P9WMP7 hemA, Rv0509, MTCY20G9.36

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WMP7 HEM1_MYCTU
Glutamyl-tRNA reductase (EC 1.2.1.70)
MTCY20G9.36 Glutamyl-tRNA reductase (GluTR) (EC 1.2.1.70) 9634230, 19099550 hemA hemA, Rv0509, MTCY20G9.36
Binding Site
109 109 Substrate (By similarity)., 120 120 Substrate (By similarity).
Domain InterPro Pfam ProDom Region Similarity SUPFAM
Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization (By similarity). PF00745, PF05201, PF01488 Belongs to the glutamyl-tRNA reductase family. SSF69075, SSF69742
Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
3.40.50.720, MF_00087, PF00745, PF05201, PF01488 PIRSF000445, PS00747 SSF69075, SSF69742
PDB Protein Model Portal
HOGENOM KEGG KO OMA OrthoDB