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- negative regulation of transcription from RNA polymerase II promoter
- nuclear chromatin
- euchromatin
- heterochromatin
- core promoter proximal region sequence-specific DNA binding
- DNA binding
- ubiquitin-protein ligase activity
- protein binding
- nucleus
- replication fork
- nuclear heterochromatin
- DNA repair
- transcription, DNA-templated
- regulation of transcription, DNA-templated
- cellular response to DNA damage stimulus
- cell cycle
- zinc ion binding
- cell proliferation
- methyl-CpG binding
- maintenance of DNA methylation
- histone monoubiquitination
- nuclear matrix
- chromatin modification
- histone ubiquitination
- ligase activity
- nucleosomal histone binding
- positive regulation of cellular protein metabolic process
- methylated histone residue binding
- histone binding
- protein ubiquitination involved in ubiquitin-dependent protein catabolic process
- identical protein binding
- hemi-methylated DNA-binding
- metal ion binding
- protein autoubiquitination
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