PITA_176 megaCluster: 11 Residual: 0.12 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_176	11	0.12	15	0	0.974533	0

Members

Displaying 1 - 19 of 19

26411 mitogen-activated protein kinase kinase kinase kinase 1 Details for - - mitogen-activated protein kinase kinase kinase kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26411 Tuberculist Genomic Region	27360 adducin 3 (gamma) Details for - - adducin 3 (gamma) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27360 Tuberculist Genomic Region
28030 G elongation factor, mitochondrial 1 Details for - - G elongation factor, mitochondrial 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 28030 Tuberculist Genomic Region	66154 transmembrane protein 14C Details for - - transmembrane protein 14C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66154 Tuberculist Genomic Region
75317 PARP1 binding protein Details for - - PARP1 binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75317 Tuberculist Genomic Region	16906 RAB27A, member RAS oncogene family Details for - - RAB27A, member RAS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11891 Tuberculist Genomic Region
18247 lamin B1 Details for - - lamin B1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16906 Tuberculist Genomic Region	19357 ornithine decarboxylase antizyme 2 Details for - - ornithine decarboxylase antizyme 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18247 Tuberculist Genomic Region
20833 RAD21 homolog (S. pombe) Details for - - RAD21 homolog (S. pombe) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19357 Tuberculist Genomic Region	21335 structure specific recognition protein 1 Details for RP23-232L15.5 - structure specific recognition protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20833 Tuberculist Genomic Region
22142 transforming, acidic coiled-coil containing protein 3 Details for - - transforming, acidic coiled-coil containing protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21335 Tuberculist Genomic Region	230098 tubulin, alpha 1A Details for - - tubulin, alpha 1A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22142 Tuberculist Genomic Region
320204 Rho guanine nucleotide exchange factor (GEF) 39 Details for RP23-195K8.7 - Rho guanine nucleotide exchange factor (GEF) 39 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 230098 Tuberculist Genomic Region	68971 methyltransferase like 20 Details for RP23-355N5.5 - methyltransferase like 20 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320204 Tuberculist Genomic Region
70551 TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) Details for - - TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68971 Tuberculist Genomic Region	72183 transmembrane and tetratricopeptide repeat containing 4 Details for - - transmembrane and tetratricopeptide repeat containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70551 Tuberculist Genomic Region
74470 sorting nexin 6 Details for - - sorting nexin 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72183 Tuberculist Genomic Region	78767 centrosomal protein 72 Details for - - centrosomal protein 72 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74470 Tuberculist Genomic Region
Details for - - EF-hand calcium binding domain 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 78767 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
OTX2_homeodomain_DBD_dimeric_15_1	0.210526	0.000000184

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
2.1	TGTKTKYTTTYT	FOXC1_forkhead_DBD_dimeric_13_1, FOXC2_forkhead_DBD_dimeric_11_1	1.2	TTNNAAATGNA	NA

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.2	CGCGAC	Zfp161.2, Max.2	1.45	GCGCGNCT	Zfp161.2, E2F2.1, E2F3.1, Sp4.2, Zfp161.1

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.58	CGGCGG	NA	NA	1.03	TAANGCGC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-1-2-as	0.764706	0.0000247

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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