Nr1h3 nuclear receptor subfamily 1, group H, member 3 (22259) | Macrophage Network Portal

Summary

	Symbol	Product	Feature Type	Strand	Chr
22259	Nr1h3	nuclear receptor subfamily 1, group H, member 3	protein-coding		2

Synonyms

Synonyms
AU018371 \| LXR \| RLD1 \| Unr1

DB XRef

Ensembl	MGI	VEGA
ENSMUSG00000002108	MGI:1352462	OTTMUSG00000014415

GO Terms

GO ID	Category	Definition	Evidence
GO:0000122 GO:0000790 GO:0003677 GO:0003700 GO:0003707 GO:0004879 GO:0005515 GO:0005634 GO:0005737 GO:0006351 GO:0006355 GO:0006366 GO:0006633 GO:0008270 GO:0010867 GO:0010870 GO:0010875 GO:0010887 GO:0030522 GO:0032270 GO:0032369 GO:0032376 GO:0032570 GO:0032810 GO:0034145 GO:0042632 GO:0043031 GO:0043277 GO:0043401 GO:0043565 GO:0044212 GO:0044255 GO:0045723 GO:0045861 GO:0045892 GO:0045893 GO:0045944 GO:0046872 GO:0046965 GO:0046982 GO:0048550 GO:0050728 GO:0051006 GO:0055088 GO:0055092 GO:0070328 GO:0071222 GO:0090188 GO:0090341 GO:2000189	Process Component Function	negative regulation of transcription from RNA polymerase II promoter nuclear chromatin DNA binding sequence-specific DNA binding transcription factor activity steroid hormone receptor activity ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity protein binding nucleus cytoplasm transcription, DNA-templated regulation of transcription, DNA-templated transcription from RNA polymerase II promoter fatty acid biosynthetic process zinc ion binding positive regulation of triglyceride biosynthetic process positive regulation of receptor biosynthetic process positive regulation of cholesterol efflux negative regulation of cholesterol storage intracellular receptor signaling pathway positive regulation of cellular protein metabolic process negative regulation of lipid transport positive regulation of cholesterol transport response to progesterone sterol response element binding positive regulation of toll-like receptor 4 signaling pathway cholesterol homeostasis negative regulation of macrophage activation apoptotic cell clearance steroid hormone mediated signaling pathway sequence-specific DNA binding transcription regulatory region DNA binding cellular lipid metabolic process positive regulation of fatty acid biosynthetic process negative regulation of proteolysis negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter metal ion binding retinoid X receptor binding protein heterodimerization activity negative regulation of pinocytosis negative regulation of inflammatory response positive regulation of lipoprotein lipase activity lipid homeostasis sterol homeostasis triglyceride homeostasis cellular response to lipopolysaccharide negative regulation of pancreatic juice secretion negative regulation of secretion of lysosomal enzymes positive regulation of cholesterol homeostasis	IDA ISO IEA IPI TAS IGI IMP

Regulatory Modules

	Motif 1	Motif 2	Residual
PITA_1 \| PITA_1 Residual: 0.26			0.26
PITA_224 \| PITA_224 Residual: 0.20			0.20
PITA_48 \| PITA_48 Residual: 0.33			0.33
TargetScan_120 \| TargetScan_120 Residual: 0.29			0.29
TargetScan_34 \| TargetScan_34 Residual: 0.22			0.22

Regulation

Displaying 1 - 5 of 5

Regulator Locus	Interaction	Weight

String Network

Entrez ID	STRINGS Network
STRING

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