TargetScan_226 megaCluster: 11 Residual: 0.27 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_226	11	0.27	15	0	0.85162	0

Members

Displaying 1 - 35 of 35

20887 sulfotransferase family 1A, phenol-preferring, member 1 Details for - - sulfotransferase family 1A, phenol-preferring, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20887 Tuberculist Genomic Region	71865 F-box protein 30 Details for - - F-box protein 30 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71865 Tuberculist Genomic Region
103080 septin 10 Details for - - septin 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 103080 Tuberculist Genomic Region	14645 glutamate-ammonia ligase (glutamine synthetase) Details for - - glutamate-ammonia ligase (glutamine synthetase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14645 Tuberculist Genomic Region
15468 protein arginine N-methyltransferase 2 Details for - - protein arginine N-methyltransferase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15468 Tuberculist Genomic Region	16952 annexin A1 Details for - - annexin A1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16952 Tuberculist Genomic Region
20719 serine (or cysteine) peptidase inhibitor, clade B, member 6a Details for RP23-262J21.1 - serine (or cysteine) peptidase inhibitor, clade B, member 6a GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20719 Tuberculist Genomic Region	20916 succinate-Coenzyme A ligase, ADP-forming, beta subunit Details for - - succinate-Coenzyme A ligase, ADP-forming, beta subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20916 Tuberculist Genomic Region
21780 transcription factor A, mitochondrial Details for - - transcription factor A, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21780 Tuberculist Genomic Region	231329 polymerase (RNA) II (DNA directed) polypeptide B Details for - - polymerase (RNA) II (DNA directed) polypeptide B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231329 Tuberculist Genomic Region
233870 Tu translation elongation factor, mitochondrial Details for - - Tu translation elongation factor, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233870 Tuberculist Genomic Region	235281 sodium channel, voltage-gated, type III, beta Details for - - sodium channel, voltage-gated, type III, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 235281 Tuberculist Genomic Region
236539 3-phosphoglycerate dehydrogenase Details for - - 3-phosphoglycerate dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236539 Tuberculist Genomic Region	24014 ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) Details for - - ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24014 Tuberculist Genomic Region
245670 Ras-related GTP binding B Details for RP23-180D16.3 - Ras-related GTP binding B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245670 Tuberculist Genomic Region	319322 splicing factor 3b, subunit 2 Details for - - splicing factor 3b, subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 319322 Tuberculist Genomic Region
330050 family with sequence similarity 185, member A Details for - - family with sequence similarity 185, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 330050 Tuberculist Genomic Region	54405 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 Details for RP23-43O20.5 - NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54405 Tuberculist Genomic Region
56350 ADP-ribosylation factor-like 3 Details for - - ADP-ribosylation factor-like 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56350 Tuberculist Genomic Region	66156 anaphase promoting complex subunit 11 Details for RP23-84C12.5 - anaphase promoting complex subunit 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66156 Tuberculist Genomic Region
66818 small integral membrane protein 7 Details for - - small integral membrane protein 7 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66818 Tuberculist Genomic Region	67143 IKAROS family zinc finger 5 Details for - - IKAROS family zinc finger 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67143 Tuberculist Genomic Region
67247 mitochondrial amidoxime reducing component 2 Details for - - mitochondrial amidoxime reducing component 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67247 Tuberculist Genomic Region	67466 phosducin-like Details for RP23-464H12.4 - phosducin-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67466 Tuberculist Genomic Region
67515 tetratricopeptide repeat domain 33 Details for - - tetratricopeptide repeat domain 33 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67515 Tuberculist Genomic Region	67608 nuclear prelamin A recognition factor Details for RP23-349B15.5 - nuclear prelamin A recognition factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67608 Tuberculist Genomic Region
67976 TraB domain containing Details for - - TraB domain containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67976 Tuberculist Genomic Region	72655 small nucleolar RNA host gene 5 Details for - - small nucleolar RNA host gene 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72655 Tuberculist Genomic Region
73419 RIKEN cDNA 1700052N19 gene Details for - - RIKEN cDNA 1700052N19 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73419 Tuberculist Genomic Region	75619 FAST kinase domains 2 Details for - - FAST kinase domains 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75619 Tuberculist Genomic Region
76547 transmembrane protein 101 Details for RP23-167N11.1 - transmembrane protein 101 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76547 Tuberculist Genomic Region	76863 DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) Details for - - DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76863 Tuberculist Genomic Region
97122 histone cluster 2, H4 Details for - - histone cluster 2, H4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 97122 Tuberculist Genomic Region	99152 anaphase promoting complex subunit 2 Details for RP23-132N23.17-001 - anaphase promoting complex subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 99152 Tuberculist Genomic Region
226646 NADH dehydrogenase (ubiquinone) Fe-S protein 2 Details for - - NADH dehydrogenase (ubiquinone) Fe-S protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226646 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
NA

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000033	CTTTYTNTTTM	IRF1_MA0050.1, V$IRF2_Q6_M01882, V$IRF_Q6_01_M00972	110	GGCCCCGCCCNC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_Q4_01_M00932, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_03_M02281, V$SP1_Q2_01_M00933, V$GC_01_M00255, V$KLF7_03_M02773, V$GKLF_02_M01588, V$UF1H3BETA_Q6_M01068, V$MAZR_01_M00491, V$SP4_03_M02810, V$SP1_02_M01303, V$SP2_01_M01783, V$ZFP281_01_M01597, V$ZNF219_01_M01122, V$EGR1_Q6_M01873, V$KROX_Q6_M00982, V$ZBP89_Q4_M01816, V$E2F3_Q6_M02089, V$EGR_Q6_M00807, V$CKROX_Q2_M01175, V$SMAD4_04_M02898, V$EGR1_06_M02744, V$EKLF_Q5_M01874, V$CACD_01_M01113, V$SP1SP3_Q4_M01219, V$MAZ_Q6_01_M02023, V$ZFP740_03_M02834, V$ZFP281_04_M02831, V$CACBINDINGPROTEIN_Q6_M00720, V$SP1_01_M00008, V$CNOT3_01_M01253, Klf7.1, Sp4.1, Egr1.1, Smad3.1, Zfp740.1, Zif268.1, Zfp281.2, Sp4.2, Bcl6b.2, Zfp410.1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, Klf12_C2H2_DBD_monomeric_15_1, SP8_C2H2_DBD_monomeric_12_1, SP3_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.24	ATCGCG	NA	1.41	CGCGATTC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.43	GTTAGG	NA	NA	0.61	NNAGTTAG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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