Rv1647 Purine cyclase-related protein
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.01 for bicluster_0324 and 410.00 and 4,100.00 for bicluster_0518 respectively.
These modules are enriched for following go terms: peptidoglycan metabolic process, aminoglycan metabolic process, glycosaminoglycan metabolic process.
This gene is found to be for growth on cholesterol.
Mutant available?: Yes
|BASS Score||Distance to Tuberculist Start Codon||Internal TSS||New Primary UTR||Primary TSS||Re-Annotated Start||Tuberculist Annotated Start|
|Product (LegacyBRC)||Product (RefSeq)|
|Putative uncharacterized protein|
|BioCyc Gene Page||Cellular Overview Map|
magnesium ion binding
adenylate cyclase activity
manganese ion binding
Quantitative Proteomics Data
TRIP log2 fold abundance change
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.