P9WMU9 Rv1264, MTCY50.18c

Summary

Source: Uniprot proteome:up000001584

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WMU9 Y1264_MYCTU
Rv1264
Adenylate cyclase (EC 4.6.1.1)
 MTCY50.18c pH-sensitive adenylate cyclase Rv1264 (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase) 9634230, 11416222, 11839758, 19099550, 17005450, 15890882, 17482646 Rv1264, MTCY50.18c

Last update: 06/10/2014

Structure Details

Binding Site
261 261 Substrate (Probable)., 298 298 ATP (Probable)., 312 312 Substrate (Probable).

Domain/Family Details

Domain Domain Extent InterPro Pfam ProDom Region Similarity SUPFAM
Consists of 3 structural domains. The pH-responsive N-terminus inhibits the adenylyl cyclase (AC) activity of the C-terminal catalytic domain. The length of the linker segment (aa 192-206) is decisive for regulation. DOMAIN 217 325 Guanylate cyclase. PF00211 Belongs to the adenylyl cyclase class-4/guanylyl cyclase family., Contains 1 guanylate cyclase domain. SSF55073

Domain/Family DBs

Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
3.30.70.1230, PF00211 PS50125 SM00044, SSF55073

SSGCID Target Details

SSGCID ID

3D Details

PDB Protein Model Portal

Pathway Details

EC number KEGG KO UniPathway
4.6.1.1

Phylogenetic

HOGENOM KEGG KO OMA OrthoDB