O53590 sigM, Rv3911

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
O53590 SIGM_MYCTU
RNA polymerase sigma-70 factor, ECF subfamily
ECF RNA polymerase sigma factor SigM (ECF sigma factor SigM) (Alternative RNA polymerase sigma factor SigM) (RNA polymerase sigma-M factor) (Sigma-M factor) 9634230, 10027986, 17028284, 16735723, 19099550, 22733573 sigM sigM, Rv3911 CCP46740,
Domain InterPro Pfam ProDom Region Similarity SUPFAM
The sigma-70 factor domain-2 mediates sequence-specific interaction with the -10 element in promoter DNA, and plays an important role in melting the double-stranded DNA and the formation of the transcription bubble. The sigma-70 factor domain-2 mediates interaction with the RNA polymerase subunits RpoB and RpoC (By similarity).; The sigma-70 factor domain-4 contains a helix-turn-helix (H-T-H) motif that mediates interaction with the -35 element in promoter DNA. The domain also mediates interaction with the RNA polymerase subunit RpoA. Interactions between sigma-70 factor domain-4 and anti-sigma factors prevents interaction of sigma factors with the RNA polymerase catalytic core (By similarity). PF04542, PF08281 Belongs to the sigma-70 factor family. ECF subfamily. SSF88659, SSF88946
Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
1.10.10.10, PF04542, PF08281 SSF88659, SSF88946
PDB Protein Model Portal
EC number KEGG KO UniPathway
K03088,
HOGENOM KEGG KO OMA OrthoDB
HOG000094755, K03088, EOG6ZD6DW,