Terms

3p UTR PITA