PITA_51 megaCluster: 10 Residual: 0.19

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
PITA_51	10	0.19	15	0	0.939928	0

Members

Displaying 1 - 41 of 41

TFBS DB TF

TFs	percTargets	pValue
V_FOXO4_01_M00472	0.25	0.000000446

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000071	AAAAAAANAAA	NA	0.006	RGCCCCGCCCCN	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$SP1_Q4_01_M00932, V$SP4_Q5_M01273, V$GC_01_M00255, V$SP1_Q2_01_M00933, V$KLF7_03_M02773, V$SP1_02_M01303, V$GKLF_02_M01588, V$CKROX_Q2_M01175, V$SP4_03_M02810, V$MAZR_01_M00491, V$SP1_03_M02281, V$BCL6B_04_M02844, V$SP1_01_M00008, V$MAZ_Q6_M00649, V$SMAD4_04_M02898, V$ZFP281_01_M01597, V$SP2_01_M01783, V$UF1H3BETA_Q6_M01068, V$E2F3_Q6_M02089, V$EGR1_Q6_M01873, V$ZFP410_04_M02936, V$SP4_04_M02914, V$CACD_01_M01113, V$KLF15_Q2_M01714, V$ETF_Q6_M00695, V$ZBP89_Q4_M01816, V$ZFP281_04_M02831, V$KROX_Q6_M00982, V$EGR1_06_M02744, V$ZFP740_03_M02834, V$MAZ_Q6_01_M02023, V$ZNF219_01_M01122, V$WT1_Q6_01_M02036, V$SP1SP3_Q4_M01219, V$EKLF_Q5_M01874, V$EGR_Q6_M00807, V$FKLF_Q5_M01837, V$ASCL2_04_M02841, V$E2F_Q2_M00803, Klf7.1, Sp4.1, Bcl6b.2, Smad3.1, Zfp410.1, Sp4.2, Egr1.1, Zfp281.2, Zfp740.1, Ascl2.2, Zif268.1, Sox13.2, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, KLF14_C2H2_DBD_monomeric_14_1, SP3_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1, ZNF740_C2H2_full_monomeric_10_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.3	ACGGCG	NA	1.37	GCGAACGG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.4	CGAACG	NA	NA	0.58	ANGAANGC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-154	0.666667	0.00000636

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-421	0.461538	0.00000451

105148 isoleucine-tRNA synthetase Details for - - isoleucine-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 105148 Tuberculist Genomic Region	105727 solute carrier family 38, member 1 Details for - - solute carrier family 38, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 105727 Tuberculist Genomic Region
107271 tyrosyl-tRNA synthetase Details for - - tyrosyl-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 107271 Tuberculist Genomic Region	108012 adaptor-related protein complex 1, sigma 2 subunit Details for RP23-391L6.1 - adaptor-related protein complex 1, sigma 2 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108012 Tuberculist Genomic Region
110750 chromosome segregation 1-like (S. cerevisiae) Details for RP23-19L12.9 - chromosome segregation 1-like (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 110750 Tuberculist Genomic Region	11772 adaptor-related protein complex 2, alpha 2 subunit Details for - - adaptor-related protein complex 2, alpha 2 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11772 Tuberculist Genomic Region
12567 cyclin-dependent kinase 4 Details for - - cyclin-dependent kinase 4 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12567 Tuberculist Genomic Region	13860 epidermal growth factor receptor pathway substrate 8 Details for - - epidermal growth factor receptor pathway substrate 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13860 Tuberculist Genomic Region
14218 SH3 and PX domains 2A Details for - - SH3 and PX domains 2A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14218 Tuberculist Genomic Region	14420 galactosylceramidase Details for - - galactosylceramidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14420 Tuberculist Genomic Region
14456 growth arrest specific 6 Details for - - growth arrest specific 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14456 Tuberculist Genomic Region	15107 hydroxyacyl-Coenzyme A dehydrogenase Details for - - hydroxyacyl-Coenzyme A dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15107 Tuberculist Genomic Region
15929 isocitrate dehydrogenase 3 (NAD+), gamma Details for RP23-373N8.5 - isocitrate dehydrogenase 3 (NAD+), gamma GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15929 Tuberculist Genomic Region	16653 v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog Details for RP24-359O2.1 - v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16653 Tuberculist Genomic Region
20440 beta galactoside alpha 2,6 sialyltransferase 1 Details for - - beta galactoside alpha 2,6 sialyltransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20440 Tuberculist Genomic Region	22275 uroporphyrinogen decarboxylase Details for RP23-419D6.3 - uroporphyrinogen decarboxylase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22275 Tuberculist Genomic Region
226414 aspartyl-tRNA synthetase Details for - - aspartyl-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226414 Tuberculist Genomic Region	235132 zinc finger and BTB domain containing 44 Details for - - zinc finger and BTB domain containing 44 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 235132 Tuberculist Genomic Region
236792 membrane magnesium transporter 1 Details for - - membrane magnesium transporter 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236792 Tuberculist Genomic Region	238505 5-methyltetrahydrofolate-homocysteine methyltransferase Details for - - 5-methyltetrahydrofolate-homocysteine methyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 238505 Tuberculist Genomic Region
242474 transmembrane protein 245 Details for RP23-455B1.3 - transmembrane protein 245 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 242474 Tuberculist Genomic Region	252972 two pore channel 1 Details for - - two pore channel 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 252972 Tuberculist Genomic Region
28042 ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) Details for - - ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 28042 Tuberculist Genomic Region	56752 aldehyde dehydrogenase 9, subfamily A1 Details for - - aldehyde dehydrogenase 9, subfamily A1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56752 Tuberculist Genomic Region
57750 WD repeat domain 12 Details for MNCb-5414 - WD repeat domain 12 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 57750 Tuberculist Genomic Region	59044 ring finger protein 130 Details for RP23-319B15.1 - ring finger protein 130 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 59044 Tuberculist Genomic Region
65964 sterile alpha motif and leucine zipper containing kinase AZK Details for RP23-146F24.1 - sterile alpha motif and leucine zipper containing kinase AZK GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65964 Tuberculist Genomic Region	66129 AhpC/TSA antioxidant enzyme domain containing 1 Details for - - AhpC/TSA antioxidant enzyme domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66129 Tuberculist Genomic Region
67054 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase Details for - - phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67054 Tuberculist Genomic Region	68161 RIKEN cDNA A930005H10 gene Details for - - RIKEN cDNA A930005H10 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68161 Tuberculist Genomic Region
69930 zinc finger protein 715 Details for - - zinc finger protein 715 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69930 Tuberculist Genomic Region	70088 MYST/Esa1-associated factor 6 Details for RP23-325M14.8 - MYST/Esa1-associated factor 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70088 Tuberculist Genomic Region
73910 Rho GTPase activating protein 18 Details for - - Rho GTPase activating protein 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73910 Tuberculist Genomic Region	76117 Rho GTPase activating protein 15 Details for RP23-211K16.1 - Rho GTPase activating protein 15 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76117 Tuberculist Genomic Region
76267 fatty acid desaturase 1 Details for - - fatty acid desaturase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76267 Tuberculist Genomic Region	83429 cystinosis, nephropathic Details for RP23-263M10.9 - cystinosis, nephropathic GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 83429 Tuberculist Genomic Region
97998 DEP domain containing MTOR-interacting protein Details for - - DEP domain containing MTOR-interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 97998 Tuberculist Genomic Region	17064 CD93 antigen Details for RP23-70N3.4 - CD93 antigen GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17064 Tuberculist Genomic Region
234353 pleckstrin and Sec7 domain containing 3 Details for - - pleckstrin and Sec7 domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 234353 Tuberculist Genomic Region	69726 SET and MYND domain containing 3 Details for - - SET and MYND domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69726 Tuberculist Genomic Region
54486 hematopoietic prostaglandin D synthase Details for - - hematopoietic prostaglandin D synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54486 Tuberculist Genomic Region

Summary

Members

Details for - - isoleucine-tRNA synthetase

Details for - - solute carrier family 38, member 1

Details for - - tyrosyl-tRNA synthetase

Details for RP23-391L6.1 - adaptor-related protein complex 1, sigma 2 subunit

Details for RP23-19L12.9 - chromosome segregation 1-like (S. cerevisiae)

Details for - - adaptor-related protein complex 2, alpha 2 subunit

Details for - - cyclin-dependent kinase 4

Details for - - epidermal growth factor receptor pathway substrate 8

Details for - - SH3 and PX domains 2A

Details for - - galactosylceramidase

Details for - - growth arrest specific 6

Details for - - hydroxyacyl-Coenzyme A dehydrogenase

Details for RP23-373N8.5 - isocitrate dehydrogenase 3 (NAD+), gamma

Details for RP24-359O2.1 - v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Details for - - beta galactoside alpha 2,6 sialyltransferase 1

Details for RP23-419D6.3 - uroporphyrinogen decarboxylase

Details for - - aspartyl-tRNA synthetase

Details for - - zinc finger and BTB domain containing 44

Details for - - membrane magnesium transporter 1

Details for - - 5-methyltetrahydrofolate-homocysteine methyltransferase

Details for RP23-455B1.3 - transmembrane protein 245

Details for - - two pore channel 1

Details for - - ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)

Details for - - aldehyde dehydrogenase 9, subfamily A1

Details for MNCb-5414 - WD repeat domain 12

Details for RP23-319B15.1 - ring finger protein 130

Details for RP23-146F24.1 - sterile alpha motif and leucine zipper containing kinase AZK

Details for - - AhpC/TSA antioxidant enzyme domain containing 1

Details for - - phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase

Details for - - RIKEN cDNA A930005H10 gene

Details for - - zinc finger protein 715

Details for RP23-325M14.8 - MYST/Esa1-associated factor 6

Details for - - Rho GTPase activating protein 18

Details for RP23-211K16.1 - Rho GTPase activating protein 15

Details for - - fatty acid desaturase 1

Details for RP23-263M10.9 - cystinosis, nephropathic

Details for - - DEP domain containing MTOR-interacting protein

Details for RP23-70N3.4 - CD93 antigen

Details for - - pleckstrin and Sec7 domain containing 3

Details for - - SET and MYND domain containing 3

Details for - - hematopoietic prostaglandin D synthase

GO Terms

3p UTR PITA