P9WJL3 murE, Rv2158c, MTCY270.10

Summary

Source: Uniprot proteome:up000001584

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WJL3 MURE_MYCTU
Rv2158c
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13)
 MTCY270.10 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (EC 6.3.2.13) (Meso-A2pm-adding enzyme) (Meso-diaminopimelate-adding enzyme) (UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase) (UDP-MurNAc-tripeptide synthetase) (UDP-N-acetylmuramyl-tripeptide synthetase) 9634230, 19099550 murE murE, Rv2158c, MTCY270.10

Last update: 06/10/2014

Structure Details

Binding Site Subcellular location
67 67 UDP-MurNAc-L-Ala-D-Glu, via carbonyl oxygen (By similarity)., 222 222 UDP-MurNAc-L-Ala-D-Glu (By similarity)., 230 230 UDP-MurNAc-L-Ala-D-Glu (By similarity)., 424 424 Meso-diaminopimelate (By similarity)., 502 502 Meso-diaminopimelate, via carbonyl oxygen (By similarity)., 506 506 Meso-diaminopimelate (By similarity). Cytoplasm (By similarity).

Domain/Family Details

InterPro Pfam ProDom Region Similarity SUPFAM
PF01225, PF02875, PF08245 Belongs to the MurCDEF family. MurE subfamily. SSF53244, SSF53623, SSF63418

Domain/Family DBs

Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
3.40.1190.10, 3.40.1390.10, 3.90.190.20, MF_00208, PF01225, PF02875, PF08245 SSF53244, SSF53623, SSF63418

SSGCID Target Details

SSGCID ID

3D Details

PDB Protein Model Portal

Pathway Details

EC number KEGG KO UniPathway
6.3.2.13 Cell wall biogenesis, peptidoglycan biosynthesis.

Phylogenetic

HOGENOM KEGG KO OMA OrthoDB