Methanococcus maripaludis S2 Module 111 Residual: 0.30

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Summary

Residual: 0.30 Score: -16.0231 version: mmp_cmonkey_11_Oct_11

Members

MMP0564 conserved hypothetical archaeal protein (NCBI)

Details for MMP0564 - conserved hypothetical archaeal protein (NCBI)

GO Terms: GO:0003824, GO:0005524

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0564

Tuberculist Genomic Region

MMP0079 Orotate phosphoribosyltransferase related protein (NCBI)

Details for MMP0079 - Orotate phosphoribosyltransferase related protein (NCBI)

GO Terms: GO:0009116, GO:0004588

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0079

Tuberculist Genomic Region

MMP0706 NAD binding site:UDP-glucose/GDP-mannose dehydrogenase (NCBI)

Details for MMP0706 - NAD binding site:UDP-glucose/GDP-mannose dehydrogenase (NCBI)

GO Terms: GO:0006118, GO:0016616, GO:0051287

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0706

Tuberculist Genomic Region

MMP0325 Glyceraldehyde 3-phosphate dehydrogenase (NCBI)

Details for MMP0325 - Glyceraldehyde 3-phosphate dehydrogenase (NCBI)

GO Terms: GO:0006096, GO:0005737, GO:0004365, GO:0050661, GO:0051287, GO:0043891

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0325

Tuberculist Genomic Region

MMP0881 hypothetical protein (NCBI)

Details for MMP0881 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0881

Tuberculist Genomic Region

MMP0561 Carboxymuconolactone decarboxylase:Alkylhydroperoxidase AhpD core domain (NCBI)

Details for MMP0561 - Carboxymuconolactone decarboxylase:Alkylhydroperoxidase AhpD core domain (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0561

Tuberculist Genomic Region

MMP0942 conserved hypothetical protein (NCBI)

Details for MMP0942 - conserved hypothetical protein (NCBI)

GO Terms: GO:0016021

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0942

Tuberculist Genomic Region

MMP0602 Orotidine-5'-phosphate decarboxylase (NCBI)

Details for MMP0602 - Orotidine-5'-phosphate decarboxylase (NCBI)

GO Terms: GO:0006207, GO:0004590

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0602

Tuberculist Genomic Region

MMP1107 Signal recognition particle protein SRP19 (NCBI)

Details for MMP1107 - Signal recognition particle protein SRP19 (NCBI)

GO Terms: GO:0006614, GO:0048500, GO:0008312

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1107

Tuberculist Genomic Region

MMP0943 glycerol-3-phosphate cytidyltransferase (NCBI)

Details for MMP0943 - glycerol-3-phosphate cytidyltransferase (NCBI)

GO Terms: GO:0009058, GO:0016779

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0943

Tuberculist Genomic Region

MMP1109 conserved hypothetical protein (NCBI)

Details for MMP1109 - conserved hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1109

Tuberculist Genomic Region

MMP1345 undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase) (NCBI)

Details for MMP1345 - undecaprenyl pyrophospahte synthetase related protein (Di-trans-poly-cis-decaprenylcistransferase) (NCBI)

GO Terms: GO:0008152, GO:0008834

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1345

Tuberculist Genomic Region

MMP1112 conserved hypothetical archaeal protein (NCBI)

Details for MMP1112 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1112

Tuberculist Genomic Region

MMP1470 Prefoldin alpha subunit (GimC alpha subunit). (NCBI)

Details for MMP1470 - Prefoldin alpha subunit (GimC alpha subunit). (NCBI)

GO Terms: GO:0006457, GO:0016272, GO:0051082

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1470

Tuberculist Genomic Region

MMP1344 hypothetical protein (NCBI)

Details for MMP1344 - hypothetical protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1344

Tuberculist Genomic Region

MMP0131 Pyridoxal phosphate-dependent amino acid decarboxylase (NCBI)

Details for MMP0131 - Pyridoxal phosphate-dependent amino acid decarboxylase (NCBI)

GO Terms: GO:0009058, GO:0019752, GO:0030170, GO:0016769, GO:0016831

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0131

Tuberculist Genomic Region

MMP1659 Aspartate carbamoyltransferase; catalytic subunit (NCBI)

Details for MMP1659 - Aspartate carbamoyltransferase; catalytic subunit (NCBI)

GO Terms: GO:0006207, GO:0006520, GO:0016597, GO:0004070

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1659

Tuberculist Genomic Region

MMP1491 Chlorohydrolase (NCBI)

Details for MMP1491 - Chlorohydrolase (NCBI)

GO Terms: GO:0016810

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1491

Tuberculist Genomic Region

MMP1722 Imidazoleglycerol-phosphate synthase, cyclase subunit (NCBI)

Details for MMP1722 - Imidazoleglycerol-phosphate synthase, cyclase subunit (NCBI)

GO Terms: GO:0000105, GO:0005737, GO:0009382, GO:0000107

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1722

Tuberculist Genomic Region

MMP1521 conserved hypothetical archaeal protein (NCBI)

Details for MMP1521 - conserved hypothetical archaeal protein (NCBI)

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP1521

Tuberculist Genomic Region

MMP0078 conserved hypothetical protein (NCBI)

Details for MMP0078 - conserved hypothetical protein (NCBI)

GO Terms: GO:0006118, GO:0051536, GO:0009055, GO:0016491, GO:0020037

PATRIC Pathways: NA

Essentiality: Griffin Essential: NA | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: MMP0078

Tuberculist Genomic Region

Displaying 1 - 21 of 21

Motifs

Motif 1: e-value: 77 e-value: 290

Module Plots

Regulation

Regulator Interaction Influence Weight Other Influences

MMP1447

Cro repressor family Helix-turn-helix motif containing protein (NCBI)
 down-regulates -0.35

MMP1447

GO Enrichment

Category: BP
Category GO ID GO Term Annotated Expected Significant p-value
BP GO:0009116 nucleoside metabolic process 16 0.33 3 0.0018
BP GO:1901657 glycosyl compound metabolic process 16 0.33 3 0.0018
BP GO:0006222 UMP biosynthetic process 6 0.12 2 0.0048
BP GO:0009129 pyrimidine nucleoside monophosphate meta... 6 0.12 2 0.0048
BP GO:0009130 pyrimidine nucleoside monophosphate bios... 6 0.12 2 0.0048
BP GO:0009173 pyrimidine ribonucleoside monophosphate ... 6 0.12 2 0.0048
BP GO:0009174 pyrimidine ribonucleoside monophosphate ... 6 0.12 2 0.0048
BP GO:0044205 'de novo' UMP biosynthetic process 6 0.12 2 0.0048
BP GO:0046049 UMP metabolic process 6 0.12 2 0.0048
BP GO:0006213 pyrimidine nucleoside metabolic process 8 0.17 2 0.0088
BP GO:0006220 pyrimidine nucleotide metabolic process 8 0.17 2 0.0088
BP GO:0006221 pyrimidine nucleotide biosynthetic proce... 8 0.17 2 0.0088
BP GO:0009218 pyrimidine ribonucleotide metabolic proc... 8 0.17 2 0.0088
BP GO:0009220 pyrimidine ribonucleotide biosynthetic p... 8 0.17 2 0.0088
BP GO:0046131 pyrimidine ribonucleoside metabolic proc... 8 0.17 2 0.0088
BP GO:0046132 pyrimidine ribonucleoside biosynthetic p... 8 0.17 2 0.0088
BP GO:0046134 pyrimidine nucleoside biosynthetic proce... 8 0.17 2 0.0088
BP GO:1901135 carbohydrate derivative metabolic proces... 34 0.71 3 0.0181
BP GO:0055086 nucleobase-containing small molecule met... 37 0.77 3 0.0232
BP GO:0009163 nucleoside biosynthetic process 13 0.27 2 0.0236
BP GO:0042455 ribonucleoside biosynthetic process 13 0.27 2 0.0236
BP GO:0072527 pyrimidine-containing compound metabolic... 13 0.27 2 0.0236
BP GO:0072528 pyrimidine-containing compound biosynthe... 13 0.27 2 0.0236
BP GO:1901659 glycosyl compound biosynthetic process 13 0.27 2 0.0236
BP GO:0009119 ribonucleoside metabolic process 15 0.31 2 0.0313
Category: MF
Category GO ID GO Term Annotated Expected Significant p-value
MF GO:0051287 NAD binding 8 0.09 2 0.0033
MF GO:0016209 antioxidant activity 3 0.03 1 0.0346
MF GO:0016684 oxidoreductase activity, acting on perox... 3 0.03 1 0.0346
MF GO:0046906 tetrapyrrole binding 3 0.03 1 0.0346
MF GO:0050662 coenzyme binding 28 0.33 2 0.0389
MF GO:0048037 cofactor binding 32 0.37 2 0.0499

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