PITA_201 megaCluster: 7 Residual: 0.20 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_201	7	0.20	15	0	0.931584	0

Members

Displaying 1 - 37 of 37

77032 thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 Details for - - thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77032 Tuberculist Genomic Region	79464 lipoic acid synthetase Details for - - lipoic acid synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 79464 Tuberculist Genomic Region
100163 platelet-activating factor acetylhydrolase 2 Details for - - platelet-activating factor acetylhydrolase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100163 Tuberculist Genomic Region	100502698 RIKEN cDNA 1700021K19 gene Details for mCG_130134 - RIKEN cDNA 1700021K19 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100502698 Tuberculist Genomic Region
108645 methionine adenosyltransferase II, beta Details for RP23-382C18.2 - methionine adenosyltransferase II, beta GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108645 Tuberculist Genomic Region	108689 oligonucleotide/oligosaccharide-binding fold containing 1 Details for - - oligonucleotide/oligosaccharide-binding fold containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108689 Tuberculist Genomic Region
170749 myotubularin related protein 4 Details for RP23-168C20.3 - myotubularin related protein 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 170749 Tuberculist Genomic Region	17939 N-acetyl galactosaminidase, alpha Details for - - N-acetyl galactosaminidase, alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17939 Tuberculist Genomic Region
18041 nitrogen fixation gene 1 (S. cerevisiae) Details for RP23-220D12.8 - nitrogen fixation gene 1 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18041 Tuberculist Genomic Region	18642 phosphofructokinase, muscle Details for - - phosphofructokinase, muscle GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18642 Tuberculist Genomic Region
19340 RAB3D, member RAS oncogene family Details for - - RAB3D, member RAS oncogene family GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19340 Tuberculist Genomic Region	20585 helicase-like transcription factor Details for - - helicase-like transcription factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20585 Tuberculist Genomic Region
216440 amplified in osteosarcoma Details for - - amplified in osteosarcoma GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 216440 Tuberculist Genomic Region	217737 AHA1, activator of heat shock protein ATPase 1 Details for - - AHA1, activator of heat shock protein ATPase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217737 Tuberculist Genomic Region
22273 ubiquinol-cytochrome c reductase core protein 1 Details for - - ubiquinol-cytochrome c reductase core protein 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22273 Tuberculist Genomic Region	22591 xeroderma pigmentosum, complementation group C Details for - - xeroderma pigmentosum, complementation group C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22591 Tuberculist Genomic Region
22594 X-ray repair complementing defective repair in Chinese hamster cells 1 Details for - - X-ray repair complementing defective repair in Chinese hamster cells 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22594 Tuberculist Genomic Region	231803 methylphosphate capping enzyme Details for - - methylphosphate capping enzyme GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 231803 Tuberculist Genomic Region
232536 mitochondrial ribosomal protein S35 Details for RP23-157O3.2 - mitochondrial ribosomal protein S35 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 232536 Tuberculist Genomic Region	234814 methenyltetrahydrofolate synthetase domain containing Details for - - methenyltetrahydrofolate synthetase domain containing GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234814 Tuberculist Genomic Region
23908 heparan sulfate 2-O-sulfotransferase 1 Details for - - heparan sulfate 2-O-sulfotransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23908 Tuberculist Genomic Region	23992 protein kinase, interferon inducible double stranded RNA dependent activator Details for RP23-468L22.1 - protein kinase, interferon inducible double stranded RNA dependent activator GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 23992 Tuberculist Genomic Region
245867 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 Details for RP23-322G1.5 - protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 245867 Tuberculist Genomic Region	27267 cysteinyl-tRNA synthetase Details for - - cysteinyl-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 27267 Tuberculist Genomic Region
56401 leprecan 1 Details for RP23-344D2.11-004 - leprecan 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56401 Tuberculist Genomic Region	67397 endoplasmic reticulum protein 29 Details for - - endoplasmic reticulum protein 29 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67397 Tuberculist Genomic Region
67939 prolyl-tRNA synthetase domain containing 1 Details for RP23-92B18.3 - prolyl-tRNA synthetase domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67939 Tuberculist Genomic Region	68767 WAS protein family homolog Details for - - WAS protein family homolog GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68767 Tuberculist Genomic Region
68927 pentatricopeptide repeat domain 2 Details for - - pentatricopeptide repeat domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68927 Tuberculist Genomic Region	70209 transmembrane protein 143 Details for - - transmembrane protein 143 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70209 Tuberculist Genomic Region
71918 zinc finger, CCHC domain containing 24 Details for - - zinc finger, CCHC domain containing 24 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71918 Tuberculist Genomic Region	73825 protein phosphatase 1, regulatory subunit 21 Details for - - protein phosphatase 1, regulatory subunit 21 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73825 Tuberculist Genomic Region
74764 kinesin light chain 4 Details for - - kinesin light chain 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74764 Tuberculist Genomic Region	93747 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial Details for - - enoyl Coenzyme A hydratase, short chain, 1, mitochondrial GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 93747 Tuberculist Genomic Region
227099 postmeiotic segregation increased 1 (S. cerevisiae) Details for - - postmeiotic segregation increased 1 (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 227099 Tuberculist Genomic Region	66948 acyl-Coenzyme A dehydrogenase family, member 8 Details for - - acyl-Coenzyme A dehydrogenase family, member 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66948 Tuberculist Genomic Region
75415 Rho GTPase activating protein 12 Details for - - Rho GTPase activating protein 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 75415 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
GABPA_ETS_full_monomeric_10_1	0.405405	0.00000184

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000054	ATTTTYTTTTYT	NA	0.000012	RGGGGCGGGGC	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$SP1_Q6_M00196, V$SP4_Q5_M01273, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$SP1_Q4_01_M00932, V$GC_01_M00255, V$SP1_02_M01303, V$KLF7_03_M02773, V$UF1H3BETA_Q6_M01068, V$SP2_01_M01783, V$ZFP281_01_M01597, V$GKLF_02_M01588, V$MAZR_01_M00491, V$CKROX_Q2_M01175, V$SP1_03_M02281, V$MAZ_Q6_M00649, V$SP4_03_M02810, V$SP1_01_M00008, V$E2F3_Q6_M02089, V$SMAD4_04_M02898, V$ETF_Q6_M00695, V$MAZ_Q6_01_M02023, V$BCL6B_04_M02844, V$ZFP281_04_M02831, V$ZBP89_Q4_M01816, V$EGR1_Q6_M01873, V$CACD_01_M01113, V$ZNF219_01_M01122, V$KROX_Q6_M00982, V$EGR1_06_M02744, V$KLF15_Q2_M01714, V$SP1SP3_Q4_M01219, V$ZFP410_04_M02936, V$SP4_04_M02914, V$CACBINDINGPROTEIN_Q6_M00720, V$ZFP740_03_M02834, V$FKLF_Q5_M01837, Klf7.1, Sp4.1, Smad3.1, Zfp281.2, Bcl6b.2, Egr1.1, Zfp410.1, Zfp740.1, Sp4.2, KLF16_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, KLF13_C2H2_full_monomeric_18_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.32	CGACGT	Gmeb1.1	1.24	CAAGCGGC	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.46	AGGCTC	NA	NA	0.7	TTGCNNCT	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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