TargetScan_188 megaCluster: 10 Residual: 0.18 | Macrophage Network Portal

Summary

Title	Cluster	Residual	Bicluster Conditions	Residual Permutation P-Value	Var. Exp. First PC	Var. Exp. First PC Perm. P-Value
TargetScan_188	10	0.18	15	0	0.947173	0

Members

Displaying 1 - 38 of 38

12846 catechol-O-methyltransferase Details for - - catechol-O-methyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12846 Tuberculist Genomic Region	76429 phospholysine phosphohistidine inorganic pyrophosphate phosphatase Details for - - phospholysine phosphohistidine inorganic pyrophosphate phosphatase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76429 Tuberculist Genomic Region
108012 adaptor-related protein complex 1, sigma 2 subunit Details for RP23-391L6.1 - adaptor-related protein complex 1, sigma 2 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 108012 Tuberculist Genomic Region	11727 angiogenin, ribonuclease, RNase A family, 5 Details for - - angiogenin, ribonuclease, RNase A family, 5 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11727 Tuberculist Genomic Region
11992 AU RNA binding protein/enoyl-coenzyme A hydratase Details for - - AU RNA binding protein/enoyl-coenzyme A hydratase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11992 Tuberculist Genomic Region	12908 carnitine acetyltransferase Details for RP23-395P6.8 - carnitine acetyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 12908 Tuberculist Genomic Region
13860 epidermal growth factor receptor pathway substrate 8 Details for - - epidermal growth factor receptor pathway substrate 8 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 13860 Tuberculist Genomic Region	14420 galactosylceramidase Details for - - galactosylceramidase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 14420 Tuberculist Genomic Region
15107 hydroxyacyl-Coenzyme A dehydrogenase Details for - - hydroxyacyl-Coenzyme A dehydrogenase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15107 Tuberculist Genomic Region	15547 TRM2 tRNA methyltransferase 2A Details for - - TRM2 tRNA methyltransferase 2A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 15547 Tuberculist Genomic Region
16337 insulin receptor Details for - - insulin receptor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 16337 Tuberculist Genomic Region	20440 beta galactoside alpha 2,6 sialyltransferase 1 Details for - - beta galactoside alpha 2,6 sialyltransferase 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 20440 Tuberculist Genomic Region
217031 transcriptional adaptor 2A Details for RP23-395B22.4 - transcriptional adaptor 2A GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 217031 Tuberculist Genomic Region	22275 uroporphyrinogen decarboxylase Details for RP23-419D6.3 - uroporphyrinogen decarboxylase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22275 Tuberculist Genomic Region
226414 aspartyl-tRNA synthetase Details for - - aspartyl-tRNA synthetase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 226414 Tuberculist Genomic Region	22644 ring finger protein 103 Details for - - ring finger protein 103 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 22644 Tuberculist Genomic Region
232853 zinc finger protein 954 Details for - - zinc finger protein 954 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 232853 Tuberculist Genomic Region	235132 zinc finger and BTB domain containing 44 Details for - - zinc finger and BTB domain containing 44 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 235132 Tuberculist Genomic Region
238505 5-methyltetrahydrofolate-homocysteine methyltransferase Details for - - 5-methyltetrahydrofolate-homocysteine methyltransferase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 238505 Tuberculist Genomic Region	241066 calcium response factor Details for - - calcium response factor GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 241066 Tuberculist Genomic Region
26926 apoptosis-inducing factor, mitochondrion-associated 1 Details for RP23-35N5.1 - apoptosis-inducing factor, mitochondrion-associated 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 26926 Tuberculist Genomic Region	329416 nitric oxide synthase trafficker Details for RP23-431D4.2 - nitric oxide synthase trafficker GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 329416 Tuberculist Genomic Region
329727 DENN/MADD domain containing 2C Details for - - DENN/MADD domain containing 2C GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 329727 Tuberculist Genomic Region	54486 hematopoietic prostaglandin D synthase Details for - - hematopoietic prostaglandin D synthase GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 54486 Tuberculist Genomic Region
59044 ring finger protein 130 Details for RP23-319B15.1 - ring finger protein 130 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 59044 Tuberculist Genomic Region	60455 transmembrane protein 8 (five membrane-spanning domains) Details for - - transmembrane protein 8 (five membrane-spanning domains) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 60455 Tuberculist Genomic Region
65964 sterile alpha motif and leucine zipper containing kinase AZK Details for RP23-146F24.1 - sterile alpha motif and leucine zipper containing kinase AZK GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 65964 Tuberculist Genomic Region	66129 AhpC/TSA antioxidant enzyme domain containing 1 Details for - - AhpC/TSA antioxidant enzyme domain containing 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66129 Tuberculist Genomic Region
66257 nicolin 1 Details for - - nicolin 1 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66257 Tuberculist Genomic Region	66310 dpy-30 homolog (C. elegans) Details for - - dpy-30 homolog (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 66310 Tuberculist Genomic Region
68161 RIKEN cDNA A930005H10 gene Details for - - RIKEN cDNA A930005H10 gene GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68161 Tuberculist Genomic Region	68318 anterior pharynx defective 1c homolog (C. elegans) Details for - - anterior pharynx defective 1c homolog (C. elegans) GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 68318 Tuberculist Genomic Region
69726 SET and MYND domain containing 3 Details for - - SET and MYND domain containing 3 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 69726 Tuberculist Genomic Region	70088 MYST/Esa1-associated factor 6 Details for RP23-325M14.8 - MYST/Esa1-associated factor 6 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 70088 Tuberculist Genomic Region
76117 Rho GTPase activating protein 15 Details for RP23-211K16.1 - Rho GTPase activating protein 15 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 76117 Tuberculist Genomic Region	83429 cystinosis, nephropathic Details for RP23-263M10.9 - cystinosis, nephropathic GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 83429 Tuberculist Genomic Region
11772 adaptor-related protein complex 2, alpha 2 subunit Details for - - adaptor-related protein complex 2, alpha 2 subunit GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 11772 Tuberculist Genomic Region	242474 transmembrane protein 245 Details for RP23-455B1.3 - transmembrane protein 245 GO Terms: NA PATRIC Pathways: [field_patric_pathways] Essentiality: Griffin Essential: [field_griffin_essential] \| In vitro Essential: [field_in_vitro_essential] \| In vivo Essential: [field_in_vivo_essential] Go to Gene Page: 242474 Tuberculist Genomic Region

TFBS DB TF

TFs	percTargets	pValue
V_FOXO4_01_M00472	0.243243	0.00000179

GO Terms

Displaying 1 - 1 of 1

GO Terms
NA

Upstream MEME Motif

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif2 E-Value	Motif2 Consensus	Motif2 Matches
0.0000000006	AAAKAAAANAAA	NA	3.4	CCCCGCCCCNC	SP1_MA0079.2, Klf4_MA0039.2, V$SP4_Q5_M01273, V$SP1_02_M01303, V$SP1_Q2_01_M00933, V$ZFP281_01_M01597, V$SP1_Q6_M00196, V$SP1_Q4_01_M00932, V$SP1_Q6_01_M00931, V$SP1_03_M02281, V$GKLF_02_M01588, V$UF1H3BETA_Q6_M01068, V$CKROX_Q2_M01175, V$KLF7_03_M02773, V$MAZR_01_M00491, V$GC_01_M00255, V$MAZ_Q6_M00649, V$ZFP281_04_M02831, V$ZBP89_Q4_M01816, V$ZNF219_01_M01122, V$KROX_Q6_M00982, V$ETF_Q6_M00695, V$KLF15_Q2_M01714, V$EKLF_Q5_M01874, V$MAZ_Q6_01_M02023, V$SP1SP3_Q4_M01219, V$BCL6B_04_M02844, V$CACD_01_M01113, V$SP1_01_M00008, V$SP4_03_M02810, V$SP2_01_M01783, V$E2F3_Q6_M02089, V$FKLF_Q5_M01837, V$SMAD4_04_M02898, V$ZFP410_04_M02936, V$EGR1_Q6_M01873, V$ZFP740_03_M02834, V$WT1_Q6_01_M02036, V$CACBINDINGPROTEIN_Q6_M00720, V$CACCCBINDINGFACTOR_Q6_M00721, V$EGR1_06_M02744, Klf7.1, Zfp281.2, Bcl6b.2, Sp4.1, Zfp410.1, Smad3.1, Zfp740.1, Egr1.1, Ascl2.2, SP1_C2H2_DBD_monomeric_11_1, KLF16_C2H2_DBD_monomeric_11_1, ZNF740_C2H2_full_monomeric_10_1, SP3_C2H2_DBD_monomeric_11_1, SP4_C2H2_full_monomeric_17_1, SP8_C2H2_DBD_monomeric_12_1, KLF14_C2H2_DBD_monomeric_14_1, Klf12_C2H2_DBD_monomeric_15_1

Upstream Weeder Motif

Motif1 Score	Motif1 Consensus	Motif1 Matches	Motif2 Score	Motif2 Consensus	Motif2 Matches
1.08	GCGRCG	NA	1.22	CGTGACCG	NA

3p UTR Weeder

Motif1 E-Value	Motif1 Consensus	Motif1 Matches	Motif1 Model	Motif2 E-Value	Motif2 Consensus	Motif2 Matches	Motif2 Model
0.62	TCATCTGT	NA	NA		NA	NA	NA

3p UTR PITA

miRNAs	percTargets	pValue
NA

3p UTR TargetScan

miRNAs	percTargets	pValue
mmu-miR-3074-5p	0.5	0.0000298

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