TargetScan_161 megaCluster: 3 Residual: 0.20 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_161	3	0.20	15	0	0.920991	0

Members

Displaying 1 - 36 of 36

100504117 cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), opposite strand Details for - - cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), opposite strand GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 100504117 Tuberculist Genomic Region	108960 interleukin-1 receptor-associated kinase 2 Details for - - interleukin-1 receptor-associated kinase 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108960 Tuberculist Genomic Region
109934 active BCR-related gene Details for RP23-48B14.2 - active BCR-related gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 109934 Tuberculist Genomic Region	12914 CREB binding protein Details for - - CREB binding protein GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12914 Tuberculist Genomic Region
17342 microphthalmia-associated transcription factor Details for - - microphthalmia-associated transcription factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 17342 Tuberculist Genomic Region	20525 solute carrier family 2 (facilitated glucose transporter), member 1 Details for RP23-344D2.2 - solute carrier family 2 (facilitated glucose transporter), member 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20525 Tuberculist Genomic Region
21859 tissue inhibitor of metalloproteinase 3 Details for - - tissue inhibitor of metalloproteinase 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 21859 Tuberculist Genomic Region	226562 proline-rich coiled-coil 2C Details for - - proline-rich coiled-coil 2C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226562 Tuberculist Genomic Region
26374 ring finger and WD repeat domain 2 Details for mCG_124354 - ring finger and WD repeat domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26374 Tuberculist Genomic Region	26896 mediator complex subunit 14 Details for RP24-392J24.6 - mediator complex subunit 14 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26896 Tuberculist Genomic Region
328365 zinc finger, MIZ-type containing 1 Details for - - zinc finger, MIZ-type containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 328365 Tuberculist Genomic Region	338365 solute carrier family 41, member 2 Details for - - solute carrier family 41, member 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 338365 Tuberculist Genomic Region
67434 ankyrin repeat domain 33B Details for - - ankyrin repeat domain 33B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67434 Tuberculist Genomic Region	68142 INO80 homolog (S. cerevisiae) Details for RP23-46P4.10-001 - INO80 homolog (S. cerevisiae) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68142 Tuberculist Genomic Region
68473 MOB kinase activator 1B Details for - - MOB kinase activator 1B GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68473 Tuberculist Genomic Region	72472 solute carrier family 16 (monocarboxylic acid transporters), member 10 Details for - - solute carrier family 16 (monocarboxylic acid transporters), member 10 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 72472 Tuberculist Genomic Region
74155 ERBB receptor feedback inhibitor 1 Details for RP23-272N19.4 - ERBB receptor feedback inhibitor 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74155 Tuberculist Genomic Region	77036 RIKEN cDNA 1700109H08 gene Details for - - RIKEN cDNA 1700109H08 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 77036 Tuberculist Genomic Region
791405 predicted gene 10002 Details for - - predicted gene 10002 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 791405 Tuberculist Genomic Region	83925 trichorhinophalangeal syndrome I (human) Details for - - trichorhinophalangeal syndrome I (human) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 83925 Tuberculist Genomic Region
104215 ras homolog gene family, member Q Details for - - ras homolog gene family, member Q GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 104215 Tuberculist Genomic Region	12363 caspase 4, apoptosis-related cysteine peptidase Details for - - caspase 4, apoptosis-related cysteine peptidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12363 Tuberculist Genomic Region
12393 runt related transcription factor 2 Details for - - runt related transcription factor 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12393 Tuberculist Genomic Region	14260 formin 1 Details for RP23-248J10.1 - formin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14260 Tuberculist Genomic Region
15937 immediate early response 3 Details for - - immediate early response 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15937 Tuberculist Genomic Region	18590 platelet derived growth factor, alpha Details for - - platelet derived growth factor, alpha GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 18590 Tuberculist Genomic Region
258565 olfactory receptor 1009 Details for RP23-16D18.13-001 - olfactory receptor 1009 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 258565 Tuberculist Genomic Region	30940 ubiquitin specific peptidase 25 Details for - - ubiquitin specific peptidase 25 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 30940 Tuberculist Genomic Region
320207 phosphoinositide-3-kinase, regulatory subunit 5, p101 Details for RP23-432M23.2 - phosphoinositide-3-kinase, regulatory subunit 5, p101 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 320207 Tuberculist Genomic Region	503610 zinc finger, DHHC domain containing 18 Details for RP23-137L22.12-001 - zinc finger, DHHC domain containing 18 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 503610 Tuberculist Genomic Region
71436 fibronectin leucine rich transmembrane protein 3 Details for RP23-388J20.1 - fibronectin leucine rich transmembrane protein 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 71436 Tuberculist Genomic Region	74277 cysteine-rich hydrophobic domain 2 Details for - - cysteine-rich hydrophobic domain 2 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 74277 Tuberculist Genomic Region
19271 protein tyrosine phosphatase, receptor type, J Details for RP24-113P16.2 - protein tyrosine phosphatase, receptor type, J GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 19271 Tuberculist Genomic Region	16798 large tumor suppressor Details for - - large tumor suppressor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16798 Tuberculist Genomic Region
54004 diaphanous homolog 2 (Drosophila) Details for - - diaphanous homolog 2 (Drosophila) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54004 Tuberculist Genomic Region	67712 solute carrier family 25, member 37 Details for - - solute carrier family 25, member 37 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 67712 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_SRF_Q5_01_M00922	0.235294	0.0000289

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000000003	TAAAAAAAAAAA	NA	0.14	CCCTCCCCCNCC	SP1_MA0079.2, V$UF1H3BETA_Q6_M01068, V$MAZ_Q6_M00649, V$ZFP281_01_M01597, V$CKROX_Q2_M01175, V$ZFP281_04_M02831, V$SP1_03_M02281, V$ZBP89_Q4_M01816, V$KROX_Q6_M00982, V$SP1SP3_Q4_M01219, V$SP4_Q5_M01273, V$EGR1_Q6_M01873, V$CACBINDINGPROTEIN_Q6_M00720, V$MAZR_01_M00491, V$SP1_Q2_01_M00933, V$ZNF219_01_M01122, V$WT1_Q6_01_M02036, V$TFIII_Q6_M00706, V$SP1_Q6_M00196, V$SP1_02_M01303, V$MAZ_Q6_01_M02023, V$SP1_Q4_01_M00932, V$WT1_Q6_M01118, V$EGR1_06_M02744, V$SP4_03_M02810, V$SP1_Q6_01_M00931, V$ETF_Q6_M00695, V$FPM315_01_M01587, V$FKLF_Q5_M01837, V$BCL6B_04_M02844, V$MOVOB_01_M01104, V$GC_01_M00255, V$GKLF_Q4_M01835, Zfp281.2, Egr1.1, Sp4.1, Bcl6b.2, Zfp740.1, Klf7.1, Zfp410.1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.3	CGAGCG	NA	1.33	NCGCTCCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.46	TAANGG	NA	NA	0.54	ANNTAGTG	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
mmu-miR-214, mmu-miR-761	0.928571	0.0000000645

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-466l-3p	0.833333	0.0000000000856

Add comment

Log in or register to post comments