Methanococcus maripaludis S2 Module 70 Residual: 0.49

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Summary

Residual: 0.49 Score: -11.3358 version: mmp_cmonkey_11_Oct_11

Members

MMP0183 3,4-dihydroxy-2-butanone 4-phosphate synthase (NCBI)

Details for MMP0183 - 3,4-dihydroxy-2-butanone 4-phosphate synthase (NCBI)

GO Terms: GO:0009231, GO:0008686

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0183

Tuberculist Genomic Region

MMP0448 hypothetical protein (NCBI)

Details for MMP0448 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0448

Tuberculist Genomic Region

MMP0220 Sodium/proline symporter-related (NCBI)

Details for MMP0220 - Sodium/proline symporter-related (NCBI)

GO Terms: GO:0006810, GO:0016020, GO:0005215

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0220

Tuberculist Genomic Region

MMP0449 ferredoxin (NCBI)

Details for MMP0449 - ferredoxin (NCBI)

GO Terms: GO:0006118, GO:0009236, GO:0051536, GO:0009055, GO:0042242

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0449

Tuberculist Genomic Region

MMP0382 RNase L inhibitor (NCBI)

Details for MMP0382 - RNase L inhibitor (NCBI)

GO Terms: GO:0006118, GO:0005524, GO:0009055, GO:0016887, GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0382

Tuberculist Genomic Region

MMP0450 ferredoxin (NCBI)

Details for MMP0450 - ferredoxin (NCBI)

GO Terms: GO:0006118, GO:0009236, GO:0051536, GO:0009055, GO:0042242

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0450

Tuberculist Genomic Region

MMP0385 uridylate kinase (NCBI)

Details for MMP0385 - uridylate kinase (NCBI)

GO Terms: GO:0006221, GO:0008652, GO:0009041

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0385

Tuberculist Genomic Region

MMP0451 conserved hypothetical protein (NCBI)

Details for MMP0451 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0451

Tuberculist Genomic Region

MMP0397 Alanyl-tRNA synthetase (NCBI)

Details for MMP0397 - Alanyl-tRNA synthetase (NCBI)

GO Terms: GO:0006419, GO:0005737, GO:0003676, GO:0004813, GO:0016787, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0397

Tuberculist Genomic Region

MMP0498 putative uncharacterized membrane protein, ortholog YYAS B.subtilis (NCBI)

Details for MMP0498 - putative uncharacterized membrane protein, ortholog YYAS B.subtilis (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0498

Tuberculist Genomic Region

MMP0399 Peptidase family M48 (NCBI)

Details for MMP0399 - Peptidase family M48 (NCBI)

GO Terms: GO:0006508, GO:0016020, GO:0004222

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0399

Tuberculist Genomic Region

MMP0618 conserved hypothetical protein (NCBI)

Details for MMP0618 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0618

Tuberculist Genomic Region

MMP0400 Conserved hypothetical protein (NCBI)

Details for MMP0400 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0008152, GO:0016597

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0400

Tuberculist Genomic Region

MMP0619 Putative DNA binding protein (NCBI)

Details for MMP0619 - Putative DNA binding protein (NCBI)

GO Terms: GO:0006352, GO:0006355, GO:0003700, GO:0016987

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0619

Tuberculist Genomic Region

MMP0500 Iron-sulfur flavoprotein-related (NCBI)

Details for MMP0500 - Iron-sulfur flavoprotein-related (NCBI)

GO Terms: GO:0016491, GO:0050662

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0500

Tuberculist Genomic Region

MMP0620 methyl coenzyme M reductase, component A2 (NCBI)

Details for MMP0620 - methyl coenzyme M reductase, component A2 (NCBI)

GO Terms: GO:0005524, GO:0016887

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0620

Tuberculist Genomic Region

MMP0899 ATP/GTP-binding site motif A (P-loop) (NCBI)

Details for MMP0899 - ATP/GTP-binding site motif A (P-loop) (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0899

Tuberculist Genomic Region

MMP0816 bacterial seryl-tRNA synthetase related (NCBI)

Details for MMP0816 - bacterial seryl-tRNA synthetase related (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0816

Tuberculist Genomic Region

MMP0900 Rhodanese-like (NCBI)

Details for MMP0900 - Rhodanese-like (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0900

Tuberculist Genomic Region

MMP0898 Cellulose-binding, bacterial type (NCBI)

Details for MMP0898 - Cellulose-binding, bacterial type (NCBI)

GO Terms: GO:0005975, GO:0004553, GO:0030246

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0898

Tuberculist Genomic Region

MMP0954 hypothetical protein (NCBI)

Details for MMP0954 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0954

Tuberculist Genomic Region

MMP0904 AIR synthase related protein:Selenide water dikinase (NCBI)

Details for MMP0904 - AIR synthase related protein:Selenide water dikinase (NCBI)

GO Terms: GO:0005524, GO:0004756

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0904

Tuberculist Genomic Region

MMP1137 Lrp-Like Transcriptional regulatory proteins, AsnC family (NCBI)

Details for MMP1137 - Lrp-Like Transcriptional regulatory proteins, AsnC family (NCBI)

GO Terms: GO:0006355, GO:0005622, GO:0005506, GO:0003700, GO:0043565

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1137

Tuberculist Genomic Region

MMP0949 tRNA nucleotidyltransferase (NCBI)

Details for MMP0949 - tRNA nucleotidyltransferase (NCBI)

GO Terms: GO:0001680, GO:0003919, GO:0016437, GO:0003723, GO:0004810

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0949

Tuberculist Genomic Region

MMP1138 Hydroxyethylthiazole kinase family (NCBI)

Details for MMP1138 - Hydroxyethylthiazole kinase family (NCBI)

GO Terms: GO:0009228, GO:0004417

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1138

Tuberculist Genomic Region

MMP0966 uroporphyrin-III C-methyltransferase (NCBI)

Details for MMP0966 - uroporphyrin-III C-methyltransferase (NCBI)

GO Terms: GO:0006779, GO:0004851

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0966

Tuberculist Genomic Region

MMP0270 conserved archaeal protein (NCBI)

Details for MMP0270 - conserved archaeal protein (NCBI)

GO Terms: GO:0051536

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0270

Tuberculist Genomic Region

MMP1022 conserved hypothetical protein (NCBI)

Details for MMP1022 - conserved hypothetical protein (NCBI)

GO Terms: GO:0016021, GO:0008158

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1022

Tuberculist Genomic Region

MMP0272 ABC transporter ATPase subunit (NCBI)

Details for MMP0272 - ABC transporter ATPase subunit (NCBI)

GO Terms: GO:0005524, GO:0016887

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0272

Tuberculist Genomic Region

MMP1089 Polysaccharide biosynthesis protein (NCBI)

Details for MMP1089 - Polysaccharide biosynthesis protein (NCBI)

GO Terms: GO:0000271, GO:0006855, GO:0016020, GO:0015238, GO:0015297

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1089

Tuberculist Genomic Region

MMP0273 (2R)-phospho-3-sulfolactate synthase (NCBI)

Details for MMP0273 - (2R)-phospho-3-sulfolactate synthase (NCBI)

GO Terms: GO:0019295, GO:0043817

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0273

Tuberculist Genomic Region

MMP1093 4'-phosphopantetheine adenylyltransferase (NCBI)

Details for MMP1093 - 4'-phosphopantetheine adenylyltransferase (NCBI)

GO Terms: GO:0009058, GO:0004595, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1093

Tuberculist Genomic Region

MMP0274 hydrogenase expression/formation protein (NCBI)

Details for MMP0274 - hydrogenase expression/formation protein (NCBI)

GO Terms: GO:0003824

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0274

Tuberculist Genomic Region

MMP0398 Conserved hypothetical archaeal protein (NCBI)

Details for MMP0398 - Conserved hypothetical archaeal protein (NCBI)

GO Terms: GO:0016310, GO:0005524, GO:0016301

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0398

Tuberculist Genomic Region

MMP0345 Conserved hypothetical protein (NCBI)

Details for MMP0345 - Conserved hypothetical protein (NCBI)

GO Terms: GO:0006810

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0345

Tuberculist Genomic Region

MMP1129 Peptidyl-prolyl cis-trans isomerase, cyclophilin type (NCBI)

Details for MMP1129 - Peptidyl-prolyl cis-trans isomerase, cyclophilin type (NCBI)

GO Terms: GO:0006457, GO:0030051, GO:0042027, GO:0003755, GO:0004600

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1129

Tuberculist Genomic Region

MMP0371 conserved hypothetical protein (NCBI)

Details for MMP0371 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0371

Tuberculist Genomic Region

MMP1139 Thiamine monophosphate synthase (NCBI)

Details for MMP1139 - Thiamine monophosphate synthase (NCBI)

GO Terms: GO:0009228, GO:0004789

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1139

Tuberculist Genomic Region

MMP0402 Conserved hypothetical Archael protein (NCBI)

Details for MMP0402 - Conserved hypothetical Archael protein (NCBI)

GO Terms: GO:0006355, GO:0005622, GO:0003700

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0402

Tuberculist Genomic Region

Displaying 1 - 39 of 39

Motifs

Motif 1: e-value: 150 e-value: 4000

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP0033

LysR family member (NCBI)

H2

 up-regulates 0.52

MMP0033

H2

MMP0568

transcriptional regulator related protein (NCBI)

H2

 up-regulates 0.39

MMP0568

H2

MMP0465

conserved hypothetical archaeal protein (NCBI)

Formate

 down-regulates -0.17

MMP0465

Formate

GO Enrichment

Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0005524 ATP binding 147 3.61 8 0.0160
MF GO:0030554 adenyl nucleotide binding 149 3.66 8 0.0180
MF GO:0032559 adenyl ribonucleotide binding 149 3.66 8 0.0180
MF GO:0043167 ion binding 220 5.41 10 0.0210
MF GO:0043168 anion binding 196 4.82 9 0.0300
MF GO:0035639 purine ribonucleoside triphosphate bindi... 169 4.15 8 0.0360
MF GO:0001883 purine nucleoside binding 171 4.20 8 0.0390
MF GO:0017076 purine nucleotide binding 171 4.20 8 0.0390
MF GO:0032549 ribonucleoside binding 171 4.20 8 0.0390
MF GO:0032550 purine ribonucleoside binding 171 4.20 8 0.0390
MF GO:0032555 purine ribonucleotide binding 171 4.20 8 0.0390
MF GO:0001882 nucleoside binding 172 4.23 8 0.0400
MF GO:0036094 small molecule binding 210 5.16 9 0.0460

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