P9WGH5 sigL, Rv0735
Source: Uniprot proteome:up000001584
| Title | id | ORF names | Protein names | PubMed ID | Short | Synonyms | EnsemblBacteria |
|---|---|---|---|---|---|---|---|
| P9WGH5 SIGL_MYCTU | ECF RNA polymerase sigma factor SigL (ECF sigma factor SigL) (Alternative RNA polymerase sigma factor SigL) (RNA polymerase sigma-L factor) (Sigma-L factor) | 9634230, 16199577, 16552079, 20600947, 20184899 | sigL | sigL, Rv0735 |
| Domain | InterPro | Pfam | ProDom | Region | Similarity | SUPFAM |
|---|---|---|---|---|---|---|
| The sigma-70 factor domain-2 mediates sequence-specific interaction with the -10 element in promoter DNA, and plays an important role in melting the double-stranded DNA and the formation of the transcription bubble. The sigma-70 factor domain-2 mediates interaction with the RNA polymerase subunits RpoB and RpoC (By similarity).; The sigma-70 factor domain-4 contains a helix-turn-helix (H-T-H) motif that mediates interaction with the -35 element in promoter DNA. The domain also mediates interaction with the RNA polymerase subunit RpoA. Interactions between sigma-70 factor domain-4 and anti-sigma factors prevents interaction of sigma factors with the RNA polymerase catalytic core (Probable). | PF04542, PF04545 | Belongs to the sigma-70 factor family. ECF subfamily. | SSF88659, SSF88946 |
| SSGCID ID |
|---|
| PDB | Protein Model Portal |
|---|---|
| EC number | KEGG KO | UniPathway |
|---|---|---|
| HOGENOM | KEGG KO | OMA | OrthoDB |
|---|---|---|---|