Methanococcus maripaludis S2 Module 136 Residual: 0.41

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Summary

Residual: 0.41 Score: -11.0678 version: mmp_cmonkey_11_Oct_11

Members

MMP0075 conserved hypothetical protein (NCBI)

Details for MMP0075 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0075

Tuberculist Genomic Region

MMP0917 Diaminopimelate epimerase (NCBI)

Details for MMP0917 - Diaminopimelate epimerase (NCBI)

GO Terms: GO:0009089, GO:0008837

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0917

Tuberculist Genomic Region

MMP0087 Hydroxymethylglutaryl-coenzyme A reductase:3-hydroxy-3-methylglutaryl Coenzyme A reductase (NCBI)

Details for MMP0087 - Hydroxymethylglutaryl-coenzyme A reductase:3-hydroxy-3-methylglutaryl Coenzyme A reductase (NCBI)

GO Terms: GO:0015936, GO:0008299, GO:0016021, GO:0050661, GO:0004420

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0087

Tuberculist Genomic Region

MMP0965 formylmethanofuran dehydrogenase subunit E related protein (NCBI)

Details for MMP0965 - formylmethanofuran dehydrogenase subunit E related protein (NCBI)

GO Terms: GO:0005634, GO:0008270, GO:0018493

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0965

Tuberculist Genomic Region

MMP0088 Glutamyl-tRNA reductase (NCBI)

Details for MMP0088 - Glutamyl-tRNA reductase (NCBI)

GO Terms: GO:0033014, GO:0005737, GO:0050661, GO:0008883, GO:0004764

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0088

Tuberculist Genomic Region

MMP1035

Details for MMP1035 -

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1035

Tuberculist Genomic Region

MMP0164 Sirohydrochlorin cobaltochelatase (NCBI)

Details for MMP0164 - Sirohydrochlorin cobaltochelatase (NCBI)

GO Terms: GO:0009236, GO:0016852, GO:0046872

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0164

Tuberculist Genomic Region

MMP1036 Band 7 protein:Stomatin (NCBI)

Details for MMP1036 - Band 7 protein:Stomatin (NCBI)

GO Terms: GO:0016020

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1036

Tuberculist Genomic Region

MMP0429 Beta-Ig-H3/Fasciclin domain:Protein of unknown function DUF211 (NCBI)

Details for MMP0429 - Beta-Ig-H3/Fasciclin domain:Protein of unknown function DUF211 (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0429

Tuberculist Genomic Region

MMP1175

Details for MMP1175 -

GO Terms: GO:0008171

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1175

Tuberculist Genomic Region

MMP0644 Cation efflux protein (NCBI)

Details for MMP0644 - Cation efflux protein (NCBI)

GO Terms: GO:0006812, GO:0016020, GO:0008324

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0644

Tuberculist Genomic Region

MMP1176 putative iron transport system substrate-binding protein, N-term half (NCBI)

Details for MMP1176 - putative iron transport system substrate-binding protein, N-term half (NCBI)

GO Terms: GO:0006827, GO:0005381

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1176

Tuberculist Genomic Region

MMP0645 malate dehydrogenase, MDHII (NADP+-dependent) (NCBI)

Details for MMP0645 - malate dehydrogenase, MDHII (NADP+-dependent) (NCBI)

GO Terms: GO:0019642, GO:0006100, GO:0006108, GO:0005737, GO:0004459, GO:0030060

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0645

Tuberculist Genomic Region

MMP1177 putative iron transport system substrate-binding protein, C-term half (NCBI)

Details for MMP1177 - putative iron transport system substrate-binding protein, C-term half (NCBI)

GO Terms: GO:0006827, GO:0005381

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1177

Tuberculist Genomic Region

MMP0646 hypothetical protein (NCBI)

Details for MMP0646 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0646

Tuberculist Genomic Region

MMP1178 iron transport Periplasmic binding protein (NCBI)

Details for MMP1178 - iron transport Periplasmic binding protein (NCBI)

GO Terms: GO:0006827, GO:0005381

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1178

Tuberculist Genomic Region

MMP0874 SAM (and some other nucleotide) binding motif (NCBI)

Details for MMP0874 - SAM (and some other nucleotide) binding motif (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0874

Tuberculist Genomic Region

MMP1181 iron transport system binding protein (NCBI)

Details for MMP1181 - iron transport system binding protein (NCBI)

GO Terms: GO:0006827, GO:0005381

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1181

Tuberculist Genomic Region

MMP0875 S layer protein (NCBI)

Details for MMP0875 - S layer protein (NCBI)

GO Terms: GO:0005618

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0875

Tuberculist Genomic Region

MMP1182 Iron(III) dicitrate transport system permease protein (NCBI)

Details for MMP1182 - Iron(III) dicitrate transport system permease protein (NCBI)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1182

Tuberculist Genomic Region

MMP0887 conserved hypothetical protein (NCBI)

Details for MMP0887 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0887

Tuberculist Genomic Region

MMP1183 iron ABC transporter ATPase subunit (NCBI)

Details for MMP1183 - iron ABC transporter ATPase subunit (NCBI)

GO Terms: GO:0005524, GO:0015623

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1183

Tuberculist Genomic Region

MMP0888 putative cobalt transport protein (NCBI)

Details for MMP0888 - putative cobalt transport protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0888

Tuberculist Genomic Region

MMP1646 conserved hypothetical archaeal protein (NCBI)

Details for MMP1646 - conserved hypothetical archaeal protein (NCBI)

GO Terms: GO:0043565

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1646

Tuberculist Genomic Region

MMP0889 Cobalamin (vitamin B12) biosynthesis CbiM protein (NCBI)

Details for MMP0889 - Cobalamin (vitamin B12) biosynthesis CbiM protein (NCBI)

GO Terms: GO:0009236, GO:0016021

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0889

Tuberculist Genomic Region

MMP1699 conserved hypothetical archaeal protein (NCBI)

Details for MMP1699 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1699

Tuberculist Genomic Region

Displaying 1 - 26 of 26

Motifs

Motif 1: e-value: 4700 e-value: 9000

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0033

LysR family member (NCBI)

MMP0629

conserved hypothetical archaeal protein (NCBI)
 up-regulates 0.34

MMP0033

MMP0629

MMP0465

conserved hypothetical archaeal protein (NCBI)
 down-regulates -0.32

MMP0465

MMP0209

Conserved hypothetical protein (NCBI)

MMP1023

Transcriptional regulator, TetR Family Member (NCBI)
 up-regulates 0.29

MMP0209

MMP1023

MMP0791

Transcriptional regulator, TetR Family Member (NCBI)
 down-regulates -0.14

MMP0791

GO Enrichment

Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0050661 NADP binding 5 0.05 2 0.0009
MF GO:0050662 coenzyme binding 28 0.29 2 0.0310
MF GO:0048037 cofactor binding 32 0.33 2 0.0398

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