P9WGI3 sigF, Rv3286c
Source: Uniprot proteome:up000001584
Title | id | ORF names | Protein names | PubMed ID | Short | Synonyms | EnsemblBacteria |
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P9WGI3 SIGF_MYCTU | RNA polymerase sigma factor SigF (Sigma factor SigF) (Alternative RNA polymerase sigma factor SigF) (RNA polymerase sigma-F factor) (Sigma-F factor) (Stress response | 8610119, 9634230, 10027986, 11929527, 12354223, 16735723, 19130906, 20729364, 20600947, 22307756, 22570422 | sigF | sigF, Rv3286c |
Domain | InterPro | Pfam | ProDom | Region | Similarity | SUPFAM |
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The sigma-70 factor domain-2 mediates sequence-specific interaction with the -10 element in promoter DNA, and plays an important role in melting the double-stranded DNA and the formation of the transcription bubble. The sigma-70 factor domain-2 mediates interaction with the RNA polymerase subunits RpoB and RpoC (By similarity).; The sigma-70 factor domain-4 contains a helix-turn-helix (H-T-H) motif that mediates interaction with the -35 element in promoter DNA. The domain also mediates interaction with the RNA polymerase subunit RpoA. Interactions between sigma-70 factor domain-4 and anti-sigma factors prevents interaction of sigma factors with the RNA polymerase catalytic core (By similarity). | PF04542, PF04539, PF04545 | Belongs to the sigma-70 factor family. | SSF88659, SSF88946 |
SSGCID ID |
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PDB | Protein Model Portal |
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EC number | KEGG KO | UniPathway |
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HOGENOM | KEGG KO | OMA | OrthoDB |
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