PITA_198 megaCluster: 8 Residual: 0.21

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_198	8	0.21	15	0	0.925334	0

Members

Displaying 1 - 47 of 47

TFBS DB TF

TFs	percTargets	pValue
V_SP1_Q6_01_M00931	0.978261	0.00000614

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000000000047	AAAAAAAAAANA	NA	11	NRGCCCCGCCCC	SP1_MA0079.2, Klf4_MA0039.2, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$GC_01_M00255, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$SP1_Q2_01_M00933, V$SP2_01_M01783, V$KLF7_03_M02773, V$SP1_03_M02281, V$MAZR_01_M00491, V$SP1_02_M01303, V$SMAD4_04_M02898, V$SP4_03_M02810, V$BCL6B_04_M02844, V$E2F3_Q6_M02089, V$CKROX_Q2_M01175, V$SP1_01_M00008, V$GKLF_02_M01588, V$ZFP410_04_M02936, V$SP4_04_M02914, V$KROX_Q6_M00982, V$ZFP281_01_M01597, V$UF1H3BETA_Q6_M01068, V$ETF_Q6_M00695, V$EGR1_Q6_M01873, V$ZBP89_Q4_M01816, V$EGR1_06_M02744, V$MAZ_Q6_M00649, V$ZFP740_03_M02834, V$FKLF_Q5_M01837, V$ASCL2_04_M02841, V$ZFP281_04_M02831, V$MAZ_Q6_01_M02023, V$CACD_01_M01113, V$EGR_Q6_M00807, V$E2F_Q2_M00803, Klf7.1, Sp4.1, Smad3.1, Bcl6b.2, Zfp410.1, Egr1.1, Sp4.2, Zfp281.2, Zfp740.1, Ascl2.2, Zif268.1, Sox13.2, Glis2.1, Klf7.2, SP4_C2H2_full_monomeric_17_1, SP1_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, KLF16_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, SP3_C2H2_DBD_monomeric_11_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.15	GGTCGC	NA	1.19	CGGCGCTN	E2F2.2, E2F3.2

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.48	ACGCGT	NA	NA	0.47	TATCCCNG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-409-5p	0.552632	0.00000781

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

101185 protection of telomeres 1A Details for - - protection of telomeres 1A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 101185 Tuberculist Genomic Region	109145 GINS complex subunit 4 (Sld5 homolog) Details for - - GINS complex subunit 4 (Sld5 homolog) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109145 Tuberculist Genomic Region
109299 RIKEN cDNA C330006A16 gene Details for - - RIKEN cDNA C330006A16 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109299 Tuberculist Genomic Region	110078 brain glycogen phosphorylase Details for RP23-241M12.1 - brain glycogen phosphorylase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110078 Tuberculist Genomic Region
16865 eukaryotic translation initiation factor 2D Details for - - eukaryotic translation initiation factor 2D GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16865 Tuberculist Genomic Region	17346 MAP kinase-interacting serine/threonine kinase 1 Details for RP23-374N19.2 - MAP kinase-interacting serine/threonine kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17346 Tuberculist Genomic Region
20598 sphingomyelin phosphodiesterase 2, neutral Details for - - sphingomyelin phosphodiesterase 2, neutral GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20598 Tuberculist Genomic Region	207425 WD repeat domain 11 Details for - - WD repeat domain 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 207425 Tuberculist Genomic Region
214895 lectin, mannose-binding 2-like Details for - - lectin, mannose-binding 2-like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 214895 Tuberculist Genomic Region	216011 leucine rich repeat containing 20 Details for - - leucine rich repeat containing 20 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216011 Tuberculist Genomic Region
216829 membrane magnesium transporter 2 Details for - - membrane magnesium transporter 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216829 Tuberculist Genomic Region	218215 ring finger protein 144B Details for - - ring finger protein 144B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 218215 Tuberculist Genomic Region
219144 ADP-ribosylation factor-like 11 Details for - - ADP-ribosylation factor-like 11 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 219144 Tuberculist Genomic Region	22718 zinc finger protein 60 Details for - - zinc finger protein 60 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22718 Tuberculist Genomic Region
229615 protein inhibitor of activated STAT 3 Details for - - protein inhibitor of activated STAT 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 229615 Tuberculist Genomic Region	231279 GUF1 GTPase homolog (S. cerevisiae) Details for - - GUF1 GTPase homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231279 Tuberculist Genomic Region
233204 TBC1 domain family, member 17 Details for - - TBC1 domain family, member 17 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 233204 Tuberculist Genomic Region	240034 zinc finger protein 760 Details for - - zinc finger protein 760 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 240034 Tuberculist Genomic Region
30838 F-box and WD-40 domain protein 4 Details for - - F-box and WD-40 domain protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30838 Tuberculist Genomic Region	381062 ER membrane associated RNA degradation Details for - - ER membrane associated RNA degradation GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381062 Tuberculist Genomic Region
50753 F-box protein 8 Details for - - F-box protein 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 50753 Tuberculist Genomic Region	53330 vesicle-associated membrane protein 4 Details for - - vesicle-associated membrane protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 53330 Tuberculist Genomic Region
56043 aldo-keto reductase family 1, member E1 Details for - - aldo-keto reductase family 1, member E1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56043 Tuberculist Genomic Region	56454 aldehyde dehydrogenase 18 family, member A1 Details for - - aldehyde dehydrogenase 18 family, member A1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56454 Tuberculist Genomic Region
64099 parvin, gamma Details for RP23-23A6.2 - parvin, gamma GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 64099 Tuberculist Genomic Region	66073 thioredoxin domain containing 12 (endoplasmic reticulum) Details for RP23-31C9.2 - thioredoxin domain containing 12 (endoplasmic reticulum) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66073 Tuberculist Genomic Region
67623 transmembrane 7 superfamily member 3 Details for RP23-158O11.3 - transmembrane 7 superfamily member 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67623 Tuberculist Genomic Region	67710 polymerase (RNA) II (DNA directed) polypeptide G Details for - - polymerase (RNA) II (DNA directed) polypeptide G GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67710 Tuberculist Genomic Region
67826 synaptosomal-associated protein, 47 Details for RP23-378H5.4 - synaptosomal-associated protein, 47 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67826 Tuberculist Genomic Region	68038 chitinase domain containing 1 Details for - - chitinase domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68038 Tuberculist Genomic Region
68055 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit S Details for - - ATP synthase, H+ transporting, mitochondrial F0 complex, subunit S GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68055 Tuberculist Genomic Region	68472 transmembrane protein 126B Details for - - transmembrane protein 126B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68472 Tuberculist Genomic Region
69226 sorting nexing 24 Details for - - sorting nexing 24 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69226 Tuberculist Genomic Region	69478 RIKEN cDNA 2300009A05 gene Details for - - RIKEN cDNA 2300009A05 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69478 Tuberculist Genomic Region
69807 tripartite motif-containing 32 Details for RP23-468K2.1 - tripartite motif-containing 32 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69807 Tuberculist Genomic Region	72039 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) Details for - - methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72039 Tuberculist Genomic Region
74616 secernin 3 Details for RP23-463K8.3 - secernin 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74616 Tuberculist Genomic Region	74653 protein-O-mannose kinase Details for - - protein-O-mannose kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74653 Tuberculist Genomic Region
20226 seryl-aminoacyl-tRNA synthetase Details for RP23-37G19.1 - seryl-aminoacyl-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20226 Tuberculist Genomic Region	217473 ankyrin repeat and MYND domain containing 2 Details for - - ankyrin repeat and MYND domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217473 Tuberculist Genomic Region
52626 CDKN2A interacting protein N-terminal like Details for RP23-263C23.1 - CDKN2A interacting protein N-terminal like GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 52626 Tuberculist Genomic Region	84505 SET domain, bifurcated 1 Details for - - SET domain, bifurcated 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 84505 Tuberculist Genomic Region
224014 FYVE, RhoGEF and PH domain containing 4 Details for - - FYVE, RhoGEF and PH domain containing 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 224014 Tuberculist Genomic Region	231670 F-box protein 21 Details for - - F-box protein 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231670 Tuberculist Genomic Region
76608 HECT domain containing 3 Details for RP23-419D6.4 - HECT domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76608 Tuberculist Genomic Region	14247 Friend leukemia integration 1 Details for - - Friend leukemia integration 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14247 Tuberculist Genomic Region
74551 phosphoenolpyruvate carboxykinase 2 (mitochondrial) Details for - - phosphoenolpyruvate carboxykinase 2 (mitochondrial) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74551 Tuberculist Genomic Region

Summary

Members

Details for - - protection of telomeres 1A

Details for - - GINS complex subunit 4 (Sld5 homolog)

Details for - - RIKEN cDNA C330006A16 gene

Details for RP23-241M12.1 - brain glycogen phosphorylase

Details for - - eukaryotic translation initiation factor 2D

Details for RP23-374N19.2 - MAP kinase-interacting serine/threonine kinase 1

Details for - - sphingomyelin phosphodiesterase 2, neutral

Details for - - WD repeat domain 11

Details for - - lectin, mannose-binding 2-like

Details for - - leucine rich repeat containing 20

Details for - - membrane magnesium transporter 2

Details for - - ring finger protein 144B

Details for - - ADP-ribosylation factor-like 11

Details for - - zinc finger protein 60

Details for - - protein inhibitor of activated STAT 3

Details for - - GUF1 GTPase homolog (S. cerevisiae)

Details for - - TBC1 domain family, member 17

Details for - - zinc finger protein 760

Details for - - F-box and WD-40 domain protein 4

Details for - - ER membrane associated RNA degradation

Details for - - F-box protein 8

Details for - - vesicle-associated membrane protein 4

Details for - - aldo-keto reductase family 1, member E1

Details for - - aldehyde dehydrogenase 18 family, member A1

Details for RP23-23A6.2 - parvin, gamma

Details for RP23-31C9.2 - thioredoxin domain containing 12 (endoplasmic reticulum)

Details for RP23-158O11.3 - transmembrane 7 superfamily member 3

Details for - - polymerase (RNA) II (DNA directed) polypeptide G

Details for RP23-378H5.4 - synaptosomal-associated protein, 47

Details for - - chitinase domain containing 1

Details for - - ATP synthase, H+ transporting, mitochondrial F0 complex, subunit S

Details for - - transmembrane protein 126B

Details for - - sorting nexing 24

Details for - - RIKEN cDNA 2300009A05 gene

Details for RP23-468K2.1 - tripartite motif-containing 32

Details for - - methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)

Details for RP23-463K8.3 - secernin 3

Details for - - protein-O-mannose kinase

Details for RP23-37G19.1 - seryl-aminoacyl-tRNA synthetase

Details for - - ankyrin repeat and MYND domain containing 2

Details for RP23-263C23.1 - CDKN2A interacting protein N-terminal like

Details for - - SET domain, bifurcated 1

Details for - - FYVE, RhoGEF and PH domain containing 4

Details for - - F-box protein 21

Details for RP23-419D6.4 - HECT domain containing 3

Details for - - Friend leukemia integration 1

Details for - - phosphoenolpyruvate carboxykinase 2 (mitochondrial)

GO Terms

3p UTR PITA