P9WHF1 ribBA, ribA, ribA2, Rv1415, MTCY21B4.33 | MTB Network Portal

Summary

Source: Uniprot proteome:up000001584

Title	id	ORF names	Protein names	PubMed ID	Short	Synonyms	EnsemblBacteria
P9WHF1 RIBBA_MYCTU	Rv1415 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II (EC 3.5.4.25)	MTCY21B4.33	Riboflavin biosynthesis protein RibBA [Includes: 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP synthase) (EC 4.1.99.12); GTP cyclohydrolase-2 (EC 3.5.4.25) (GTP cyclohydrolase II)]	9634230	ribBA	ribBA, ribA, ribA2, Rv1415, MTCY21B4.33

Structure Details

Binding Site
33 33 D-ribulose 5-phosphate (By similarity)., 165 165 D-ribulose 5-phosphate (By similarity)., 280 280 GTP (By similarity)., 325 325 GTP (By similarity)., 360 360 GTP (By similarity)., 365 365 GTP (By similarity).

Domain/Family Details

InterPro	Pfam	ProDom	Region	Similarity	SUPFAM
	PF00926, PF00925			In the N-terminal section, belongs to the DHBP synthase family., In the C-terminal section, belongs to the GTP cyclohydrolase II family.	SSF55821

Domain/Family DBs

Gene3D	HAMAP	PANTHER	Pfam	PIRSF	PRINTS	ProDom	PROSITE	SMART	SUPFAM
3.90.870.10,	MF_00179, MF_00180, MF_01283,		PF00926, PF00925	PIRSF001259,					SSF55821

SSGCID Target Details

SSGCID ID

3D Details

PDB	Protein Model Portal

Pathway Details

EC number	KEGG KO	UniPathway
4.1.99.12, 3.5.4.25		Cofactor biosynthesis, riboflavin biosynthesis, 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1., Cofactor biosynthesis, riboflavin biosynthesis, 5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4.

Phylogenetic

HOGENOM	KEGG KO	OMA	OrthoDB