P9WGG7 sigE, Rv1221

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WGG7 SIGE_MYCTU
RNA polymerase sigma-70 factor, ECF subfamily
ECF RNA polymerase sigma factor SigE (ECF sigma factor SigE) (Alternative RNA polymerase sigma factor SigE) (RNA polymerase sigma-E factor) (Sigma-E factor) 9139909, 9634230, 10027986, 11567012, 11489128, 11929527, 15102817, 16513743, 17379732, 18657035, 18606740, 20025669 sigE sigE, Rv1221
Domain InterPro Pfam ProDom Region Similarity SUPFAM
The sigma-70 factor domain-2 mediates sequence-specific interaction with the -10 element in promoter DNA, and plays an important role in melting the double-stranded DNA and the formation of the transcription bubble. The sigma-70 factor domain-2 mediates interaction with the RNA polymerase subunits RpoB and RpoC (By similarity).; The sigma-70 factor domain-4 contains a helix-turn-helix (H-T-H) motif that mediates interaction with the -35 element in promoter DNA. The domain also mediates interaction with the RNA polymerase subunit RpoA. Interactions between sigma-70 factor domain-4 and anti-sigma factors prevents interaction of sigma factors with the RNA polymerase catalytic core (Probable). PF04542, PF08281 Belongs to the sigma-70 factor family. ECF subfamily. SSF88659, SSF88946
Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
1.10.10.10, PF04542, PF08281 SSF88659, SSF88946
PDB Protein Model Portal
EC number KEGG KO UniPathway
HOGENOM KEGG KO OMA OrthoDB