P9WGH7 sigK, Rv0445c

Summary

Source: Uniprot proteome:up000001584

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WGH7 SIGK_MYCTU
Rv0445c
RNA polymerase sigma factor RpoE
 ECF RNA polymerase sigma factor SigK (ECF sigma factor SigK) (Alternative RNA polymerase sigma factor SigK) (RNA polymerase sigma-K factor) (Sigma-K factor) 9634230, 15882422, 20600947, sigK sigK, Rv0445c

Last update: 06/10/2014

Structure Details

Domain/Family Details

Domain InterPro Pfam ProDom Region Similarity SUPFAM
The sigma-70 factor domain-2 mediates sequence-specific interaction with the -10 element in promoter DNA, and plays an important role in melting the double-stranded DNA and the formation of the transcription bubble. The sigma-70 factor domain-2 mediates interaction with the RNA polymerase subunits RpoB and RpoC (By similarity).; The sigma-70 factor domain-4 contains a helix-turn-helix (H-T-H) motif that mediates interaction with the -35 element in promoter DNA. The domain also mediates interaction with the RNA polymerase subunit RpoA. Interactions between sigma-70 factor domain-4 and anti-sigma factors prevents interaction of sigma factors with the RNA polymerase catalytic core (By similarity). PF04542, PF04545 Belongs to the sigma-70 factor family. ECF subfamily. SSF88659, SSF88946

Domain/Family DBs

Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
1.10.10.10, PF04542, PF04545 SSF88659, SSF88946

SSGCID Target Details

SSGCID ID

3D Details

PDB Protein Model Portal

Pathway Details

EC number KEGG KO UniPathway

Phylogenetic

HOGENOM KEGG KO OMA OrthoDB