P9WQ63 mbtB, Rv2383c

Summary

Source: Uniprot proteome:up000001584

Title id ORF names Protein names PubMed ID Short Synonyms EnsemblBacteria
P9WQ63 MBTB_MYCTU
Rv2383c
Phenyloxazoline synthase MbtB (EC 6.3.2.-)
 Phenyloxazoline synthase MbtB (EC 6.3.2.-) (Mycobactin synthetase protein B) 9634230, 10655517, 11722747 mbtB mbtB, Rv2383c

Last update: 06/10/2014

Structure Details

Domain/Family Details

Domain Domain Extent InterPro Pfam ProDom Region Similarity SUPFAM
Modular protein that contains an aryl carrier protein (ArCP) domain which bears a phosphopantetheinyl arm to attach the activated salicylic acid, a condensation/cyclization domain involved in the formation of the oxazoline ring, an adenylation domain which activates the serine or threonine residue into an aminoacyl-AMP ester, a peptidyl carrier protein (PCP) domain which bears a phosphopantetheinyl arm to attach the activated serine or threonine, and a terminal thioesterase domain which assists in the transfer of intermediates from MbtB to ACP1 in MbtD (By similarity). DOMAIN 7 75 Acyl carrier 1., DOMAIN 1062 1132 Acyl carrier 2. PF00501, PF13193, PF00668, PF08415, PF00550, PF00975 Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily., Contains 2 acyl carrier domains. SSF47336

Domain/Family DBs

Gene3D HAMAP PANTHER Pfam PIRSF PRINTS ProDom PROSITE SMART SUPFAM
1.10.1200.10, PF00501, PF13193, PF00668, PF08415, PF00550, PF00975 PS50075, PS00455, PS00012 SSF47336

SSGCID Target Details

SSGCID ID

3D Details

PDB Protein Model Portal

Pathway Details

EC number KEGG KO UniPathway
6.3.2.- Siderophore biosynthesis, mycobactin biosynthesis.

Phylogenetic

HOGENOM KEGG KO OMA OrthoDB