MMP0087 MMP0087 Hydroxymethylglutaryl-coenzyme A reductase:3-hydroxy-3-methylglutaryl Coenzyme A reductase (NCBI)

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Methanococcus maripaludis S2

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
MMP0087 MMP0087 hmgA hmgA, MMP0087 Hydroxymethylglutaryl-coenzyme A reductase:3-hydroxy-3-methylglutaryl Coenzyme A reductase (NCBI) 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) (EC 1.1.1.34) 98987 97761 - 15466049

Regulatory Modules

Residual Expression Plot
mmp-bicluster_0039 0.44
mmp-bicluster_0136 0.41

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG
Q6M131 2761627 NP_987207.1;WP_011170031.1; 45357650 532265 CAF29643 IPR002202, IPR023074, IPR023076, IPR004554, IPR009023, IPR009029 COG1257

Mutations

Transposon mutants

Title Insert TAG Module
MMP0087

Homology

Orthologues Paralogues

Functions

Catalytic Activity COG EC Description Protein families TIGR Roles
(R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH. {ECO:0000256|RuleBase:RU361219}. (I) COG1257 | Hydroxymethylglutaryl-CoA reductase (1.1.1.34) Hydroxymethylglutaryl-CoA reductase (NADPH). HMG-CoA reductase family Central intermediary metabolism:Other

Essentiality

L1.Cm.T1 L1.Cm.T2 L1.cN.T1 L1.cN.T2 L1.T0 L2.Cm.T1 L2.Cm.T2 L2.cN.T1 L2.cN.T2 L2.T0
0 0 0 0 4 0 1 0 0 1

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
45357650 NP_987207.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
MMP0087

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