TargetScan_187 megaCluster: 4 Residual: 0.17

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_187	4	0.17	9	0	0.748207	0.113

Members

Displaying 1 - 42 of 42

TFBS DB TF

TFs	percTargets	pValue
Egr1.2	0.6	0.0000215

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000025	TYTKTTTTTYT	NA	15000	GKGGGMGGGGC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_03_M02281, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$SP1_Q4_01_M00932, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$GC_01_M00255, V$CKROX_Q2_M01175, V$GKLF_02_M01588, V$MAZR_01_M00491, V$ZNF219_01_M01122, V$KLF7_03_M02773, V$SP1_02_M01303, V$MAZ_Q6_01_M02023, V$ZBP89_Q4_M01816, V$SP2_01_M01783, V$MAZ_Q6_M00649, V$EGR1_Q6_M01873, V$ZFP281_04_M02831, V$CACD_01_M01113, V$KROX_Q6_M00982, V$SP4_03_M02810, V$SP1SP3_Q4_M01219, V$EGR1_06_M02744, V$SP1_01_M00008, V$EGR_Q6_M00807, V$ETF_Q6_M00695, V$CACBINDINGPROTEIN_Q6_M00720, V$SMAD4_04_M02898, V$ZFP740_03_M02834, V$EKLF_Q5_M01874, V$MZF1_02_M00084, V$E2F3_Q6_M02089, V$KLF15_Q2_M01714, V$WT1_Q6_01_M02036, V$BCL6B_04_M02844, V$FKLF_Q5_M01837, V$WT1_Q6_M01118, V$ZFP410_04_M02936, V$EGR1_02_M01972, V$FPM315_01_M01587, V$NGFIC_01_M00244, Klf7.1, Zfp281.2, Sp4.1, Egr1.1, Zfp740.1, Smad3.1, Zif268.1, Bcl6b.2, Zfp410.1, Ascl2.2, Sp4.2, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, ZNF740_C2H2_full_monomeric_10_1, KLF14_C2H2_DBD_monomeric_14_1, Zfp740_C2H2_DBD_monomeric_10_1, Klf12_C2H2_DBD_monomeric_15_1, KLF13_C2H2_full_monomeric_18_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.08	CGCGAG	NA	1.17	NTCGGCGC	E2F2.2, E2F3.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.68	NGAGANGG	mmu-mir-340-3p	7mer_a1		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-875-3p	0.733333	0.0000537

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-582-5p	0.428571	0.0000414

235584 dual specificity phosphatase 7 Details for - - dual specificity phosphatase 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 235584 Tuberculist Genomic Region	319953 tubulin tyrosine ligase-like 1 Details for RP23-10K12.1 - tubulin tyrosine ligase-like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 319953 Tuberculist Genomic Region
93691 Kruppel-like factor 7 (ubiquitous) Details for RP23-23D16.1 - Kruppel-like factor 7 (ubiquitous) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 93691 Tuberculist Genomic Region	101023 predicted gene, 20169 Details for - - predicted gene, 20169 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504320 Tuberculist Genomic Region
11813 zinc finger protein 513 Details for - - zinc finger protein 513 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 101023 Tuberculist Genomic Region	13424 apolipoprotein C-II Details for - - apolipoprotein C-II GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11813 Tuberculist Genomic Region
14123 dynein cytoplasmic 1 heavy chain 1 Details for - - dynein cytoplasmic 1 heavy chain 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13424 Tuberculist Genomic Region	14182 fibrosin Details for - - fibrosin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14123 Tuberculist Genomic Region
16323 fibroblast growth factor receptor 1 Details for - - fibroblast growth factor receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14182 Tuberculist Genomic Region	16798 inhibin beta-A Details for - - inhibin beta-A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16323 Tuberculist Genomic Region
17127 large tumor suppressor Details for - - large tumor suppressor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16798 Tuberculist Genomic Region	192195 SMAD family member 3 Details for RP23-63E8.1 - SMAD family member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17127 Tuberculist Genomic Region
19697 ash1 (absent, small, or homeotic)-like (Drosophila) Details for - - ash1 (absent, small, or homeotic)-like (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 192195 Tuberculist Genomic Region	20544 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Details for - - v-rel reticuloendotheliosis viral oncogene homolog A (avian) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19697 Tuberculist Genomic Region
20602 solute carrier family 9 (sodium/hydrogen exchanger), member 1 Details for RP23-32C12.6 - solute carrier family 9 (sodium/hydrogen exchanger), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20544 Tuberculist Genomic Region	216874 nuclear receptor co-repressor 2 Details for - - nuclear receptor co-repressor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20602 Tuberculist Genomic Region
21859 calmodulin binding transcription activator 2 Details for DN-183N8.19-006 - calmodulin binding transcription activator 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216874 Tuberculist Genomic Region	223435 tissue inhibitor of metalloproteinase 3 Details for - - tissue inhibitor of metalloproteinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21859 Tuberculist Genomic Region
23983 triple functional domain (PTPRF interacting) Details for - - triple functional domain (PTPRF interacting) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223435 Tuberculist Genomic Region	24045 poly(rC) binding protein 1 Details for - - poly(rC) binding protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23983 Tuberculist Genomic Region
384281 secretory carrier membrane protein 3 Details for - - secretory carrier membrane protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24045 Tuberculist Genomic Region	52348 glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial) Details for - - glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 384281 Tuberculist Genomic Region
69538 vacuolar protein sorting 37A (yeast) Details for - - vacuolar protein sorting 37A (yeast) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52348 Tuberculist Genomic Region	71398 anthrax toxin receptor 1 Details for - - anthrax toxin receptor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69538 Tuberculist Genomic Region
71844 RIKEN cDNA 5430427O19 gene Details for RP23-311G7.1 - RIKEN cDNA 5430427O19 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71398 Tuberculist Genomic Region	72472 nucleoporin like 1 Details for - - nucleoporin like 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71844 Tuberculist Genomic Region
72958 solute carrier family 16 (monocarboxylic acid transporters), member 10 Details for - - solute carrier family 16 (monocarboxylic acid transporters), member 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72472 Tuberculist Genomic Region	76551 zinc finger protein 493 Details for - - zinc finger protein 493 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72958 Tuberculist Genomic Region
78943 coiled-coil domain containing 6 Details for - - coiled-coil domain containing 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76551 Tuberculist Genomic Region	83925 endoplasmic reticulum (ER) to nucleus signalling 1 Details for RP23-418O11.11-001 - endoplasmic reticulum (ER) to nucleus signalling 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78943 Tuberculist Genomic Region
99334 trichorhinophalangeal syndrome I (human) Details for - - trichorhinophalangeal syndrome I (human) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 83925 Tuberculist Genomic Region	12153 zinc finger SCAN domains 29 Details for RP23-232N20.4 - zinc finger SCAN domains 29 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99334 Tuberculist Genomic Region
18036 bone morphogenetic protein 1 Details for - - bone morphogenetic protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12153 Tuberculist Genomic Region	108960 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18036 Tuberculist Genomic Region
14289 interleukin-1 receptor-associated kinase 2 Details for - - interleukin-1 receptor-associated kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108960 Tuberculist Genomic Region	16365 formyl peptide receptor 2 Details for - - formyl peptide receptor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14289 Tuberculist Genomic Region
320207 immunoresponsive gene 1 Details for - - immunoresponsive gene 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16365 Tuberculist Genomic Region	21923 phosphoinositide-3-kinase, regulatory subunit 5, p101 Details for RP23-432M23.2 - phosphoinositide-3-kinase, regulatory subunit 5, p101 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320207 Tuberculist Genomic Region
67154 tenascin C Details for RP24-144L11.1 - tenascin C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21923 Tuberculist Genomic Region	68473 metadherin Details for - - metadherin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67154 Tuberculist Genomic Region
100502606 MOB kinase activator 1B Details for - - MOB kinase activator 1B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68473 Tuberculist Genomic Region	Details for - - predicted gene, 19279 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100502606 Tuberculist Genomic Region

TargetScan_187 megaCluster: 4 Residual: 0.17

Summary

Members

Details for - - dual specificity phosphatase 7

Details for RP23-10K12.1 - tubulin tyrosine ligase-like 1

Details for RP23-23D16.1 - Kruppel-like factor 7 (ubiquitous)

Details for - - predicted gene, 20169

Details for - - zinc finger protein 513

Details for - - apolipoprotein C-II

Details for - - dynein cytoplasmic 1 heavy chain 1

Details for - - fibrosin

Details for - - fibroblast growth factor receptor 1

Details for - - inhibin beta-A

Details for - - large tumor suppressor

Details for RP23-63E8.1 - SMAD family member 3

Details for - - ash1 (absent, small, or homeotic)-like (Drosophila)

Details for - - v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Details for RP23-32C12.6 - solute carrier family 9 (sodium/hydrogen exchanger), member 1

Details for - - nuclear receptor co-repressor 2

Details for DN-183N8.19-006 - calmodulin binding transcription activator 2

Details for - - tissue inhibitor of metalloproteinase 3

Details for - - triple functional domain (PTPRF interacting)

Details for - - poly(rC) binding protein 1

Details for - - secretory carrier membrane protein 3

Details for - - glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial)

Details for - - vacuolar protein sorting 37A (yeast)

Details for - - anthrax toxin receptor 1

Details for RP23-311G7.1 - RIKEN cDNA 5430427O19 gene

Details for - - nucleoporin like 1

Details for - - solute carrier family 16 (monocarboxylic acid transporters), member 10

Details for - - zinc finger protein 493

Details for - - coiled-coil domain containing 6

Details for RP23-418O11.11-001 - endoplasmic reticulum (ER) to nucleus signalling 1

Details for - - trichorhinophalangeal syndrome I (human)

Details for RP23-232N20.4 - zinc finger SCAN domains 29

Details for - - bone morphogenetic protein 1

Details for - - nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

Details for - - interleukin-1 receptor-associated kinase 2

Details for - - formyl peptide receptor 2

Details for - - immunoresponsive gene 1

Details for RP23-432M23.2 - phosphoinositide-3-kinase, regulatory subunit 5, p101

Details for RP24-144L11.1 - tenascin C

Details for - - metadherin

Details for - - MOB kinase activator 1B

Details for - - predicted gene, 19279

GO Terms

3p UTR PITA