Module 218 Residual: 0.55

Title Bicluster Model Residual Score
bicluster_0218 v02 0.55 -23.39
Displaying 1 - 14 of 14
Rv0069c L-serine dehydratase (EC 4.3.1.17)

Details for Rv0069c - L-serine dehydratase (EC 4.3.1.17)

GO Terms: GO:0005886

PATRIC Pathways: Cysteine and methionine metabolism, Glycine, serine and threonine metabolism

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0069c

Tuberculist Genomic Region

Rv0070c Serine hydroxymethyltransferase (EC 2.1.2.1)

Details for Rv0070c - Serine hydroxymethyltransferase (EC 2.1.2.1)

GO Terms: GO:0004372

PATRIC Pathways: Methane metabolism, Glycine, serine and threonine metabolism, Cyanoamino acid metabolism, One carbon pool by folate

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0070c

Tuberculist Genomic Region

Rv0500 Pyrroline-5-carboxylate reductase (EC 1.5.1.2)

Details for Rv0500 - Pyrroline-5-carboxylate reductase (EC 1.5.1.2)

GO Terms: GO:0004735, GO:0005886, GO:0040007

PATRIC Pathways: Arginine and proline metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv0500

Tuberculist Genomic Region

Rv1141c Enoyl-CoA hydratase (EC 4.2.1.17)
Rv1143 Alpha-methylacyl-CoA racemase (EC 5.1.99.4)

Details for Rv1143 - Alpha-methylacyl-CoA racemase (EC 5.1.99.4)

GO Terms: GO:0008111, GO:0042803

PATRIC Pathways: Primary bile acid biosynthesis

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1143

Tuberculist Genomic Region

Rv1144 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)

Details for Rv1144 - 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)

GO Terms: GO:0005886

PATRIC Pathways: Primary bile acid biosynthesis, Valine, leucine and isoleucine degradation, Caprolactam degradation, Fatty acid elongation in mitochondria, Fatty acid metabolism, Reductive carboxylate cycle (CO2 fixation), Lysine degradation, 2,4-Dichlorobenzoate degradation, Butanoate metabolism, Geraniol degradation, Tryptophan metabolism

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: 0.35

Go to Gene Page: Rv1144

Tuberculist Genomic Region

Rv1261c

Details for Rv1261c -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1261c

Tuberculist Genomic Region

Rv1262c Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17)

Details for Rv1262c - Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17)

GO Terms: NA

PATRIC Pathways: Purine metabolism, Pyrimidine metabolism

Essentiality: Griffin Essential: 0.86 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1262c

Tuberculist Genomic Region

Rv1556 Transcriptional regulator, TetR family

Details for Rv1556 - Transcriptional regulator, TetR family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1556

Tuberculist Genomic Region

Rv3788 Nucleoside diphosphate kinase regulator

Details for Rv3788 - Nucleoside diphosphate kinase regulator

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3788

Tuberculist Genomic Region

Rv0739

Details for Rv0739 -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0739

Tuberculist Genomic Region

Rv1142c Enoyl-CoA hydratase (EC 4.2.1.17)
Rv1896c Putative S-adenosyl-L-methionine-dependent methyltransferase

Details for Rv1896c - Putative S-adenosyl-L-methionine-dependent methyltransferase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.15 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1896c

Tuberculist Genomic Region

Rv3787c

Details for Rv3787c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3787c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.000000000032 e-value: 0.000022
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 9 of 9
GO:0005886 |

plasma membrane

GO:0004372 |

glycine hydroxymethyltransferase activity

GO:0004735 |

pyrroline-5-carboxylate reductase activity

GO:0040007 |

growth

GO:0004300 |

enoyl-CoA hydratase activity

GO:0008111 |

alpha-methylacyl-CoA racemase activity

GO:0042803 |

protein homodimerization activity

GO:0005829 |

cytosol