DVU1454 DVU1454 Bifunctional enzyme IspD/IspF | Syntrophy Portal

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Desulfovibrio vulgaris Hildenborough

Summary

	Locus Tag	Symbol	Synonyms	Product	Protein Synonyms	Start	End	Strand	PubMed ID
DVU1454	DVU1454	ispDF	ispDF, ispD, DVU1454	Bifunctional enzyme IspD/IspF	Bifunctional enzyme IspD/IspF [Includes: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (EC 2.7.7.60) (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (MEP cytidylyltransferase) (MCT); 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (MECDP-synthase) (MECPP-synthase) (MECPS) (EC 4.6.1.12)]	1533794	1532607	-	15077118

XReference

Uniprot	NCBI Gene	NCBI Protein	GI Number	MicrobesOnline	EnsemblBacteria	InterPro	EggNOG	OrthoDB
Q72C30	2794820	YP_010673.1;	46579865	206898	AAS95932	IPR001228, IPR026596, IPR018294, IPR003526, IPR020555, IPR029044	COG0245	EOG6J48RZ

Mutations

Line	Position	Effect	Impact	Class	Percent Frequency	Sample	Title

Transposon mutants

Title	Insert	TAG Module
DVU1454

Homology

Orthologues	Paralogues

Functions

Catalytic Activity	COG	EC Description	Protein families
CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol. {ECO:0000255\|HAMAP-Rule:MF_01520}.; 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP. {ECO:0000255\|HAMAP-Rule:MF_01520}.	(I) COG1211 \| 4-diphosphocytidyl-2-methyl-D-erithritol synthase	(2.7.7.60, 4.6.1.12) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase., (2.7.7.60, 4.6.1.12) 2-C-methyl-D-erythritol 2, (2.7.7.60, 4.6.1.12) 4-cyclodiphosphate synthase.	IspD family; IspF family

Essentiality

WT.MOLS4	WT.MOLS4_NO3	WT.MOYLS4.1	WT.MOYLS4.2
1.19	0.02	0.47	0.34

Product Synonyms

Product (LegacyBRC)	Product (RefSeq)

Operon

Refseq

GI Number	Accession	Blast	Conserved Domains
46579865	YP_010673.1	Run

GO Terms

GO:0008685 GO:0050518 GO:0019288 GO:0046872 GO:0016114 -

String Network

Link to STRINGS	STRINGS Network
DVU1454

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