TargetScan_34 megaCluster: 4 Residual: 0.22 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_34	4	0.22	15	0	0.912652	0

Members

Displaying 1 - 34 of 34

11977 ATPase, Cu++ transporting, alpha polypeptide Details for RP23-186F4.3 - ATPase, Cu++ transporting, alpha polypeptide GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11977 Tuberculist Genomic Region	14962 complement factor B Details for RP24-317H19.4 - complement factor B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14962 Tuberculist Genomic Region
14990 histocompatibility 2, M region locus 2 Details for - - histocompatibility 2, M region locus 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14990 Tuberculist Genomic Region	16408 integrin alpha L Details for - - integrin alpha L GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16408 Tuberculist Genomic Region
17254 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Details for - - solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17254 Tuberculist Genomic Region	17390 matrix metallopeptidase 2 Details for - - matrix metallopeptidase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17390 Tuberculist Genomic Region
194744 solute carrier family 25, member 43 Details for RP23-100G16.4 - solute carrier family 25, member 43 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 194744 Tuberculist Genomic Region	20555 schlafen 1 Details for RP23-308N3.1 - schlafen 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20555 Tuberculist Genomic Region
20773 serine palmitoyltransferase, long chain base subunit 2 Details for - - serine palmitoyltransferase, long chain base subunit 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20773 Tuberculist Genomic Region	22259 nuclear receptor subfamily 1, group H, member 3 Details for RP23-20F9.5 - nuclear receptor subfamily 1, group H, member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22259 Tuberculist Genomic Region
233575 post-GPI attachment to proteins 2 Details for - - post-GPI attachment to proteins 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233575 Tuberculist Genomic Region	233781 xylosyltransferase 1 Details for - - xylosyltransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233781 Tuberculist Genomic Region
27081 zinc finger protein 275 Details for RP23-95K12.3 - zinc finger protein 275 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27081 Tuberculist Genomic Region	433956 HEAT repeat containing 2 Details for - - HEAT repeat containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 433956 Tuberculist Genomic Region
50721 sirtuin 6 Details for - - sirtuin 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50721 Tuberculist Genomic Region	641340 nuclear receptor binding factor 2 Details for - - nuclear receptor binding factor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 641340 Tuberculist Genomic Region
64380 membrane-spanning 4-domains, subfamily A, member 4C Details for - - membrane-spanning 4-domains, subfamily A, member 4C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 64380 Tuberculist Genomic Region	66168 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) Details for - - glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66168 Tuberculist Genomic Region
68836 mitochondrial ribosomal protein L52 Details for - - mitochondrial ribosomal protein L52 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68836 Tuberculist Genomic Region	69774 membrane-spanning 4-domains, subfamily A, member 6B Details for - - membrane-spanning 4-domains, subfamily A, member 6B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69774 Tuberculist Genomic Region
70785 DENN/MADD domain containing 1C Details for - - DENN/MADD domain containing 1C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70785 Tuberculist Genomic Region	74440 c-Maf inducing protein Details for - - c-Maf inducing protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74440 Tuberculist Genomic Region
94352 lysyl oxidase-like 2 Details for - - lysyl oxidase-like 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 94352 Tuberculist Genomic Region	100038548 predicted gene 10521 Details for - - predicted gene 10521 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100038548 Tuberculist Genomic Region
100503460 predicted gene, 19705 Details for - - predicted gene, 19705 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100503460 Tuberculist Genomic Region	170625 sorting nexin 18 Details for - - sorting nexin 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170625 Tuberculist Genomic Region
170744 toll-like receptor 8 Details for RP23-139P21.2 - toll-like receptor 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170744 Tuberculist Genomic Region	17281 FYVE and coiled-coil domain containing 1 Details for - - FYVE and coiled-coil domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17281 Tuberculist Genomic Region
21416 transcription factor 7 like 2, T cell specific, HMG box Details for - - transcription factor 7 like 2, T cell specific, HMG box GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21416 Tuberculist Genomic Region	223774 asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase) Details for - - asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 223774 Tuberculist Genomic Region
226695 interferon activated gene 205 Details for - - interferon activated gene 205 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226695 Tuberculist Genomic Region	240921 predicted gene 4955 Details for - - predicted gene 4955 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240921 Tuberculist Genomic Region
665317 component of Sp100-rs pseudogene Details for - - component of Sp100-rs pseudogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 665317 Tuberculist Genomic Region	114644 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 Details for RP23-395E18.3 - solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 114644 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
IRF9_IRF_full_trimeric_15_1	0.344828	0.000000885

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
4.9	CCCCRCCCWC	Klf4_MA0039.2, SP1_MA0079.2, V$SP1_Q2_01_M00933, V$ZFP281_01_M01597, V$GKLF_02_M01588, V$SP4_Q5_M01273, V$SP1_Q4_01_M00932, V$UF1H3BETA_Q6_M01068, V$SP1_03_M02281, V$KLF7_03_M02773, V$SP1_Q6_01_M00931, V$SP1_Q6_M00196, V$SP1_02_M01303, V$GC_01_M00255, V$CKROX_Q2_M01175, V$CACD_01_M01113, V$EKLF_Q5_M01874, V$MAZR_01_M00491, V$MAZ_Q6_M00649, V$ZNF219_01_M01122, V$CACCCBINDINGFACTOR_Q6_M00721, V$MAZ_Q6_01_M02023, V$EGR1_Q6_M01873, V$EGR1_06_M02744, V$NGFIC_01_M00244, V$ZBP89_Q4_M01816, V$ZFP281_04_M02831, V$KROX_Q6_M00982, V$EGR1_02_M01972, V$SP2_01_M01783, V$GLI3_Q5_01_M01657, V$SP1SP3_Q4_M01219, V$SP4_03_M02810, V$CACBINDINGPROTEIN_Q6_M00720, V$E2F3_Q6_M02089, V$ZFP740_03_M02834, V$EGR_Q6_M00807, V$SP1_01_M00008, V$MZF1_01_M00083, V$WT1_Q6_M01118, V$SP3_Q3_M00665, V$EGR1_01_M00243, Klf7.1, Egr1.1, Zfp281.2, Sp4.1, Zfp740.1, Zif268.1, Smad3.1, Ascl2.2, Sox13.2, Bcl6b.2, ZNF740_C2H2_full_monomeric_10_1, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1, Zfp740_C2H2_DBD_monomeric_10_1, KLF14_C2H2_DBD_monomeric_14_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1, EGR2_C2H2_full_monomeric_15_1	38	WNTTTCTNTST	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
0.88	CGGGGT	Klf7.1	1.03	CCGGCNCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.58	CGATCG	NA	NA	0.69	CCNGCTCN	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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