DVU0004 DVU0004 DNA gyrase subunit A

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Desulfovibrio vulgaris Hildenborough

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
DVU0004 DVU0004 gyrA gyrA, DVU0004 DNA gyrase subunit A DNA gyrase subunit A (EC 5.99.1.3) 5262 7832 + 15077118

Regulatory Modules

Residual Expression Plot
bicluster_0018 0.44
bicluster_0029 0.50

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG OrthoDB
Q72G56 2794973 YP_009229.1; 46578421 208931 AAS94488 IPR024946, IPR005743, IPR006691, IPR002205, IPR013758, IPR013757, IPR013760 COG0188 EOG661H5V

Mutations

Line Position Effect Impact Class Percent Frequency Sample Title
HS3 5 565 NON_SYNONYMOUS_CODING MISSENSE 100 TG_HS3 Chr-DVU0004-5565-TG_HS3
HA3 5 565 NON_SYNONYMOUS_CODING MISSENSE 100 EG_HA3_45 Chr-DVU0004-5565-EG_HA3_45
UA3 5 565 NON_SYNONYMOUS_CODING MISSENSE 100 EG_UA3_118 Chr-DVU0004-5565-EG_UA3_118
HA2 5 565 NON_SYNONYMOUS_CODING MISSENSE 100 EP_HA2_09 Chr-DVU0004-5565-EP_HA2_09
HR2 5 565 NON_SYNONYMOUS_CODING MISSENSE 99 HR2.152.05.D02 Chr-DVU0004-5565-HR2.152.05.D02
HA2 5 565 NON_SYNONYMOUS_CODING MISSENSE 100 HA2.152.09.D03 Chr-DVU0004-5565-HA2.152.09.D03
HR2 5 565 NON_SYNONYMOUS_CODING MISSENSE 100 HR2.152.05.D01 Chr-DVU0004-5565-HR2.152.05.D01
HA3 5 565 NON_SYNONYMOUS_CODING MISSENSE 100 EG_HA3_15 Chr-DVU0004-5565-EG_HA3_15
HR1 5 565 NON_SYNONYMOUS_CODING MISSENSE 100 TG_HR1 Chr-DVU0004-5565-TG_HR1
HA2 5 565 NON_SYNONYMOUS_CODING MISSENSE 98 HA2.152.08.D01 Chr-DVU0004-5565-HA2.152.08.D01

Transposon mutants

Title Insert TAG Module
GZ13521 2509 TagModule_0712
GZ9130 2510
DVU0004

Homology

Orthologues Paralogues

Functions

Catalytic Activity COG EC Description Protein families
ATP-dependent breakage, passage and rejoining of double-stranded DNA. {ECO:0000256|HAMAP-Rule:MF_01897, ECO:0000256|SAAS:SAAS00075911}. (L) COG188 | Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit (5.99.1.3) DNA topoisomerase (ATP-hydrolyzing). Topoisomerase GyrA/ParC subunit family

Essentiality

WT.MOLS4 WT.MOLS4_NO3 WT.MOYLS4.1 WT.MOYLS4.2
0.03 0 0 0

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
46578421 YP_009229.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
DVU0004

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