P9WMP7 hemA, Rv0509, MTCY20G9.36
Source: Uniprot proteome:up000001584
| Binding Site |
|---|
| 109 109 Substrate (By similarity)., 120 120 Substrate (By similarity). |
| Domain | InterPro | Pfam | ProDom | Region | Similarity | SUPFAM |
|---|---|---|---|---|---|---|
| Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization (By similarity). | PF00745, PF05201, PF01488 | Belongs to the glutamyl-tRNA reductase family. | SSF69075, SSF69742 |
| SSGCID ID |
|---|
| PDB | Protein Model Portal |
|---|---|
| EC number | KEGG KO | UniPathway |
|---|---|---|
| 1.2.1.70 | Porphyrin-containing compound metabolism, protoporphyrin-IX biosynthesis, 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2. |
| HOGENOM | KEGG KO | OMA | OrthoDB |
|---|---|---|---|