MMP0697 MMP0697 Leucyl-tRNA synthetase (NCBI)

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Methanococcus maripaludis S2

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Summary

Locus Tag Symbol Synonyms Product Protein Synonyms Start End Strand PubMed ID
MMP0697 MMP0697 leuS leuS, MMP0697 Leucyl-tRNA synthetase (NCBI) Leucine--tRNA ligase (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) 686587 689454 + 15466049

Regulatory Modules

Residual Expression Plot
mmp-bicluster_0143 0.30

XReference

Uniprot NCBI Gene NCBI Protein GI Number MicrobesOnline EnsemblBacteria InterPro EggNOG
Q6LZD2 2761186 NP_987817.1; 45358260 532890 CAF30253 IPR001412, IPR002300, IPR020791, IPR004493, IPR013155, IPR015413, IPR014729, IPR009080, IPR009008 COG0495

Mutations

Line Position Effect Impact Class Percent Frequency Sample Title
HR2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 EP_HR2_01 BX950229-MMP0697-687745-EP_HR2_01
HR2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 EP_HR2_05 BX950229-MMP0697-687745-EP_HR2_05
HR2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 EP_HR2_10 BX950229-MMP0697-687745-EP_HR2_10
UE3 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 EP_UE3_10 BX950229-MMP0697-687745-EP_UE3_10
UE3 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 EP_UE3_09 BX950229-MMP0697-687745-EP_UE3_09
UE3 687 745 NON_SYNONYMOUS_CODING MISSENSE 99 EP_UE3_03 BX950229-MMP0697-687745-EP_UE3_03
HA2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 HA2.152.08.M01 BX950229-MMP0697-687745-HA2.152.08.M01
HA2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 HA2.152.01.M01 BX950229-MMP0697-687745-HA2.152.01.M01
HR2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 HR2.152.01.M02 BX950229-MMP0697-687745-HR2.152.01.M02
HR2 687 745 NON_SYNONYMOUS_CODING MISSENSE 100 HR2.152.05.M01 BX950229-MMP0697-687745-HR2.152.05.M01

Transposon mutants

Title Insert TAG Module
MMP0697

Homology

Orthologues Paralogues

Functions

Catalytic Activity COG EC Description Protein families TIGR Roles
ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu). {ECO:0000255|HAMAP-Rule:MF_00049}. (J) COG495 | Leucyl-tRNA synthetase (6.1.1.4) Leucine--tRNA ligase. Class-I aminoacyl-tRNA synthetase family Protein synthesis:tRNA aminoacylation

Essentiality

L1.Cm.T1 L1.Cm.T2 L1.cN.T1 L1.cN.T2 L1.T0 L2.Cm.T1 L2.Cm.T2 L2.cN.T1 L2.cN.T2 L2.T0
0 0 1 0 11 1 1 0 0 3

Product Synonyms

Product (LegacyBRC) Product (RefSeq)

Operon

Refseq

GI Number Accession Blast Conserved Domains
45358260 NP_987817.1 Run

GO Terms

String Network

Link to STRINGS STRINGS Network
MMP0697

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