P9WGH9 sigH, rpoE, Rv3223c, MTCY07D11.03
Source: Uniprot proteome:up000001584
Title | id | ORF names | Protein names | PubMed ID | Short | Synonyms | EnsemblBacteria |
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P9WGH9 SIGH_MYCTU | MTCY07D11.03 | ECF RNA polymerase sigma factor SigH (ECF sigma factor SigH) (Alternative RNA polymerase sigma factor SigH) (RNA polymerase sigma-H factor) (Sigma-H factor) | 9634230, 22937074, 10027986, 11567012, 12123450, 14617153, 16298337, 19099550, 18728196 | sigH | sigH, rpoE, Rv3223c, MTCY07D11.03 |
Domain | InterPro | Pfam | ProDom | Region | Similarity | SUPFAM |
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The sigma-70 factor domain-2 mediates sequence-specific interaction with the -10 element in promoter DNA, and plays an important role in melting the double-stranded DNA and the formation of the transcription bubble. The sigma-70 factor domain-2 mediates interaction with the RNA polymerase subunits RpoB and RpoC (By similarity).; The sigma-70 factor domain-4 contains a helix-turn-helix (H-T-H) motif that mediates interaction with the -35 element in promoter DNA. The domain also mediates interaction with the RNA polymerase subunit RpoA. Interactions between sigma-70 factor domain-4 and anti-sigma factors prevents interaction of sigma factors with the RNA polymerase catalytic core. | PF04542, PF08281 | Belongs to the sigma-70 factor family. ECF subfamily. | SSF88659, SSF88946 |
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PDB | Protein Model Portal |
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EC number | KEGG KO | UniPathway |
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HOGENOM | KEGG KO | OMA | OrthoDB |
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