42704 (LEU2) IPMI
Thalassiosira pseudonana

Genome Browser

Summary

Chromosome Product Transcript Start End Strand Short Name
42704 chr_17 (LEU2) IPMI 575147 578028 + IPMI

Synonyms

NCBI ID Ensembl Genomes exon ID
7442154 Thaps42704.1, Thaps42704.3, Thaps42704.2

Hierarchical Clustering

Expression Profile Conditional Changes Cluster Dendrogram
Thaps_hclust_0291

Motif-Guided Biclusters

Normalized Mean Residue
Thaps_bicluster_0279
 0.39

Most Highly Correlated Transcripts

22293

PLN00178
0.9252

bd1828

(bd1828) NA
0.8886

36525

PRK09427
0.8844

22770

PLN02908
0.8765

268062

PRK14293
0.8638

4524

DHQS
0.8629

9247

hypothetical protein
0.8623

264365

PRK08661
0.8606

38964

Chorismate_synthase
0.8596

35049

PRK07411
0.8396

Conserved Domains

Name CD Accession Definition Superfamily Bitscore E-Value From - To Hit Type PSSM ID
IPMI 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-... cl00285 573.367 0 70 - 495 specific 153133
Aconitase superfamily Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and... - 573.367 0 70 - 495 superfamily 260326
IPMI_Swivel Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins... cl00215 131.172 9.70E-36 583 - 723 specific 238809
Aconitase_swivel superfamily Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of... - 131.172 9.70E-36 583 - 723 superfamily 260268
PRK07229 aconitate hydratase; Validated - 228.107 1.88E-64 46 - 750 multi-dom 235974

Homologs in Other Species

T. pseudonana P. tricornutum P. tricornutum DiatomCyc F. cylindrus Pseudo-nitzschia multiseries E. huxleyi C. reinhardtii A. thaliana P. sojae
263961 PHATRDRAFT_24772 PHATRDRAFT_24772 204229 206349 421960 Cre01.g004500.t1.2 AT4G13430.1 562967

KEGG

KEGG description KEGG Pathway
Biosynthesis of secondary metabolites map01110

GO Terms

GO:0008152 GO:0016836 GO:0016829 GO:0003861 GO:0009098 GO:0009316 -

GO:0008152

metabolic process

Details: 
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO Category: 
BP

GO:0016836

hydro-lyase activity

Details: 
Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
GO Category: 
MF

GO:0016829

lyase activity

Details: 
Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
GO Category: 
MF

GO:0003861

3-isopropylmalate dehydratase activity

Details: 
Catalysis of the reaction: 3-isopropylmalate = 2-isopropylmaleate + H2O.
GO Category: 
MF

GO:0009098

leucine biosynthetic process

Details: 
The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
GO Category: 
BP

GO:0009316

3-isopropylmalate dehydratase complex

Details: 
A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
GO Category: 
CC

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