P9WGG9 sigD, Rv3414c, MTCY78.15
Source: Uniprot proteome:up000001584
Title | id | ORF names | Protein names | PubMed ID | Short | Synonyms | EnsemblBacteria |
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P9WGG9 RPSD_MYCTU | MTCY78.15 | ECF RNA polymerase sigma factor SigD (ECF sigma factor SigD) (Alternative RNA polymerase sigma factor SigD) (RNA polymerase sigma-D factor) (Sigma-D factor) | 9634230, 10027986, 15375142, 20600947, 23314154 | sigD | sigD, Rv3414c, MTCY78.15 |
Domain | InterPro | Pfam | ProDom | Region | Similarity | SUPFAM |
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The sigma-70 factor domain-2 mediates sequence-specific interaction with the -10 element in promoter DNA, and plays an important role in melting the double-stranded DNA and the formation of the transcription bubble. The sigma-70 factor domain-2 mediates interaction with the RNA polymerase subunits RpoB and RpoC (By similarity).; The sigma-70 factor domain-4 contains a helix-turn-helix (H-T-H) motif that mediates interaction with the -35 element in promoter DNA. The domain also mediates interaction with the RNA polymerase subunit RpoA. Interactions between sigma-70 factor domain-4 and anti-sigma factors prevents interaction of sigma factors with the RNA polymerase catalytic core (By similarity). | PF04542, PF08281 | Belongs to the sigma-70 factor family. ECF subfamily. | SSF88659, SSF88946 |
SSGCID ID |
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PDB | Protein Model Portal |
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EC number | KEGG KO | UniPathway |
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HOGENOM | KEGG KO | OMA | OrthoDB |
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