TargetScan_157 megaCluster: 10 Residual: 0.26 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_157	10	0.26	15	0	0.880125	0

Members

Displaying 1 - 34 of 34

105727 solute carrier family 38, member 1 Details for - - solute carrier family 38, member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 105727 Tuberculist Genomic Region	106581 integrin alpha FG-GAP repeat containing 3 Details for - - integrin alpha FG-GAP repeat containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 106581 Tuberculist Genomic Region
108099 protein kinase, AMP-activated, gamma 2 non-catalytic subunit Details for - - protein kinase, AMP-activated, gamma 2 non-catalytic subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108099 Tuberculist Genomic Region	12908 carnitine acetyltransferase Details for RP23-395P6.8 - carnitine acetyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12908 Tuberculist Genomic Region
225115 supervillin Details for - - supervillin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 225115 Tuberculist Genomic Region	228482 Rho GTPase activating protein 11A Details for RP23-288M21.5 - Rho GTPase activating protein 11A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 228482 Tuberculist Genomic Region
236794 solute carrier family 9 (sodium/hydrogen exchanger), member 6 Details for RP23-105E2.4 - solute carrier family 9 (sodium/hydrogen exchanger), member 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 236794 Tuberculist Genomic Region	24017 ring finger protein 13 Details for - - ring finger protein 13 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 24017 Tuberculist Genomic Region
252972 two pore channel 1 Details for - - two pore channel 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 252972 Tuberculist Genomic Region	28042 ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) Details for - - ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 28042 Tuberculist Genomic Region
65964 sterile alpha motif and leucine zipper containing kinase AZK Details for RP23-146F24.1 - sterile alpha motif and leucine zipper containing kinase AZK GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65964 Tuberculist Genomic Region	66310 dpy-30 homolog (C. elegans) Details for - - dpy-30 homolog (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66310 Tuberculist Genomic Region
69048 solute carrier family 30 (zinc transporter), member 5 Details for - - solute carrier family 30 (zinc transporter), member 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69048 Tuberculist Genomic Region	76117 Rho GTPase activating protein 15 Details for RP23-211K16.1 - Rho GTPase activating protein 15 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76117 Tuberculist Genomic Region
97998 DEP domain containing MTOR-interacting protein Details for - - DEP domain containing MTOR-interacting protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 97998 Tuberculist Genomic Region	114863 proline synthetase co-transcribed Details for - - proline synthetase co-transcribed GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 114863 Tuberculist Genomic Region
11534 adenosine kinase Details for - - adenosine kinase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11534 Tuberculist Genomic Region	11690 arachidonate 5-lipoxygenase activating protein Details for - - arachidonate 5-lipoxygenase activating protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11690 Tuberculist Genomic Region
11772 adaptor-related protein complex 2, alpha 2 subunit Details for - - adaptor-related protein complex 2, alpha 2 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11772 Tuberculist Genomic Region	12235 budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) Details for RP23-189N15.7 - budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12235 Tuberculist Genomic Region
12428 cyclin A2 Details for - - cyclin A2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12428 Tuberculist Genomic Region	12499 ectonucleoside triphosphate diphosphohydrolase 5 Details for - - ectonucleoside triphosphate diphosphohydrolase 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12499 Tuberculist Genomic Region
12534 cyclin-dependent kinase 1 Details for - - cyclin-dependent kinase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12534 Tuberculist Genomic Region	13605 ect2 oncogene Details for - - ect2 oncogene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13605 Tuberculist Genomic Region
15929 isocitrate dehydrogenase 3 (NAD+), gamma Details for RP23-373N8.5 - isocitrate dehydrogenase 3 (NAD+), gamma GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15929 Tuberculist Genomic Region	19128 protein S (alpha) Details for - - protein S (alpha) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19128 Tuberculist Genomic Region
194590 RALBP1 associated Eps domain containing protein 2 Details for RP23-436I3.2 - RALBP1 associated Eps domain containing protein 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 194590 Tuberculist Genomic Region	381680 neurexophilin and PC-esterase domain family, member 5 Details for - - neurexophilin and PC-esterase domain family, member 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 381680 Tuberculist Genomic Region
56224 tetraspanin 5 Details for - - tetraspanin 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 56224 Tuberculist Genomic Region	67475 ERO1-like beta (S. cerevisiae) Details for - - ERO1-like beta (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67475 Tuberculist Genomic Region
72722 family with sequence similarity 98, member A Details for - - family with sequence similarity 98, member A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72722 Tuberculist Genomic Region	72787 NDC1 transmembrane nucleoporin Details for RP23-392J14.4 - NDC1 transmembrane nucleoporin GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72787 Tuberculist Genomic Region
73086 ribosomal protein S6 kinase, polypeptide 5 Details for - - ribosomal protein S6 kinase, polypeptide 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 73086 Tuberculist Genomic Region	98711 retinol dehydrogenase 10 (all-trans) Details for - - retinol dehydrogenase 10 (all-trans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 98711 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
Zfp281.2, V_SP1_02_M01303, V_ZFP281_04_M02831	1, 1, 1	0

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.000000014	AAAAAARAAAA	NA	0.051	GGGGGCGGGGC	Klf4_MA0039.2, SP1_MA0079.2, SP1_MA0079.1, V$SP4_Q5_M01273, V$SP1_Q6_M00196, V$SP1_Q6_01_M00931, V$SP1_Q2_01_M00933, V$SP1_Q4_01_M00932, V$KLF7_03_M02773, V$GC_01_M00255, V$GKLF_02_M01588, V$SP4_03_M02810, V$UF1H3BETA_Q6_M01068, V$SP1_02_M01303, V$SP1_03_M02281, V$ZFP281_01_M01597, V$SP2_01_M01783, V$MAZR_01_M00491, V$SP1_01_M00008, V$CKROX_Q2_M01175, V$E2F3_Q6_M02089, V$MAZ_Q6_M00649, V$EGR1_Q6_M01873, V$SMAD4_04_M02898, V$KROX_Q6_M00982, V$CACD_01_M01113, V$EGR1_06_M02744, V$ZFP281_04_M02831, V$ZNF219_01_M01122, V$ZBP89_Q4_M01816, V$SP1SP3_Q4_M01219, V$MAZ_Q6_01_M02023, V$WT1_Q6_01_M02036, V$ZFP740_03_M02834, V$BCL6B_04_M02844, V$EKLF_Q5_M01874, V$SP4_04_M02914, V$KLF15_Q2_M01714, V$ETF_Q6_M00695, V$CACBINDINGPROTEIN_Q6_M00720, V$ZFP410_04_M02936, V$E2F_Q2_M00803, V$EGR_Q6_M00807, Klf7.1, Sp4.1, Egr1.1, Smad3.1, Zfp281.2, Zfp740.1, Bcl6b.2, Sp4.2, Zfp410.1, Zif268.1, SP4_C2H2_full_monomeric_17_1, KLF16_C2H2_DBD_monomeric_11_1, KLF14_C2H2_DBD_monomeric_14_1, SP1_C2H2_DBD_monomeric_11_1, SP3_C2H2_DBD_monomeric_11_1, KLF13_C2H2_full_monomeric_18_1, SP8_C2H2_DBD_monomeric_12_1, Klf12_C2H2_DBD_monomeric_15_1, ZNF740_C2H2_full_monomeric_10_1, Egr1_C2H2_mouse-DBD_mutant_DBD_monomeric_16_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.26	NCGCGGCG	NA		NA	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.57	GANGCT	NA	NA	0.67	ANGTACAC	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-337-5p	0.344828	0.0000059

3p UTR TargetScan

miRNAs	percTargets	pValue
NA

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