Methanococcus maripaludis S2 Module 143 Residual: 0.30

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Summary

Residual: 0.30 Score: -15.6091 version: mmp_cmonkey_11_Oct_11

Members

MMP0007 Conserved hypothetical protein (NCBI)

Details for MMP0007 - Conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0007

Tuberculist Genomic Region

MMP1081 putative LPS biosynthesis protein WbpG (NCBI)

Details for MMP1081 - putative LPS biosynthesis protein WbpG (NCBI)

GO Terms: GO:0009435, GO:0008033, GO:0005737, GO:0005524, GO:0004808, GO:0003952

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1081

Tuberculist Genomic Region

MMP0145 Hypoxanthine (guanine) phosphoribosyltransferase (NCBI)

Details for MMP0145 - Hypoxanthine (guanine) phosphoribosyltransferase (NCBI)

GO Terms: GO:0006168, GO:0009116, GO:0003999

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0145

Tuberculist Genomic Region

MMP1082 Similar to bacterial imidazoleglycerol-phosphate synthase, amidotransferase subunit (NCBI)

Details for MMP1082 - Similar to bacterial imidazoleglycerol-phosphate synthase, amidotransferase subunit (NCBI)

GO Terms: GO:0006541, GO:0000105, GO:0005737, GO:0016763

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1082

Tuberculist Genomic Region

MMP0153 2-oxosuberate synthase, first step (NCBI)

Details for MMP0153 - 2-oxosuberate synthase, first step (NCBI)

GO Terms: GO:0019752, GO:0003852, GO:0046912

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0153

Tuberculist Genomic Region

MMP1083 Similar to bacterial imidazoleglycerol-phosphate synthase, cyclase subunit (NCBI)

Details for MMP1083 - Similar to bacterial imidazoleglycerol-phosphate synthase, cyclase subunit (NCBI)

GO Terms: GO:0000105, GO:0006222, GO:0004152, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1083

Tuberculist Genomic Region

MMP0178 Phosphoribosylformylglycinamidine synthase I (NCBI)

Details for MMP0178 - Phosphoribosylformylglycinamidine synthase I (NCBI)

GO Terms: GO:0006189, GO:0005737, GO:0004642

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0178

Tuberculist Genomic Region

MMP1122 GTP1/OBG family:ATP/GTP-binding site motif A (P-loop):TGS domain (NCBI)

Details for MMP1122 - GTP1/OBG family:ATP/GTP-binding site motif A (P-loop):TGS domain (NCBI)

GO Terms: GO:0015684, GO:0009276, GO:0016021, GO:0005622, GO:0015093, GO:0005525

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1122

Tuberculist Genomic Region

MMP0179 Phosphoribosylformylglycinamidine synthase II (NCBI)

Details for MMP0179 - Phosphoribosylformylglycinamidine synthase II (NCBI)

GO Terms: GO:0004642

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0179

Tuberculist Genomic Region

MMP1198 nitrate/sulfonate/bicarbonate ABC transporter ATPase subunit (NCBI)

Details for MMP1198 - nitrate/sulfonate/bicarbonate ABC transporter ATPase subunit (NCBI)

GO Terms: GO:0005524, GO:0016887

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1198

Tuberculist Genomic Region

MMP0187 thiamine biosynthesis protein, putative (NCBI)

Details for MMP0187 - thiamine biosynthesis protein, putative (NCBI)

GO Terms: GO:0009228, GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0187

Tuberculist Genomic Region

MMP1496 Phenylalanyl-tRNA synthetase alpha subunit (NCBI)

Details for MMP1496 - Phenylalanyl-tRNA synthetase alpha subunit (NCBI)

GO Terms: GO:0006432, GO:0009328, GO:0005524, GO:0004826

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1496

Tuberculist Genomic Region

MMP0264 Mechanosensitive (MS) ion channel (NCBI)

Details for MMP0264 - Mechanosensitive (MS) ion channel (NCBI)

GO Terms: GO:0016020

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0264

Tuberculist Genomic Region

MMP1592 Tryptophanyl-tRNA synthetase (NCBI)

Details for MMP1592 - Tryptophanyl-tRNA synthetase (NCBI)

GO Terms: GO:0006436, GO:0005737, GO:0005524, GO:0004830

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1592

Tuberculist Genomic Region

MMP0540 Phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI)

Details for MMP0540 - Phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI)

GO Terms: GO:0006164, GO:0004639, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0540

Tuberculist Genomic Region

MMP1594 conserved hypothetical protein (NCBI)

Details for MMP1594 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1594

Tuberculist Genomic Region

MMP0606 23 S ribosomal RNA methyltransferase related (NCBI)

Details for MMP0606 - 23 S ribosomal RNA methyltransferase related (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0606

Tuberculist Genomic Region

MMP1681 Phosphoadenosine phosphosulfate reductase (NCBI)

Details for MMP1681 - Phosphoadenosine phosphosulfate reductase (NCBI)

GO Terms: GO:0008152, GO:0016740

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1681

Tuberculist Genomic Region

MMP0607 Transcriptional repressor of nif and glnA operons (NCBI)

Details for MMP0607 - Transcriptional repressor of nif and glnA operons (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0607

Tuberculist Genomic Region

MMP0418 Carbohydrate kinase, PfkB (NCBI)

Details for MMP0418 - Carbohydrate kinase, PfkB (NCBI)

GO Terms: GO:0006014, GO:0004747

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0418

Tuberculist Genomic Region

MMP0697 Leucyl-tRNA synthetase (NCBI)

Details for MMP0697 - Leucyl-tRNA synthetase (NCBI)

GO Terms: GO:0006429, GO:0005737, GO:0004823, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0697

Tuberculist Genomic Region

MMP1085 conserved hypothetical protein (NCBI)

Details for MMP1085 - conserved hypothetical protein (NCBI)

GO Terms: GO:0008152, GO:0008168

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1085

Tuberculist Genomic Region

MMP0698 conserved hypothetical protein (NCBI)

Details for MMP0698 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0698

Tuberculist Genomic Region

MMP0880 2-oxosuberate synthase, last step (NCBI)

Details for MMP0880 - 2-oxosuberate synthase, last step (NCBI)

GO Terms: GO:0009098, GO:0003862, GO:0051287

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0880

Tuberculist Genomic Region

MMP0879 Seryl-tRNA synthetase (NCBI)

Details for MMP0879 - Seryl-tRNA synthetase (NCBI)

GO Terms: GO:0006434, GO:0005737, GO:0005524, GO:0004828

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0879

Tuberculist Genomic Region

MMP1146 Amidophosphoribosyltransferase (NCBI)

Details for MMP1146 - Amidophosphoribosyltransferase (NCBI)

GO Terms: GO:0009113, GO:0009116, GO:0004044

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1146

Tuberculist Genomic Region

MMP1063 2-isopropylmalate synthase (NCBI)

Details for MMP1063 - 2-isopropylmalate synthase (NCBI)

GO Terms: GO:0019752, GO:0003852

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1063

Tuberculist Genomic Region

Displaying 1 - 27 of 27

Motifs

Motif 1: e-value: 2400 e-value: 4700

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences
[field_regulator_taxonomy_regulat_1]

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0006164 purine nucleotide biosynthetic process 16 0.67 5 0.0001
BP GO:0009127 purine nucleoside monophosphate biosynth... 16 0.67 5 0.0001
BP GO:0009152 purine ribonucleotide biosynthetic proce... 16 0.67 5 0.0001
BP GO:0009168 purine ribonucleoside monophosphate bios... 16 0.67 5 0.0001
BP GO:0006163 purine nucleotide metabolic process 17 0.71 5 0.0001
BP GO:0009126 purine nucleoside monophosphate metaboli... 17 0.71 5 0.0001
BP GO:0009150 purine ribonucleotide metabolic process 17 0.71 5 0.0001
BP GO:0009167 purine ribonucleoside monophosphate meta... 17 0.71 5 0.0001
BP GO:0072522 purine-containing compound biosynthetic ... 17 0.71 5 0.0001
BP GO:0072521 purine-containing compound metabolic pro... 19 0.79 5 0.0003
BP GO:0006189 'de novo' IMP biosynthetic process 11 0.46 4 0.0004
BP GO:0009124 nucleoside monophosphate biosynthetic pr... 23 0.96 5 0.0007
BP GO:0009156 ribonucleoside monophosphate biosyntheti... 23 0.96 5 0.0007
BP GO:0009123 nucleoside monophosphate metabolic proce... 24 1.00 5 0.0009
BP GO:0009161 ribonucleoside monophosphate metabolic p... 24 1.00 5 0.0009
BP GO:0009260 ribonucleotide biosynthetic process 25 1.04 5 0.0011
BP GO:0046390 ribose phosphate biosynthetic process 25 1.04 5 0.0011
BP GO:0009259 ribonucleotide metabolic process 26 1.08 5 0.0013
BP GO:0019693 ribose phosphate metabolic process 27 1.12 5 0.0016
BP GO:1901137 carbohydrate derivative biosynthetic pro... 27 1.12 5 0.0016
BP GO:0009165 nucleotide biosynthetic process 28 1.17 5 0.0019
BP GO:1901293 nucleoside phosphate biosynthetic proces... 28 1.17 5 0.0019
BP GO:0006753 nucleoside phosphate metabolic process 31 1.29 5 0.0032
BP GO:0009117 nucleotide metabolic process 31 1.29 5 0.0032
BP GO:0044710 single-organism metabolic process 99 4.12 8 0.0043
BP GO:1901135 carbohydrate derivative metabolic proces... 34 1.42 5 0.0050
BP GO:0034654 nucleobase-containing compound biosynthe... 35 1.46 5 0.0057
BP GO:0090407 organophosphate biosynthetic process 36 1.50 5 0.0066
BP GO:0055086 nucleobase-containing small molecule met... 37 1.54 5 0.0075
BP GO:0019637 organophosphate metabolic process 41 1.71 5 0.0121
BP GO:0006796 phosphate-containing compound metabolic ... 43 1.79 5 0.0150
BP GO:0019438 aromatic compound biosynthetic process 63 2.62 6 0.0161
BP GO:0006793 phosphorus metabolic process 44 1.83 5 0.0166
BP GO:0044281 small molecule metabolic process 87 3.62 7 0.0170
BP GO:0044699 single-organism process 117 4.88 8 0.0173
BP GO:0018130 heterocycle biosynthetic process 71 2.96 6 0.0307
BP GO:0044711 single-organism biosynthetic process 74 3.08 6 0.0381
BP GO:1901362 organic cyclic compound biosynthetic pro... 74 3.08 6 0.0381
BP GO:0006139 nucleobase-containing compound metabolic... 54 2.25 5 0.0411
BP GO:0044238 primary metabolic process 101 4.21 7 0.0447
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0035639 purine ribonucleoside triphosphate bindi... 169 2.40 6 0.0170
MF GO:0001883 purine nucleoside binding 171 2.43 6 0.0180
MF GO:0017076 purine nucleotide binding 171 2.43 6 0.0180
MF GO:0032549 ribonucleoside binding 171 2.43 6 0.0180
MF GO:0032550 purine ribonucleoside binding 171 2.43 6 0.0180
MF GO:0032555 purine ribonucleotide binding 171 2.43 6 0.0180
MF GO:0001882 nucleoside binding 172 2.45 6 0.0190
MF GO:0032553 ribonucleotide binding 181 2.58 6 0.0240
MF GO:0097367 carbohydrate derivative binding 182 2.59 6 0.0250
MF GO:0043168 anion binding 196 2.79 6 0.0360
MF GO:0000166 nucleotide binding 200 2.85 6 0.0390
MF GO:1901265 nucleoside phosphate binding 200 2.85 6 0.0390
MF GO:0005524 ATP binding 147 2.09 5 0.0400
MF GO:0030554 adenyl nucleotide binding 149 2.12 5 0.0430
MF GO:0032559 adenyl ribonucleotide binding 149 2.12 5 0.0430
MF GO:0036094 small molecule binding 210 2.99 6 0.0490

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