P9WHU9 proB, Rv2439c, MTCY428.07 | MTB Network Portal

Summary

Source: Uniprot proteome:up000001584

Title	id	ORF names	Protein names	PubMed ID	Short	Synonyms	EnsemblBacteria
P9WHU9 PROB_MYCTU	Rv2439c Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA	MTCY428.07	Glutamate 5-kinase (EC 2.7.2.11) (Gamma-glutamyl kinase) (GK)	9634230, 19099550	proB	proB, Rv2439c, MTCY428.07

Structure Details

Binding Site	Subcellular location
18 18 ATP (By similarity)., 58 58 Substrate (By similarity)., 145 145 Substrate (By similarity)., 157 157 Substrate, via amide nitrogen (By similarity).	Cytoplasm (By similarity).

Domain/Family Details

Domain Extent	InterPro	Pfam	ProDom	Region	Similarity	SUPFAM
DOMAIN 280 358 PUA.		PF00696, PF01472			Belongs to the glutamate 5-kinase family., Contains 1 PUA domain.	SSF53633, SSF88697

Domain/Family DBs

Gene3D	HAMAP	PANTHER	Pfam	PIRSF	PRINTS	ProDom	PROSITE	SMART	SUPFAM
2.30.130.10, 3.40.1160.10,	MF_00456,		PF00696, PF01472	PIRSF000729,	PR00474,		PS00902, PS50890	SM00359,	SSF53633, SSF88697

SSGCID Target Details

SSGCID ID

3D Details

PDB	Protein Model Portal

Pathway Details

EC number	KEGG KO	UniPathway
2.7.2.11		Amino-acid biosynthesis, L-proline biosynthesis, L-glutamate 5-semialdehyde from L-glutamate: step 1/2.

Phylogenetic

HOGENOM	KEGG KO	OMA	OrthoDB