Tgfbr1 transforming growth factor, beta receptor I (21812)

Symbol Product Feature Type Strand Chr
21812 Tgfbr1 transforming growth factor, beta receptor I protein-coding 4
Synonyms
ALK5 | AU017191 | Alk-5 | TbetaR-I | TbetaRI
GO ID Category Definition Evidence
  • nucleotide binding
  • activation of MAPKK activity
  • skeletal system development
  • angiogenesis
  • in utero embryonic development
  • kidney development
  • blastocyst development
  • epithelial to mesenchymal transition
  • negative regulation of endothelial cell proliferation
  • lens development in camera-type eye
  • protein kinase activity
  • protein serine/threonine kinase activity
  • transmembrane receptor protein serine/threonine kinase activity
  • transforming growth factor beta-activated receptor activity
  • transforming growth factor beta receptor activity, type I
  • type II transforming growth factor beta receptor binding
  • protein binding
  • ATP binding
  • plasma membrane
  • caveola
  • tight junction
  • regulation of transcription, DNA-templated
  • protein phosphorylation
  • apoptotic process
  • signal transduction
  • transmembrane receptor protein serine/threonine kinase signaling pathway
  • transforming growth factor beta receptor signaling pathway
  • heart development
  • positive regulation of cell proliferation
  • germ cell migration
  • embryo development
  • post-embryonic development
  • anterior/posterior pattern specification
  • regulation of gene expression
  • positive regulation of pathway-restricted SMAD protein phosphorylation
  • membrane
  • integral component of membrane
  • kinase activity
  • phosphorylation
  • basolateral plasma membrane
  • apical plasma membrane
  • transferase activity
  • transferase activity, transferring phosphorus-containing groups
  • peptidyl-serine phosphorylation
  • peptidyl-threonine phosphorylation
  • growth factor binding
  • cell junction
  • cell differentiation
  • collagen fibril organization
  • positive regulation of cell growth
  • regulation of protein ubiquitination
  • ubiquitin protein ligase binding
  • negative regulation of chondrocyte differentiation
  • protein complex binding
  • regulation of growth
  • negative regulation of apoptotic process
  • protein complex
  • receptor complex
  • regulation of protein binding
  • endothelial cell migration
  • response to estrogen
  • membrane raft
  • negative regulation of endothelial cell differentiation
  • positive regulation of transcription, DNA-templated
  • SMAD binding
  • protein autophosphorylation
  • metal ion binding
  • protein heterodimerization activity
  • thymus development
  • neuron fate commitment
  • embryonic cranial skeleton morphogenesis
  • skeletal system morphogenesis
  • artery morphogenesis
  • cell motility
  • transforming growth factor beta binding
  • positive regulation of cellular component movement
  • positive regulation of filopodium assembly
  • positive regulation of protein kinase B signaling
  • parathyroid gland development
  • palate development
  • pharyngeal system development
  • pathway-restricted SMAD protein phosphorylation
  • positive regulation of SMAD protein import into nucleus
  • I-SMAD binding
  • response to cholesterol
  • cellular response to transforming growth factor beta stimulus
  • positive regulation of apoptotic signaling pathway
  • negative regulation of extrinsic apoptotic signaling pathway
Motif 1 Motif 2 Residual
PITA_156 |
Residual: 
0.42
0.42
PITA_222 |
Residual: 
0.26
0.26
TargetScan_190 |
Residual: 
0.26
0.26
TargetScan_44 |
Residual: 
0.23
0.23
Displaying 1 - 4 of 4
Entrez ID STRINGS Network
STRING
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