P9WGG3 cobB, sir2, Rv1151c, MTCI65.18c
Source: Uniprot proteome:up000001584
Binding Site | Subcellular location |
---|---|
53 53 Substrate (By similarity)., 56 56 Substrate (By similarity)., 221 221 NAD, via amide nitrogen (By similarity). | Cytoplasm (By similarity). |
Domain | Domain Extent | InterPro | Pfam | ProDom | Region | Similarity | SUPFAM |
---|---|---|---|---|---|---|---|
2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity (By similarity). | DOMAIN 1 237 Deacetylase sirtuin-type. | PF02146 | Belongs to the sirtuin family. Class III subfamily., Contains 1 deacetylase sirtuin-type domain. |
SSGCID ID |
---|
PDB | Protein Model Portal |
---|---|
EC number | KEGG KO | UniPathway |
---|---|---|
3.5.1.- |
HOGENOM | KEGG KO | OMA | OrthoDB |
---|---|---|---|