TargetScan_44 megaCluster: 3 Residual: 0.23

Summary

Title Cluster Residual Bicluster Conditions Residual Permutation P-Value Var. Exp. First PC Var. Exp. First PC Perm. P-Value
TargetScan_44 3 0.23 15 0 0.893861 0

Members

Displaying 1 - 46 of 46
100034251 WAP four-disulfide core domain 17

Details for RP23-430I21.1 - WAP four-disulfide core domain 17

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 100034251

Tuberculist Genomic Region

13713 cholesterol 25-hydroxylase

Details for - - cholesterol 25-hydroxylase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12642

Tuberculist Genomic Region

15370 ELK3, member of ETS oncogene family

Details for - - ELK3, member of ETS oncogene family

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 13713

Tuberculist Genomic Region

15937 nuclear receptor subfamily 4, group A, member 1

Details for - - nuclear receptor subfamily 4, group A, member 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15370

Tuberculist Genomic Region

15945 immediate early response 3

Details for - - immediate early response 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15937

Tuberculist Genomic Region

16634 chemokine (C-X-C motif) ligand 10

Details for - - chemokine (C-X-C motif) ligand 10

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15945

Tuberculist Genomic Region

16819 killer cell lectin-like receptor, subfamily A, member 3

Details for - - killer cell lectin-like receptor, subfamily A, member 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16634

Tuberculist Genomic Region

170829 lipocalin 2

Details for RP23-161B9.11-003 - lipocalin 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16819

Tuberculist Genomic Region

21812 translocating chain-associating membrane protein 2

Details for - - translocating chain-associating membrane protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 170829

Tuberculist Genomic Region

231130 transforming growth factor, beta receptor I

Details for RP23-457P12.1 - transforming growth factor, beta receptor I

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 21812

Tuberculist Genomic Region

26362 TNFAIP3 interacting protein 2

Details for - - TNFAIP3 interacting protein 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 231130

Tuberculist Genomic Region

269593 AXL receptor tyrosine kinase

Details for - - AXL receptor tyrosine kinase

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 26362

Tuberculist Genomic Region

434223 leucine zipper protein 1

Details for RP23-426N4.1 - leucine zipper protein 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 269593

Tuberculist Genomic Region

544752 predicted gene 1966

Details for - - predicted gene 1966

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 434223

Tuberculist Genomic Region

56228 taurine upregulated gene 1

Details for - - taurine upregulated gene 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 544752

Tuberculist Genomic Region

56382 ubiquitin-conjugating enzyme E2J 1

Details for RP23-12I24.8 - ubiquitin-conjugating enzyme E2J 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56228

Tuberculist Genomic Region

666737 RAB9, member RAS oncogene family

Details for RP23-408K4.3 - RAB9, member RAS oncogene family

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 56382

Tuberculist Genomic Region

667281 RIKEN cDNA 4632427E13 gene

Details for - - RIKEN cDNA 4632427E13 gene

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 666737

Tuberculist Genomic Region

67224 histocompatibility 60b

Details for - - histocompatibility 60b

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 667281

Tuberculist Genomic Region

71436 mediator complex subunit 29

Details for - - mediator complex subunit 29

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67224

Tuberculist Genomic Region

71623 fibronectin leucine rich transmembrane protein 3

Details for RP23-388J20.1 - fibronectin leucine rich transmembrane protein 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71436

Tuberculist Genomic Region

73998 keratin associated protein 5-2

Details for - - keratin associated protein 5-2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 71623

Tuberculist Genomic Region

78943 hect domain and RLD 3

Details for - - hect domain and RLD 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 73998

Tuberculist Genomic Region

80752 endoplasmic reticulum (ER) to nucleus signalling 1

Details for RP23-418O11.11-001 - endoplasmic reticulum (ER) to nucleus signalling 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 78943

Tuberculist Genomic Region

12864 family with sequence similarity 20, member C

Details for - - family with sequence similarity 20, member C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 80752

Tuberculist Genomic Region

232065 cytochrome c oxidase subunit VIc

Details for - - cytochrome c oxidase subunit VIc

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12864

Tuberculist Genomic Region

73914 immunoglobulin kappa variable 8-19

Details for - - immunoglobulin kappa variable 8-19

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 232065

Tuberculist Genomic Region

105559 interleukin-1 receptor-associated kinase 3

Details for - - interleukin-1 receptor-associated kinase 3

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 73914

Tuberculist Genomic Region

12874 muscleblind-like 2

Details for - - muscleblind-like 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 105559

Tuberculist Genomic Region

16181 carboxypeptidase D

Details for RP23-396O3.1 - carboxypeptidase D

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 12874

Tuberculist Genomic Region

16449 interleukin 1 receptor antagonist

Details for RP23-218B17.2 - interleukin 1 receptor antagonist

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16181

Tuberculist Genomic Region

20482 jagged 1

Details for RP23-173O12.3 - jagged 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 16449

Tuberculist Genomic Region

209630 SKI-like

Details for - - SKI-like

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 20482

Tuberculist Genomic Region

212943 FERM domain containing 4A

Details for RP23-198D21.2 - FERM domain containing 4A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 209630

Tuberculist Genomic Region

22146 family with sequence similarity 46, member A

Details for - - family with sequence similarity 46, member A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 212943

Tuberculist Genomic Region

269181 tubulin, alpha 1C

Details for - - tubulin, alpha 1C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 22146

Tuberculist Genomic Region

269966 mannoside acetylglucosaminyltransferase 4, isoenzyme A

Details for - - mannoside acetylglucosaminyltransferase 4, isoenzyme A

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 269181

Tuberculist Genomic Region

432486 nucleoporin 98

Details for - - nucleoporin 98

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 269966

Tuberculist Genomic Region

67712 N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

Details for - - N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 432486

Tuberculist Genomic Region

80719 solute carrier family 25, member 37

Details for - - solute carrier family 25, member 37

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 67712

Tuberculist Genomic Region

11787 immunoglobulin superfamily, member 6

Details for - - immunoglobulin superfamily, member 6

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 80719

Tuberculist Genomic Region

15957 amyloid beta (A4) precursor protein-binding, family B, member 2

Details for - - amyloid beta (A4) precursor protein-binding, family B, member 2

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 11787

Tuberculist Genomic Region

60533 interferon-induced protein with tetratricopeptide repeats 1

Details for - - interferon-induced protein with tetratricopeptide repeats 1

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 15957

Tuberculist Genomic Region

74645 CD274 antigen

Details for - - CD274 antigen

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 60533

Tuberculist Genomic Region

80910 family with sequence similarity 46, member C

Details for DN-384L23.3 - family with sequence similarity 46, member C

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 74645

Tuberculist Genomic Region

Details for - - G protein-coupled receptor 84

GO Terms: NA

PATRIC Pathways: [field_patric_pathways]

Essentiality: Griffin Essential: [field_griffin_essential] | In vitro Essential: [field_in_vitro_essential] | In vivo Essential: [field_in_vivo_essential]

Go to Gene Page: 80910

Tuberculist Genomic Region

TFBS DB TF

TFs percTargets pValue
Foxj3_forkhead_DBD_putatively-multimeric_11_1 0.162791 0.0000178

GO Terms

Displaying 1 - 1 of 1
GO Terms
NA

Upstream MEME Motif

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif2 E-Value Motif2 Consensus Motif2 Matches
0.000000000027 AARAARAAAAAA NA 200 AAAGTGAAACTT STAT1_MA0137.1, IRF2_MA0051.1, IRF1_MA0050.1, V$ISRE_01_M00258, V$IRF1_Q6_01_M01881, V$ICSBP_Q6_M00699, V$IRF8_Q6_M01665, V$IRF2_01_M00063, V$IRF1_01_M00062

Upstream Weeder Motif

Motif1 Score Motif1 Consensus Motif1 Matches Motif2 Score Motif2 Consensus Motif2 Matches
0.87 TCGCCG NA 0.81 CGCGCTGT NA

3p UTR Weeder

Motif1 E-Value Motif1 Consensus Motif1 Matches Motif1 Model Motif2 E-Value Motif2 Consensus Motif2 Matches Motif2 Model
0.4 ACGTAC NA NA 0.66 GTAMGACG NA NA

3p UTR PITA

miRNAs percTargets pValue
NA

3p UTR TargetScan

miRNAs percTargets pValue
mmu-miR-338-5p 0.428571 0.0000382

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