P9WGG7 sigE, Rv1221
Source: Uniprot proteome:up000001584
| Title | id | ORF names | Protein names | PubMed ID | Short | Synonyms | EnsemblBacteria |
|---|---|---|---|---|---|---|---|
| P9WGG7 SIGE_MYCTU | ECF RNA polymerase sigma factor SigE (ECF sigma factor SigE) (Alternative RNA polymerase sigma factor SigE) (RNA polymerase sigma-E factor) (Sigma-E factor) | 9139909, 9634230, 10027986, 11567012, 11489128, 11929527, 15102817, 16513743, 17379732, 18657035, 18606740, 20025669 | sigE | sigE, Rv1221 |
| Domain | InterPro | Pfam | ProDom | Region | Similarity | SUPFAM |
|---|---|---|---|---|---|---|
| The sigma-70 factor domain-2 mediates sequence-specific interaction with the -10 element in promoter DNA, and plays an important role in melting the double-stranded DNA and the formation of the transcription bubble. The sigma-70 factor domain-2 mediates interaction with the RNA polymerase subunits RpoB and RpoC (By similarity).; The sigma-70 factor domain-4 contains a helix-turn-helix (H-T-H) motif that mediates interaction with the -35 element in promoter DNA. The domain also mediates interaction with the RNA polymerase subunit RpoA. Interactions between sigma-70 factor domain-4 and anti-sigma factors prevents interaction of sigma factors with the RNA polymerase catalytic core (Probable). | PF04542, PF08281 | Belongs to the sigma-70 factor family. ECF subfamily. | SSF88659, SSF88946 |
| SSGCID ID |
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| PDB | Protein Model Portal |
|---|---|
| EC number | KEGG KO | UniPathway |
|---|---|---|
| HOGENOM | KEGG KO | OMA | OrthoDB |
|---|---|---|---|