P9WFS9 valS, Rv2448c, MTV008.04c

Summary

Source: Uniprot proteome:up000001584

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WFS9 SYV_MYCTU
Rv2448c
Valyl-tRNA synthetase (EC 6.1.1.9)
 MTV008.04c Valine--tRNA ligase (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS) 9634230 valS valS, Rv2448c, MTV008.04c

Last update: 06/10/2014

Structure Details

Binding Site Subcellular location
533 533 ATP (By similarity). Cytoplasm (By similarity).

Domain/Family Details

Domain InterPro Pfam ProDom Region Similarity SUPFAM
ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site (By similarity).; The C-terminal coiled-coil domain is crucial for aminoacylation activity (By similarity). PF08264, PF00133, PF10458 Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. SSF46589, SSF47323, SSF50677

Domain/Family DBs

Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
1.10.287.380, 1.10.730.10, 3.40.50.620, 3.90.740.10, MF_02004, PF08264, PF00133, PF10458 PR00986, PS00178 SSF46589, SSF47323, SSF50677

SSGCID Target Details

SSGCID ID

3D Details

PDB Protein Model Portal

Pathway Details

EC number KEGG KO UniPathway
6.1.1.9

Phylogenetic

HOGENOM KEGG KO OMA OrthoDB