TargetScan_20 megaCluster: 2 Residual: 0.13

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_20 2 0.13 15 0 0.961649 0

Members

Displaying 1 - 25 of 25
15950 interferon activated gene 203

Details for - - interferon activated gene 203

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15950

Tuberculist Genomic Region

170736 parvin, beta

Details for - - parvin, beta

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 170736

Tuberculist Genomic Region

19106 eukaryotic translation initiation factor 2-alpha kinase 2

Details for - - eukaryotic translation initiation factor 2-alpha kinase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19106

Tuberculist Genomic Region

19225 prostaglandin-endoperoxide synthase 2

Details for - - prostaglandin-endoperoxide synthase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19225

Tuberculist Genomic Region

19271 protein tyrosine phosphatase, receptor type, J

Details for RP24-113P16.2 - protein tyrosine phosphatase, receptor type, J

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19271

Tuberculist Genomic Region

19663 RNA binding protein gene with multiple splicing

Details for - - RNA binding protein gene with multiple splicing

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 19663

Tuberculist Genomic Region

20656 superoxide dismutase 2, mitochondrial

Details for - - superoxide dismutase 2, mitochondrial

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20656

Tuberculist Genomic Region

210106 PAP associated domain containing 7

Details for - - PAP associated domain containing 7

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 210106

Tuberculist Genomic Region

214133 tet methylcytosine dioxygenase 2

Details for - - tet methylcytosine dioxygenase 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 214133

Tuberculist Genomic Region

22169 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial

Details for - - cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22169

Tuberculist Genomic Region

22695 zinc finger protein 36

Details for - - zinc finger protein 36

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22695

Tuberculist Genomic Region

227449 zinc finger, CCHC domain containing 2

Details for - - zinc finger, CCHC domain containing 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 227449

Tuberculist Genomic Region

228994 YTH domain family 1

Details for RP23-359C15.7 - YTH domain family 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 228994

Tuberculist Genomic Region

231991 cAMP responsive element binding protein 5

Details for - - cAMP responsive element binding protein 5

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 231991

Tuberculist Genomic Region

241447 ceramide synthase 6

Details for RP23-431D4.1 - ceramide synthase 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 241447

Tuberculist Genomic Region

276950 schlafen 8

Details for RP23-392I13.9 - schlafen 8

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 276950

Tuberculist Genomic Region

56489 inhibitor of kappaB kinase epsilon

Details for - - inhibitor of kappaB kinase epsilon

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56489

Tuberculist Genomic Region

67916 phosphatidic acid phosphatase type 2B

Details for RP23-104G20.1 - phosphatidic acid phosphatase type 2B

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67916

Tuberculist Genomic Region

70675 valosin containing protein (p97)/p47 complex interacting protein 1

Details for - - valosin containing protein (p97)/p47 complex interacting protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 70675

Tuberculist Genomic Region

73914 interleukin-1 receptor-associated kinase 3

Details for - - interleukin-1 receptor-associated kinase 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 73914

Tuberculist Genomic Region

81702 ankyrin repeat domain 17

Details for - - ankyrin repeat domain 17

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 81702

Tuberculist Genomic Region

54396 immunity-related GTPase family M member 2

Details for RP24-499A8.1 - immunity-related GTPase family M member 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 54396

Tuberculist Genomic Region

13518 dystonin

Details for - - dystonin

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13518

Tuberculist Genomic Region

11796 baculoviral IAP repeat-containing 3

Details for RP24-318P17.1 - baculoviral IAP repeat-containing 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11796

Tuberculist Genomic Region

80750 NEDD4 binding protein 1

Details for - - NEDD4 binding protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 80750

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
Isgf3g.1 0.32 0.0000000519

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.00071 TCTKCYTCCTYC NA 7.3 RGRAAAACAAAA STAT1_MA0137.1, IRF1_MA0050.1

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
1.4 CGCGAA NA 1.55 NCGCGGAG NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.63 ATCCGT NA NA 0.72 GTTCCTNN mmu-mir-298-3p 7mer_m8

3p UTR PITA

miRNAs percTargets pValue
mmu-miR-1198 0.95 0.00000000857

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-5097 0.619048 0.00000037

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