P9WPX3 ask, Rv3709c, MTV025.057c | MTB Network Portal

Summary

Source: Uniprot proteome:up000001584

Title	id	ORF names	Protein names	PubMed ID	Short	Synonyms	EnsemblBacteria
P9WPX3 AK_MYCTU	Rv3709c Aspartokinase (EC 2.7.2.4)	MTV025.057c	Aspartokinase (EC 2.7.2.4) (Aspartate kinase) (ASK)	9634230, 21393848, 21976064	ask	ask, Rv3709c, MTV025.057c

Structure Details

Binding Site
41 41 ATP (By similarity)., 74 74 Substrate (By similarity)., 154 154 Substrate (By similarity)., 210 210 ATP (By similarity)., 274 274 Substrate (By similarity)., 298 298 Substrate (By similarity).

Domain/Family Details

Domain Extent	InterPro	Pfam	ProDom	Region	Similarity	SUPFAM
DOMAIN 267 348 ACT 1., DOMAIN 349 421 ACT 2.		PF00696, PF01842, PF13840			Belongs to the aspartokinase family., Contains 2 ACT domains.	SSF53633

Domain/Family DBs

Gene3D	HAMAP	PANTHER	Pfam	PIRSF	PRINTS	ProDom	PROSITE	SMART	SUPFAM
3.40.1160.10,			PF00696, PF01842, PF13840	PIRSF000726,			PS51671, PS00324		SSF53633

SSGCID Target Details

SSGCID ID

3D Details

PDB	Protein Model Portal

Pathway Details

EC number	KEGG KO	UniPathway
2.7.2.4		Amino-acid biosynthesis, L-lysine biosynthesis via DAP pathway, (S)-tetrahydrodipicolinate from L-aspartate: step 1/4., Amino-acid biosynthesis, L-methionine biosynthesis via de novo pathway, L-homoserine from L-aspartate: step 1/3., Amino-acid biosynthesis, L-threonine biosynthesis, L-threonine from L-aspartate: step 1/5.

Phylogenetic

HOGENOM	KEGG KO	OMA	OrthoDB